(Q52840245)

English

The Aβ-clearance protein transthyretin, like neprilysin, is epigenetically regulated by the amyloid precursor protein intracellular domain.

scientific article published on 12 March 2014

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scholarly article

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

The Aβ-clearance protein transthyretin, like neprilysin, is epigenetically regulated by the amyloid precursor protein intracellular domain. (English)

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

author name string

Caroline Kerridge

1

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

Nikolai D Belyaev

2

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

Natalia N Nalivaeva

3

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

Anthony J Turner

4

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

language of work or name

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publication date

12 March 2014

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

Journal of Neurochemistry

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Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

130

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

3

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

419-431

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

An alternative metabolic pathway of amyloid precursor protein C-terminal fragments via cathepsin B in a human neuroglioma model

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Nuclear signalling by membrane protein intracellular domains: the AICD enigma

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The transcriptionally active amyloid precursor protein (APP) intracellular domain is preferentially produced from the 695 isoform of APP in a {beta}-secretase-dependent pathway

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

A short cytoplasmic domain of the amyloid precursor protein induces apoptosis in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-β1-42 oligomers are revealed in vivo by using a novel animal model.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

A weak base-generating system suitable for selective manipulation of lysosomal pH.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Altered levels of amyloid precursor protein intracellular domain-interacting proteins in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The amyloid precursor protein (APP)-cytoplasmic fragment generated by gamma-secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Identification of beta-amyloid-binding sites on transthyretin

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Gleevec increases levels of the amyloid precursor protein intracellular domain and of the amyloid-beta degrading enzyme neprilysin

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

gamma-Secretase substrate selectivity can be modulated directly via interaction with a nucleotide-binding site

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Twenty years of Alzheimer's disease-causing mutations

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

What is the dominant Abeta species in human brain tissue? A review

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The amyloid hypothesis for Alzheimer's disease: a critical reappraisal

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Alzheimer's disease: the amyloid cascade hypothesis

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The amyloid precursor protein represses expression of acetylcholinesterase in neuronal cell lines

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The impact of amyloid precursor protein signalling and histone deacetylase inhibition on neprilysin expression in human prostate cells

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Epigenetic control of aquaporin 1 expression by the amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Region-specific reduction of A beta-degrading endopeptidase, neprilysin, in mouse hippocampus upon aging.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

BACE is degraded via the lysosomal pathway

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The AbetaCs of Abeta-cleaving proteases

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Neuronal production of transthyretin in human and murine Alzheimer's disease: is it protective?

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Genetic and molecular aspects of Alzheimer's disease shed light on new mechanisms of transcriptional regulation.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD)

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The AICD interacting protein DAB1 is up-regulated in Alzheimer frontal cortex brain samples and causes deregulation of proteins involved in gene expression changes.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The amyloid precursor protein: a biochemical enigma in brain development, function and disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Are amyloid-degrading enzymes viable therapeutic targets in Alzheimer's disease?

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Effect of sodium valproate administration on brain neprilysin expression and memory in rats

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Gleevec inhibits β-amyloid production but not Notch cleavage

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The C-terminal fragment of the Alzheimer's disease amyloid protein precursor is degraded by a proteasome-dependent mechanism distinct from gamma-secretase

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

From synaptic spines to nuclear signaling: nuclear and synaptic actions of the amyloid precursor protein.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The physiology of the β-amyloid precursor protein intracellular domain AICD.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Amyloid precursor protein controls cholesterol turnover needed for neuronal activity

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Amyloid-independent mechanisms in Alzheimer's disease pathogenesis

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Purification of endopeptidase-24.11 ('enkephalinase') from pig brain by immunoadsorbent chromatography

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Proteolytic degradation of amyloid β-protein

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Transthyretin sequesters amyloid beta protein and prevents amyloid formation

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Preventing Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

c-Abl modulates AICD dependent cellular responses: transcriptional induction and apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Intracellular pH regulates amyloid precursor protein intracellular domain accumulation.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Alkalizing drugs induce accumulation of amyloid precursor protein by-products in luminal vesicles of multivesicular bodies

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Structure and expression of the alternatively-spliced forms of mRNA for the mouse homolog of Alzheimer's disease amyloid beta protein precursor.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Relationship between beta amyloid peptide generating molecules and neprilysin in Alzheimer disease and normal brain

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

The APP intracellular domain (AICD) inhibits Wnt signalling and promotes neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Ammonia inhibits phagosome–lysosome fusion in macrophages

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12680

21 January 2018

Identifiers

10.1111/JNC.12680

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

1 reference

Europe PubMed Central

8 May 2018

http://europepmc.org/abstract/MED/24528201

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