(Q54201365)

26 May 2018

title

Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb/E2f-signalling. (English)

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26 May 2018

author

Dieter Adam

6

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26 May 2018

author name string

Susanne Hille

1

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26 May 2018

Franziska Dierck

2

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26 May 2018

Constantin Kühl

3

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26 May 2018

Justyna Sosna

4

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26 May 2018

Sabine Adam-Klages

5

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26 May 2018

Renate Lüllmann-Rauch

7

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26 May 2018

Norbert Frey

8

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26 May 2018

Christian Kuhn

9

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26 May 2018

publication date

7 April 2016

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26 May 2018

published in

Cardiovascular Research

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26 May 2018

volume

110

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26 May 2018

issue

3

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26 May 2018

page(s)

381-394

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26 May 2018

Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region"

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DYRK1A is a novel negative regulator of cardiomyocyte hypertrophy

21 January 2018

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Enhanced expression of DYRK1A in cardiomyocytes inhibits acute NFAT activation but does not prevent hypertrophy in vivo

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Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice

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Targeted inhibition of calcineurin attenuates cardiac hypertrophy in vivo

21 January 2018

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Dysbindin is a potent inducer of RhoA-SRF-mediated cardiomyocyte hypertrophy

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Targeted expression of cyclin D2 results in cardiomyocyte DNA synthesis and infarct regression in transgenic mice

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High-level expression of the Mnb/Dyrk1A gene in brain and heart during rat early development.

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Expression and activities of cyclins and cyclin-dependent kinases in developing rat ventricular myocytes

21 January 2018

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Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle

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DYRK1A-mediated Cyclin D1 Degradation in Neural Stem Cells Contributes to the Neurogenic Cortical Defects in Down Syndrome

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The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation

21 January 2018

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DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3

21 January 2018

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Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins

21 January 2018

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Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

21 January 2018

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Glycogen synthase kinase-3beta and p38 phosphorylate cyclin D2 on Thr280 to trigger its ubiquitin/proteasome-dependent degradation in hematopoietic cells

21 January 2018

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cAMP-induced degradation of cyclin D3 through association with GSK-3beta

21 January 2018

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Involvement of cyclin D activity in left ventricle hypertrophy in vivo and in vitro

21 January 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

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Changes in E2F complexes containing retinoblastoma protein family members and increased cyclin-dependent kinase inhibitor activities during terminal differentiation of cardiomyocytes

21 January 2018

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RB and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Adenovirus E1A directly targets the E2F/DP-1 complex

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

E2F target genes: unraveling the biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling

21 January 2018

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Tumor suppressor DYRK1A effects on proliferation and chemoresistance of AML cells by downregulating c-Myc

21 January 2018

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Cardiac myocyte cell cycle control in development, disease, and regeneration

21 January 2018

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Inhibition of E2F abrogates the development of cardiac myocyte hypertrophy

21 January 2018

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The Ki-67 protein: from the known and the unknown

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Phosphorylation of histone H3 at serine 10 is correlated with chromosome condensation during mitosis and meiosis in Tetrahymena

21 January 2018

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https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Regulation of the cardiomyocyte population in the developing heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure

21 January 2018

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DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly

21 January 2018

1 reference

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Binucleation of cardiomyocytes: the transition from a proliferative to a terminally differentiated state

21 January 2018

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Long-term cardiovascular effects of neonatal dexamethasone treatment: hemodynamic follow-up by left ventricular pressure-volume loops in rats

21 January 2018

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Histopathological changes of the heart after neonatal dexamethasone treatment: studies in 4-, 8-, and 50-week-old rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Development of mice expressing a single D-type cyclin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Mouse development and cell proliferation in the absence of D-cyclins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Cardiomyocyte cell cycle activation improves cardiac function after myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

G1 cyclins are involved in the mechanism of cardiac myocyte hypertrophy induced by angiotensin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Phosphorylation of pRb by cyclin D kinase is necessary for development of cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

A cyclin D2-Rb pathway regulates cardiac myocyte size and RNA polymerase III after biomechanical stress in adult myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

The role of modulatory calcineurin-interacting proteins in calcineurin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Ethnicity, sex, and the incidence of congenital heart defects: a report from the National Down Syndrome Project

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

Suppression of physiological cardiomyocyte proliferation in the rat pup after neonatal glucocorticosteroid treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVW074

21 January 2018

Identifiers

DOI

10.1093/CVR/CVW074

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26 May 2018

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26 May 2018