(Q53566237)

English

Frequency of Hprt mutant lymphocytes and micronucleated erythrocytes in p53-haplodeficient mice treated perinatally with AZT and AZT in combination with 3TC.

scientific article published in April 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Frequency of Hprt mutant lymphocytes and micronucleated erythrocytes in p53-haplodeficient mice treated perinatally with AZT and AZT in combination with 3TC. (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

author name string

Vasily N Dobrovolsky

1

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Joseph G Shaddock

2

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Roberta A Mittelstaedt

3

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Michelle E Bishop

4

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Sherry M Lewis

5

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Fei W Lee

6

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Anane Aidoo

7

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Julian E A Leakey

8

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

June K Dunnick

9

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Robert H Heflich

10

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

publication date

1 April 2007

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Environmental and Molecular Mutagenesis

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

48

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

3-4

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

270-282

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

Software for the analysis of mutations at the human hprt gene.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

21 January 2018

Specific-locus mutations induced in eukaryotes (especially mammalian cells) by radiation and chemicals: a perspective

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

21 January 2018

Micronucleated CD71-positive reticulocytes: a blood-based endpoint of cytogenetic damage in humans

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

21 January 2018

Micronucleated erythrocyte frequency in control and azidothymidine-treated Tk+/+, Tk+/- and Tk-/- mice

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

21 January 2018

Analysis of mutations in the Tk gene of Tk(+/-) mice treated as neonates with 3'-azido-3'-deoxythymidine (AZT).

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

21 January 2018

The role of transgenic mouse models in carcinogen identification

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https://api.crossref.org/works/10.1002%2FEM.20280

21 January 2018

Frequency and types of spontaneous Hprt lymphocyte mutations in Pms2-deficient mice

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

21 January 2018

Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog

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https://api.crossref.org/works/10.1002%2FEM.20280

21 January 2018

Statistical test for the comparison of samples from mutational spectra

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7 January 2021

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Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats

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7 January 2021

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Zidovudine: a review of its use in the management of vertically-acquired pediatric HIV infection

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https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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Oxidative DNA damage in fetal tissues after transplacental exposure to 3'-azido-3'-deoxythymidine (AZT)

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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Molecular insights into NRTI inhibition and mitochondrial toxicity revealed from a structural model of the human mitochondrial DNA polymerase.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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Cellular metabolism of (−) enantiomeric 2′-deoxy-3′-thiacytidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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7,12-dimethylbenz[a]anthracene-induced mutation in the Tk gene of Tk(+/-) mice: automated scoring of lymphocyte clones using a fluorescent viability indicator.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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The nature of the heterozygous Trp53 knockout model for identification of mutagenic carcinogens

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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The intracellular phosphorylation of (-)-2'-deoxy-3'-thiacytidine (3TC) and the incorporation of 3TC 5'-monophosphate into DNA by HIV-1 reverse transcriptase and human DNA polymerase gamma

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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Use of transgenic animals for carcinogenicity testing: considerations and implications for risk assessment

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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The induction of micronuclei as a measure of genotoxicity. A report of the U.S. Environmental Protection Agency Gene-Tox Program.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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Induction of hprt gene mutations in splenic T-lymphocytes from the rat exposed in vivo to DNA methylating agents is correlated with formation of O6-methylguanine in bone marrow and not in the spleen

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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Clinical pharmacokinetics of lamivudine

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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Lamivudine (3TC) phosphorylation and drug interactions in vitro

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

inferred from DOI database lookup

Generation of mutant mice with large chromosomal deletion by use of irradiated ES cells--analysis of large deletion around hprt locus of ES cell

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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The in vivo erythrocyte micronucleus test: measurement at steady state increases assay efficiency and permits integration with toxicity studies

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1.

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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Mutagenicity and loss of heterozygosity at the APRT locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells

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https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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Rapid induction of uterine tumors with p53 point mutations in heterozygous p53-deficient CBA mice given a single intraperitoneal administration of N-ethyl-N-nitrosourea

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https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro

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https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs

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https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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Effects of perinatal zidovudine on hematopoiesis: a comparison of effects on progenitors from human fetuses versus mothers

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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P53+/- hemizygous knockout mouse: overview of available data

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7 January 2021

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Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models

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https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in B6C3F(1)/Tk+/- mice treated neonatally with zidovudine and lamivudine

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

based on heuristic

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Relationships between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea

1 reference

https://api.crossref.org/works/10.1002%2FEM.20280

7 January 2021

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3'-azido-3'-deoxythymidine induces deletions in L5178Y mouse lymphoma cells

1 reference

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7 January 2021

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Genetic damage detected in CD-1 mouse pups exposed perinatally to 3'-azido-3'-deoxythymidine or dideoxyinosine via maternal dosing, nursing, and direct gavage: II. Effects of the individual agents compared to combination treatment

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7 January 2021

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Identifiers

10.1002/EM.20280

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 May 2018

http://europepmc.org/abstract/MED/17358030

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