(Q54062885)

24 May 2018

title

Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer. (English)

1 reference

24 May 2018

author

Hiroyuki Seimiya

4

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24 May 2018

Christopher J Lord

5

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24 May 2018

Alan Ashworth

6

object named as

A Ashworth

1 reference

24 May 2018

N McCabe

1

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24 May 2018

M A Cerone

2

1 reference

24 May 2018

T Ohishi

3

1 reference

24 May 2018

language of work or name

English

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publication date

2 February 2009

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24 May 2018

published in

Oncogene

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24 May 2018

volume

28

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24 May 2018

issue

11

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24 May 2018

page(s)

1465-1470

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24 May 2018

https://scigraph.springernature.com/pub.10.1038/onc.2008.483

exact match

0 references

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

NuMA is a major acceptor of poly(ADP-ribosyl)ation by tankyrase 1 in mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Tankyrase is a golgi-associated mitogen-activated protein kinase substrate that interacts with IRAP in GLUT4 vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

A DNA damage checkpoint response in telomere-initiated senescence

21 January 2018

1 reference

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Shelterin: the protein complex that shapes and safeguards human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Resolution of sister telomere association is required for progression through mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

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Utilizing RNA interference to enhance cancer drug discovery

21 January 2018

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The concept of synthetic lethality in the context of anticancer therapy

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1 reference

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Substrate-assisted catalysis by PARP10 limits its activity to mono-ADP-ribosylation.

21 January 2018

1 reference

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Centrosome aberrations: cause or consequence of cancer progression?

21 January 2018

1 reference

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The telomeric PARP, tankyrases, as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Second-generation shRNA libraries covering the mouse and human genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Hallmarks of 'BRCAness' in sporadic cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

21 January 2018

1 reference

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Exploiting the DNA Repair Defect in BRCA Mutant Cells in the Design of New Therapeutic Strategies for Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.483

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.483

1 reference

24 May 2018

1 reference

24 May 2018