(Q53290255)

English

Inhibition of mammalian target of rapamycin signaling by everolimus induces senescence in adult T-cell leukemia/lymphoma and apoptosis in peripheral T-cell lymphomas.

scientific article published on 9 December 2010

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scholarly article

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

Inhibition of mammalian target of rapamycin signaling by everolimus induces senescence in adult T-cell leukemia/lymphoma and apoptosis in peripheral T-cell lymphomas. (English)

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

adult T-cell leukemia/lymphoma

1 reference

based on heuristic

inferred from title

Olivier Hermine

5

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

Nadine Darwiche

object named as

Nadine Darwiche

1

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object named as

Ali Bazarbachi

7

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2

object named as

Ansam Sinjab

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

6

object named as

Ghassan Dbaibo

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

Ghada Abou-Lteif

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object named as

Ghada Abou-Lteif

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

author name string

Mirella Bou Chedid

4

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

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publication date

9 December 2010

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

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12

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International Journal of Cancer

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

129

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

4

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

993-1004

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

Treatment of adult T-cell leukaemia/lymphoma: current strategy and future perspectives.

1 reference

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21 January 2018

Treatment with a combination of zidovudine and alpha-interferon in naive and pretreated adult T-cell leukemia/lymphoma patients.

1 reference

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Proapoptotic regimes for HTLV-I-transformed cells: targeting Tax and the NF-kappaB pathway

1 reference

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21 January 2018

Multiple viral strategies of HTLV-1 for dysregulation of cell growth control

1 reference

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Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation

1 reference

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21 January 2018

Insights into the molecular mechanism of p53 inhibition by HTLV type 1 Tax.

1 reference

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21 January 2018

Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.

1 reference

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21 January 2018

Mammalian target of rapamycin as a therapeutic target in leukemia

1 reference

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21 January 2018

mTOR and cancer therapy

1 reference

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21 January 2018

mTOR Mediated Anti-Cancer Drug Discovery

1 reference

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Mammalian target of rapamycin inhibition

1 reference

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21 January 2018

Mammalian target of rapamycin inhibitors and their potential role in therapy in leukaemia and other haematological malignancies

1 reference

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21 January 2018

N-(4-hydroxyphenyl)retinamide induces growth arrest and apoptosis in HTLV-I-transformed cells

1 reference

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21 January 2018

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

1 reference

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21 January 2018

Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25742

21 January 2018

Adult T-cell leukemia/lymphoma in the Middle East: first report of two cases from Lebanon

1 reference

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21 January 2018

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

1 reference

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21 January 2018

BAX frameshift mutations in cell lines derived from human haemopoietic malignancies are associated with resistance to apoptosis and microsatellite instability

1 reference

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21 January 2018

Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.

1 reference

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21 January 2018

Antiproliferative activity of RAD001 (everolimus) as a single agent and combined with other agents in mantle cell lymphoma

1 reference

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21 January 2018

Role for Akt/protein kinase B and activator protein-1 in cellular proliferation induced by the human T-cell leukemia virus type 1 tax oncoprotein

1 reference

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21 January 2018

Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I.

1 reference

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21 January 2018

mTOR inhibition and adult T-cell leukemia

1 reference

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21 January 2018

Therapeutic activity of mTOR inhibitors in mantle cell lymphoma: clues but no clear answers

1 reference

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21 January 2018

Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.

1 reference

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21 January 2018

PUMA couples the nuclear and cytoplasmic proapoptotic function of p53

1 reference

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21 January 2018

DNA-PK phosphorylates histone H2AX during apoptotic DNA fragmentation in mammalian cells

1 reference

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21 January 2018

AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001.

1 reference

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21 January 2018

Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells

1 reference

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21 January 2018

Inhibition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in hematologic malignancies.

1 reference

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21 January 2018

Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25742

21 January 2018

Targeting the phosphoinositide 3-kinase pathway in cancer

1 reference

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21 January 2018

PI3K/AKT inhibition induces caspase-dependent apoptosis in HTLV-1-transformed cells

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25742

21 January 2018

Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25742

21 January 2018

Targeting the mTOR signaling network for cancer therapy

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25742

21 January 2018

Perspectives on inhibiting mTOR as a future treatment strategy for hematological malignancies

1 reference

https://api.crossref.org/works/10.1002%2FIJC.25742

21 January 2018

PTEN and the PI3-kinase pathway in cancer

1 reference

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21 January 2018

Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma

1 reference

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21 January 2018

Temsirolimus has activity in non-mantle cell non-Hodgkin's lymphoma subtypes: The University of Chicago phase II consortium

1 reference

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A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies

1 reference

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21 January 2018

Mammalian target of rapamycin inhibition as therapy for hematologic malignancies

1 reference

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21 January 2018

Combinations of mTORC1 inhibitor RAD001 with gemcitabine and paclitaxel for treating non-Hodgkin lymphoma

1 reference

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Targeting tumorigenesis: development and use of mTOR inhibitors in cancer therapy

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Meta-Analysis on the Use of Zidovudine and Interferon-Alfa in Adult T-Cell Leukemia/Lymphoma Showing Improved Survival in the Leukemic Subtypes

1 reference

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21 January 2018

Identifiers

10.1002/IJC.25742

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

1 reference

Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/21064094

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