(Q53154841)

11 May 2018

title

Perinuclear localization of the HIV-1 regulatory protein Vpr is important for induction of G2-arrest. (English)

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11 May 2018

5

Thomas Stamminger

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11 May 2018

author name string

Stefan Sörgel

1

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11 May 2018

Kirsten Fraedrich

2

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11 May 2018

Jörg Votteler

3

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11 May 2018

Marco Thomas

4

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11 May 2018

Ulrich Schubert

6

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11 May 2018

language of work or name

English

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publication date

24 July 2012

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11 May 2018

published in

Virology

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11 May 2018

volume

432

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11 May 2018

issue

2

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11 May 2018

page(s)

444-451

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11 May 2018

HIV-1 Vpr: mechanisms of G2 arrest and apoptosis

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1 reference

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ATR and GADD45alpha mediate HIV-1 Vpr-induced apoptosis

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Induction of G2 arrest and binding to cyclophilin A are independent phenotypes of human immunodeficiency virus type 1 Vpr

7 January 2021

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Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest

7 January 2021

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HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase

7 January 2021

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HIV-1 Vpr induces the K48-linked polyubiquitination and proteasomal degradation of target cellular proteins to activate ATR and promote G2 arrest

7 January 2021

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Vpr cytopathicity independent of G2/M cell cycle arrest in human immunodeficiency virus type 1-infected CD4+ T cells

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The leader of human immunodeficiency virus type 1 genomic RNA harbors an internal ribosome entry segment that is active during the G2/M phase of the cell cycle

7 January 2021

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HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system

7 January 2021

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Cellular Distribution and Karyophilic Properties of Matrix, Integrase, and Vpr Proteins from the Human and Simian Immunodeficiency Viruses

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Caspases disrupt the nuclear-cytoplasmic barrier

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HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo

7 January 2021

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Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest

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Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

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Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages

7 January 2021

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SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles

7 January 2021

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Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.

7 January 2021

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

7 January 2021

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Activation of the ATR pathway by human immunodeficiency virus type 1 Vpr involves its direct binding to chromatin in vivo

7 January 2021

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The Vpr protein from HIV-1: distinct roles along the viral life cycle

7 January 2021

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A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex

7 January 2021

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Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism

7 January 2021

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Viral protein R regulates docking of the HIV-1 preintegration complex to the nuclear pore complex

7 January 2021

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Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

7 January 2021

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7 January 2021

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HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1

7 January 2021

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Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr.

7 January 2021

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Slipping through the door: HIV entry into the nucleus

7 January 2021

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Human immunodeficiency virus type 1 Vpr localization: nuclear transport of a viral protein modulated by a putative amphipathic helical structure and its relevance to biological activity

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.027

DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.027

Proline 35 of human immunodeficiency virus type 1 (HIV-1) Vpr regulates the integrity of the N-terminal helix and the incorporation of Vpr into virus particles and supports the replication of R5-tropic HIV-1 in human lymphoid tissue ex vivo

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.027

Essential role of active nuclear transport in apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.027

Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.027

Interaction of the human immunodeficiency virus type 1 Vpr protein with the nuclear pore complex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.027

7 January 2021

Human immunodeficiency virus type 1 (HIV-1) Vpr functions as an immediate-early protein during HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.027

7 January 2021

Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.027

7 January 2021

Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.027

7 January 2021

Augmentation of virus secretion by the human immunodeficiency virus type 1 Vpu protein is cell type independent and occurs in cultured human primary macrophages and lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIROL.2012.06.027

7 January 2021

10.1016/J.VIROL.2012.06.027

Identifiers

DOI

1 reference

11 May 2018

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11 May 2018