(Q53231709)

English

Staurosporine-induced activation of caspase-3 is potentiated by presenilin 1 familial Alzheimer's disease mutations in human neuroglioma cells.

scientific article published in December 1999

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

Staurosporine-induced activation of caspase-3 is potentiated by presenilin 1 familial Alzheimer's disease mutations in human neuroglioma cells. (English)

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

Alzheimer's disease

1 reference

based on heuristic

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author name string

Kovacs DM

1

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

Mancini R

2

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

Henderson J

3

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

Na SJ

4

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

Schmidt SD

5

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

Kim TW

6

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

Tanzi RE

7

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

language of work or name

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publication date

1 December 1999

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

Journal of Neurochemistry

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

73

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

6

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

2278-2285

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Alzheimer's disease associated presenilin-1 holoprotein and its 18-20 kDa C-terminal fragment are death substrates for proteases of the caspase family

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Processing of presenilin 1 in brains of patients with Alzheimer's disease and controls.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Increased apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin-2 mutation (N141I).

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Hyperaccumulation of FAD-linked presenilin 1 variants in vivo.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Evidence for a six-transmembrane domain structure of presenilin 1.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Presenilins are processed by caspase-type proteases.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

A cellular model that recapitulates major pathogenic steps of Huntington's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Different effects of Alzheimer-associated mutations of presenilin 1 on its processing

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Evidence for phosphorylation and oligomeric assembly of presenilin 1.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Stable association of presenilin derivatives and absence of presenilin interactions with APP.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Interfering with apoptosis: Ca(2+)-binding protein ALG-2 and Alzheimer's disease gene ALG-3

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Generation of anti-apoptotic presenilin-2 polypeptides by alternative transcription, proteolysis, and caspase-3 cleavage

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

1 reference

https://api.crossref.org/works/10.1046%2FJ.1471-4159.1999.0732278.X

21 January 2018

Identifiers

10.1046/J.1471-4159.1999.0732278.X

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 May 2018

http://europepmc.org/abstract/MED/10582585

ResearchGate publication ID

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