(Q54435795)

English

Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors.

scientific article published on 21 August 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors. (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

author name string

Ira B Dicker

1

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Himadri K Samanta

2

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Zhufang Li

3

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Yang Hong

4

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Yuan Tian

5

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Jacques Banville

6

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Roger R Remillard

7

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Michael A Walker

8

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

David R Langley

9

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Mark Krystal

10

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

language of work or name

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publication date

21 August 2007

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

282

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

43

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

31186-31196

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

Molecular mechanism of retroviral DNA integration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Retroviral DNA integration directed by HIV integration protein in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

HIV-1 integrase crosslinked oligomers are active in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Relationship between the oligomeric status of HIV-1 integrase on DNA and enzymatic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Recombinant human immunodeficiency virus type 1 integrase exhibits a capacity for full-site integration in vitro that is comparable to that of purified preintegration complexes from virus-infected cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Processing of viral DNA ends channels the HIV-1 integration reaction to concerted integration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Efficient concerted integration by recombinant human immunodeficiency virus type 1 integrase without cellular or viral cofactors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Retroviral DNA integration: reaction pathway and critical intermediates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Integrase inhibitors to treat HIV/AIDS.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Identification of amino acids in HIV-1 and avian sarcoma virus integrase subsites required for specific recognition of the long terminal repeat Ends

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Two-metal active site binding of a Tn5 transposase synaptic complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Kinetic study of the HIV-1 DNA 3'-end processing.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Integration of human immunodeficiency virus DNA: adduct interference analysis of required DNA sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type-1 integrase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Stereospecificity of reactions catalyzed by HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Disruption of the terminal base pairs of retroviral DNA during integration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

The core domain of HIV-1 integrase recognizes key features of its DNA substrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

HIV-1 integrase can process a 3'-end crosslinked substrate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Pre-organized structure of viral DNA at the binding-processing site of HIV-1 integrase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Probing of HIV-1 integrase/DNA interactions using novel analogs of viral DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Integration requires a specific interaction of the donor DNA terminal 5'-cytosine with glutamine 148 of the HIV-1 integrase flexible loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Preliminary mapping of a putative inhibitor-binding pocket for human immunodeficiency virus type 1 integrase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Genetic analyses of DNA-binding mutants in the catalytic core domain of human immunodeficiency virus type 1 integrase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Molecular dynamics studies on the HIV-1 integrase catalytic domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Brownian and essential dynamics studies of the HIV-1 integrase catalytic domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Comparative molecular dynamics simulations of HIV-1 integrase and the T66I/M154I mutant: binding modes and drug resistance to a diketo acid inhibitor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Human immunodeficiency virus type-1 integrase containing a glycine to serine mutation at position 140 is attenuated for catalysis and resistant to integrase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Dihydroxythiophenes are novel potent inhibitors of human immunodeficiency virus integrase with a diketo acid-like pharmacophore

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Molecular dynamics studies of the wild-type and double mutant HIV-1 integrase complexed with the 5CITEP inhibitor: mechanism for inhibition and drug resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Investigations on human immunodeficiency virus type 1 integrase/DNA binding interactions via molecular dynamics and electrostatics calculations.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Major and minor groove contacts in retroviral integrase-LTR interactions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M704935200

21 January 2018

Identifiers

10.1074/JBC.M704935200

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 May 2018

http://europepmc.org/abstract/MED/17715137

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