(Q52902753)

9 May 2018

review article

1 reference

title

Dual enigma of somatic hypermutation of immunoglobulin variable genes: targeting and mechanism. (English)

1 reference

9 May 2018

author name string

Winter DB

series ordinal

1

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9 May 2018

Gearhart PJ

series ordinal

2

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9 May 2018

publication date

1 April 1998

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9 May 2018

published in

Immunological Reviews

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9 May 2018

volume

162

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9 May 2018

page(s)

89-96

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9 May 2018

Early onset of somatic mutation in immunoglobulin VH genes during the primary immune response

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Differences between germ-line and rearranged immunoglobulin Vκ coding sequences suggest a localized mutation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Antibody diversity: somatic hypermutation of rearranged VH genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Mutations affecting fitness in Drosophila populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Targeting of non-Ig sequences in place of the V segment by somatic hypermutation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Boundaries of somatic mutation in rearranged immunoglobulin genes: 5' boundary is near the promoter, and 3' boundary is approximately 1 kb from V(D)J gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

A hyperconversion mechanism generates the chicken light chain preimmune repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Somatic diversification of immunoglobulin heavy chain VDJ genes: evidence for somatic gene conversion in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Somatic generation of diversity in a mammalian primary lymphoid organ: the sheep ileal Peyer's patches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Somatic variation precedes extensive diversification of germline sequences and combinatorial joining in the evolution of immunoglobulin heavy chain diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Analysis of somatic mutation in five B cell subsets of human tonsil

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Cells strongly expressing Ig(kappa) transgenes show clonal recruitment of hypermutation: a role for both MAR and the enhancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Isotype switching of an immunoglobulin heavy chain transgene occurs by DNA recombination between different chromosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Somatic hypermutation of immunoglobulin genes is linked to transcription initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

Insertion of 2 kb of bacteriophage DNA between an immunoglobulin promoter and leader exon stops somatic hypermutation in a kappa transgene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.1998.TB01432.X

10.1111/J.1600-065X.1998.TB01432.X

21 January 2018

Identifiers

DOI

1 reference

9 May 2018

PubMed ID

9602355

1 reference

9 May 2018