(Q53272755)

12 May 2018

title

CDKN2A homozygous deletion is associated with muscle invasion in FGFR3-mutated urothelial bladder carcinoma. (English)

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12 May 2018

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8

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Sandra Rebouissou

Sandra Rebouissou

1

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Mathilde Sibony

Mathilde Sibony

14

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Eric Letouzé

Eric Letouzé

3

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Yann Neuzillet

Yann Neuzillet

4

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François Radvanyi

François Radvanyi

19

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Simone Benhamou

Simone Benhamou

17

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author name string

Aurélie Hérault

2

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12 May 2018

Agnès Laplanche

5

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12 May 2018

Karina Ofualuka

6

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12 May 2018

Pascale Maillé

7

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Audrey Riou

9

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12 May 2018

May-Linda Lepage

10

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Dimitri Vordos

11

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Alexandre de la Taille

12

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Yves Denoux

13

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12 May 2018

Frédéric Guyon

15

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Thierry Lebret

16

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Yves Allory

18

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12 May 2018

publication date

8 May 2012

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12 May 2018

published in

Journal of Pathology

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12 May 2018

volume

227

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12 May 2018

page(s)

315-324

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12 May 2018

issue

3

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12 May 2018

Molecular subtypes of bladder cancer: Jekyll and Hyde or chalk and cheese?

cites work

1 reference

Molecular pathways in invasive bladder cancer: new insights into mechanisms, progression, and target identification

21 January 2018

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Urothelial tumorigenesis: a tale of divergent pathways

21 January 2018

1 reference

Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials.

21 January 2018

1 reference

Frequent FGFR3 mutations in papillary non-invasive bladder (pTa) tumors

21 January 2018

1 reference

Consistent genomic alterations in carcinoma in situ of the urinary bladder confirm the presence of two major pathways in bladder cancer development

21 January 2018

1 reference

The INK4a/ARF network in tumour suppression

21 January 2018

1 reference

Comprehensive analysis of CDKN2A status in microdissected urothelial cell carcinoma reveals potential haploinsufficiency, a high frequency of homozygous co-deletion and associations with clinical phenotype.

21 January 2018

1 reference

Deletions of the INK4A gene in superficial bladder tumors. Association with recurrence

21 January 2018

1 reference

p16 (CDKN2) is a major deletion target at 9p21 in bladder cancer.

21 January 2018

1 reference

Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.

21 January 2018

1 reference

Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders

21 January 2018

1 reference

Measurement of relative copy number of CDKN2A/ARF and CDKN2B in bladder cancer by real-time quantitative PCR and multiplex ligation-dependent probe amplification

21 January 2018

1 reference

The incidence of thanatophoric dysplasia mutations in FGFR3 gene is higher in low-grade or superficial bladder carcinomas.

21 January 2018

1 reference

Combined gene expression and genomic profiling define two intrinsic molecular subtypes of urothelial carcinoma and gene signatures for molecular grading and outcome.

21 January 2018

1 reference

Chromosome 9 deletions are more frequent than FGFR3 mutations in flat urothelial hyperplasias of the bladder.

21 January 2018

1 reference

Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification.

21 January 2018

1 reference

A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice

21 January 2018

1 reference

Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis.

21 January 2018

1 reference

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

21 January 2018

1 reference

Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

21 January 2018

1 reference

Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis.

21 January 2018

1 reference

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein

21 January 2018

1 reference

Deletion of the p16 and p15 Genes in Human Bladder Tumors

21 January 2018

1 reference

Metastasizing Melanoma Formation Caused by Expression of Activated N-RasQ61Kon an INK4a-Deficient Background

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/PATH.4017

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12 May 2018

PubMed ID

22422578

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12 May 2018