(Q54573803)

1 June 2018

title

Thymosin beta4 triggers an epithelial-mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase. (English)

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1 June 2018

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H-C Huang

1

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1 June 2018

C-H Hu

2

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1 June 2018

M-C Tang

3

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1 June 2018

W-S Wang

4

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1 June 2018

P-M Chen

5

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1 June 2018

Y Su

6

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1 June 2018

language of work or name

English

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publication date

30 October 2006

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1 June 2018

published in

Oncogene

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1 June 2018

volume

26

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1 June 2018

issue

19

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1 June 2018

page(s)

2781-2790

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1 June 2018

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210078

exact match

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cites work

Integration of cell attachment, cytoskeletal localization, and signaling by integrin-linked kinase (ILK), CH-ILKBP, and the tumor suppressor PTEN.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

The integrin-actin connection, an eternal love affair

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

The renaissance of GSK3

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

RAS and RHO GTPases in G1-phase cell-cycle regulation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via alpha-PIX.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Integrin-linked kinase: a cancer therapeutic target unique among its ILK.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

The extracellular signal-regulated kinase pathway regulates the phosphorylation of 4E-BP1 at multiple sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of beta-catenin from cell-cell contacts

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Epithelial-mesenchymal transitions: twist in development and metastasis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Biochemical processing of E-cadherin under cellular stress

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Regulation of beta-catenin signaling in the Wnt pathway

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Role of morphogenetic factors in metastasis of mammary carcinoma cells.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Loss of heterozygosity of APC and CDH1 genes in laryngeal squamous cell carcinoma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

A new role for E12/E47 in the repression of E-cadherin expression and epithelial-mesenchymal transitions.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

A causal role for E-cadherin in the transition from adenoma to carcinoma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Casein kinase 1: a Wnt'er of disconnect

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

The cadherin-catenin system: implications for growth and differentiation of endocrine tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Functional correlates of mutations in beta-catenin exon 3 phosphorylation sites

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Mutations of the E-cadherin gene in human gynecologic cancers.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Autocrine transforming growth factor alpha regulates cell adhesion by multiple signaling via specific phosphorylation sites of p70S6 kinase in colon cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Morphogenetic roles of classic cadherins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Epithelial-mesenchymal transitions in tumour progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Cell-cell dissociation upon epithelial cell scattering requires a step mediated by the proteasome

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Tumor metastasis: a new twist on epithelial-mesenchymal transitions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Overexpression of the thymosin beta-4 gene is associated with malignant progression of SW480 colon cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Overexpression of the thymosin beta-4 gene is associated with increased invasion of SW480 colon carcinoma cells and the distant metastasis of human colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Wnt-induced dephosphorylation of axin releases beta-catenin from the axin complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Integrin-linked protein kinase regulates fibronectin matrix assembly, E-cadherin expression, and tumorigenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Molecular cloning and structural characterization of the functional human thymosin beta4 gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth, and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xe

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Critical appraisal of the use of matrix metalloproteinase inhibitors in cancer treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210078

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210078

1 reference

1 June 2018

PubMed ID

17072345

1 reference

1 June 2018