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Inhibition of Rho GTPases using protein geranylgeranyltransferase I inhibitors.
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scholarly article
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stated in
Europe PubMed Central
PubMed publication ID
11036620
retrieved
14 May 2018
reference URL
http://europepmc.org/abstract/MED/11036620
title
Inhibition of Rho GTPases using protein geranylgeranyltransferase I inhibitors.
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11036620
retrieved
14 May 2018
reference URL
http://europepmc.org/abstract/MED/11036620
author name string
Sebti SM
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11036620
retrieved
14 May 2018
reference URL
http://europepmc.org/abstract/MED/11036620
Hamilton AD
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11036620
retrieved
14 May 2018
reference URL
http://europepmc.org/abstract/MED/11036620
language of work or name
English
0 references
publication date
1 January 2000
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11036620
retrieved
14 May 2018
reference URL
http://europepmc.org/abstract/MED/11036620
published in
Methods in Enzymology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11036620
retrieved
14 May 2018
reference URL
http://europepmc.org/abstract/MED/11036620
volume
325
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11036620
retrieved
14 May 2018
reference URL
http://europepmc.org/abstract/MED/11036620
page(s)
381-388
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11036620
retrieved
14 May 2018
reference URL
http://europepmc.org/abstract/MED/11036620
cites work
Cell signaling: an overview
1 reference
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7 January 2021
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Signal transduction pathways that regulate cell survival and cell death
1 reference
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https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
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7 January 2021
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Cell growth control by G protein-coupled receptors: from signal transduction to signal integration
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
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7 January 2021
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Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis.
1 reference
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https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
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7 January 2021
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Regulation of cell proliferation by G proteins
1 reference
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7 January 2021
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Anti-apoptotic versus pro-apoptotic signal transduction: checkpoints and stop signs along the road to death.
1 reference
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7 January 2021
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Increasing complexity of Ras signaling.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
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7 January 2021
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Rho family proteins and Ras transformation: the RHOad less traveled gets congested.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
retrieved
7 January 2021
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Signal transduction. How receptors turn Ras on.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
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7 January 2021
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Comparative biochemical properties of normal and activated human ras p21 protein
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
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7 January 2021
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The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
retrieved
7 January 2021
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inferred from DOI database lookup
ras genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
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7 January 2021
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Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation.
1 reference
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Crossref
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7 January 2021
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Inhibition of Ras prenylation: a novel approach to cancer chemotherapy
1 reference
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7 January 2021
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The potential of farnesyltransferase inhibitors as cancer chemotherapeutics
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
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7 January 2021
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inferred from DOI database lookup
Protein prenylation: molecular mechanisms and functional consequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A non-peptide mimetic of Ras-CAAX: selective inhibition of farnesyltransferase and Ras processing
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
retrieved
7 January 2021
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inferred from DOI database lookup
Disruption of Oncogenic K-Ras4B Processing and Signaling by a Potent Geranylgeranyltransferase I Inhibitor
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
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7 January 2021
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Ras CAAX Peptidomimetic FTI-277 Selectively Blocks Oncogenic Ras Signaling by Inducing Cytoplasmic Accumulation of Inactive Ras-Raf Complexes
1 reference
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Crossref
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7 January 2021
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Design and synthesis of non-peptide Ras CAAX mimetics as potent farnesyltransferase inhibitors
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylation
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
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7 January 2021
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inferred from DOI database lookup
Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The geranylgeranyltransferase I inhibitor GGTI-298 induces hypophosphorylation of retinoblastoma and partner switching of cyclin-dependent kinase inhibitors. A potential mechanism for GGTI-298 antitumor activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2800%2925459-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0076-6879(00)25459-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11036620
retrieved
14 May 2018
reference URL
http://europepmc.org/abstract/MED/11036620
PubMed publication ID
11036620
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11036620
retrieved
14 May 2018
reference URL
http://europepmc.org/abstract/MED/11036620
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