(Q53668736)

English

TRAIL-induced apoptosis in human vascular endothelium is regulated by phosphatidylinositol 3-kinase/Akt through the short form of cellular FLIP and Bcl-2.

scientific article published on 28 June 2005

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15985761%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

TRAIL-induced apoptosis in human vascular endothelium is regulated by phosphatidylinositol 3-kinase/Akt through the short form of cellular FLIP and Bcl-2 (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15985761%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

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13 January 2020

author name string

Salima J Alladina

1

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13 January 2020

Sandra T Davidge

3

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13 January 2020

Chunhai Hao

4

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13 January 2020

Alexander S Easton

5

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13 January 2020

publication date

28 June 2005

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13 January 2020

Journal of Vascular Research

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13 January 2020

42

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13 January 2020

4

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13 January 2020

337-347

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13 January 2020

Endothelial cell apoptosis induced by oxidized LDL is associated with the down-regulation of the cellular caspase inhibitor FLIP.

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Oxidative stress as a mediator of apoptosis

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Role of Akt signaling in vascular homeostasis and angiogenesis

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

The phosphoinositide 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Oxidized LDL inhibits vascular endothelial growth factor-induced endothelial cell migration by an inhibitory effect on the Akt/endothelial nitric oxide synthase pathway

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Angiotensin II type 2 receptor inhibits vascular endothelial growth factor-induced migration and in vitro tube formation of human endothelial cells.

1 reference

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21 January 2018

Thromboxane A2 receptor signaling inhibits vascular endothelial growth factor-induced endothelial cell differentiation and migration

1 reference

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21 January 2018

Canstatin inhibits Akt activation and induces Fas-dependent apoptosis in endothelial cells

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

An induced proximity model for caspase-8 activation.

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Mitochondria as the central control point of apoptosis

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Inhibition of death receptor signals by cellular FLIP

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Calcium/calmodulin-dependent protein kinase II regulation of c-FLIP expression and phosphorylation in modulation of Fas-mediated signaling in malignant glioma cells

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA.

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

LY294002 inhibits monocyte chemoattractant protein-1 expression through a phosphatidylinositol 3-kinase-independent mechanism

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

LY294002, but not wortmannin, increases intracellular calcium and inhibits calcium transients in bovine and human airway smooth muscle cells

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) inhibits nitric oxide production in cultured murine astrocytes

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

The phosphatidylinositol 3-kinase inhibitor LY294002 binds the estrogen receptor and inhibits 17beta-estradiol-induced transcriptional activity of an estrogen sensitive reporter gene

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Synthesis and function of 3-phosphorylated inositol lipids

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Mitochondrial control of cell death

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

The protein kinase B/Akt signalling pathway in human malignancy

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

NF-kappaB at the crossroads of life and death

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Structural elements of kallistatin required for inhibition of angiogenesis

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Inhibition of Akt phosphorylation by thrombin, histamine and lysophosphatidylcholine in endothelial cells. Differential role of protein kinase C.

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Nitric oxide acts on the mitochondria and protects human endothelial cells from apoptosis

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sequentially upregulates nitric oxide and prostanoid production in primary human endothelial cells

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Matrix attachment regulates Fas-induced apoptosis in endothelial cells: a role for c-flip and implications for anoikis

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1159%2F000086599

21 January 2018

TRAIL Promotes the Survival and Proliferation of Primary Human Vascular Endothelial Cells by Activating the Akt and ERK Pathways

1 reference

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21 January 2018

Identifiers

10.1159/000086599

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15985761%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15985761%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

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