(Q53351910)

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Significant structural differences between transient amyloid-β oligomers and less-toxic fibrils in regions known to harbor familial Alzheimer's mutations.

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15 March 2020

Significant structural differences between transient amyloid-β oligomers and less-toxic fibrils in regions known to harbor familial Alzheimer's mutations (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24756858%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

Alzheimer's disease

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8

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15 March 2020

1

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15 March 2020

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Venus Singh Mithu

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15 March 2020

Bappaditya Chandra

3

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15 March 2020

Arghya Mandal

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15 March 2020

Muralidharan Chandrakesan

5

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15 March 2020

Debanjan Bhowmik

6

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15 March 2020

Perunthiruthy K Madhu

7

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23 April 2014

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15 March 2020

Angewandte Chemie International Edition

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15 March 2020

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27

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15 March 2020

6888-6892

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15 March 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

A beta oligomers - a decade of discovery

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Structure-neurotoxicity relationships of amyloid beta-protein oligomers

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

A folding transition underlies the emergence of membrane affinity in amyloid-β.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Structural conversion of neurotoxic amyloid-beta(1-42) oligomers to fibrils

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

The Alzheimer's amyloid-β(1-42) peptide forms off-pathway oligomers and fibrils that are distinguished structurally by intermolecular organization

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Toxic fibrillar oligomers of amyloid-β have cross-β structure

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Structural characterization of a soluble amyloid beta-peptide oligomer.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Solid-state NMR spectroscopic investigation of Aβ protofibrils: implication of a β-sheet remodeling upon maturation into terminal amyloid fibrils.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Structures of oligomers of a peptide from β-amyloid

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

3D structure of Alzheimer's amyloid-beta(1-42) fibrils

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Molecular structural basis for polymorphism in Alzheimer's -amyloid fibrils

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

A new structural model of Aβ40 fibrils.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Zn(++) binding disrupts the Asp(23)-Lys(28) salt bridge without altering the hairpin-shaped cross-β Structure of Aβ(42) amyloid aggregates.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Thermodynamically stable amyloid-β monomers have much lower membrane affinity than the small oligomers.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Single molecule characterization of the interactions between amyloid-β peptides and the membranes of hippocampal cells

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Nature of the amyloid-beta monomer and the monomer-oligomer equilibrium.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

pH changes the aggregation propensity of amyloid-β without altering the monomer conformation.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Nanofluidic biosensing for beta-amyloid detection using surface enhanced Raman spectroscopy

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Effect of the Tottori familial disease mutation (D7N) on the monomers and dimers of Aβ40 and Aβ42.

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Locus-specific mutation databases for neurodegenerative brain diseases

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Familial Alzheimer A2 V mutation reduces the intrinsic disorder and completely changes the free energy landscape of the Aβ1-28 monomer

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Capturing intermediate structures of Alzheimer's beta-amyloid, Abeta(1-40), by solid-state NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Measuring diffusion in cell membranes by fluorescence correlation spectroscopy

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201402636

21 January 2018

Identifiers

10.1002/ANIE.201402636

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24756858%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24756858%20AND%20SRC:MED&resulttype=core&format=json

15 March 2020

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