(Q54589108)

1 June 2018

title

Alkaline stress-induced autophagy is mediated by mTORC1 inactivation. (English)

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1 June 2018

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Jinkyu Suk

1

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1 June 2018

Sang Su Kwak

2

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Jae Ho Lee

3

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Ji Hye Choi

4

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Sang-Hee Lee

5

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Dong Hwan Lee

6

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1 June 2018

Boohyeong Byun

7

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Geon-Hyoung Lee

8

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1 June 2018

Cheol O Joe

9

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publication date

1 September 2011

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1 June 2018

Journal of Cellular Biochemistry

published in

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volume

112

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issue

9

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page(s)

2566-2573

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Screen for chemical modulators of autophagy reveals novel therapeutic inhibitors of mTORC1 signaling

cites work

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mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex

21 January 2018

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Ammonia derived from glutaminolysis is a diffusible regulator of autophagy

21 January 2018

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Maturation of autophagic vacuoles in Mammalian cells

21 January 2018

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Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

21 January 2018

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Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

21 January 2018

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Photoconversion of Lysotracker Red to a green fluorescent molecule.

21 January 2018

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Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions

21 January 2018

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Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34.

21 January 2018

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Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition

21 January 2018

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Restraining PI3K: mTOR signalling goes back to the membrane.

21 January 2018

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Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

21 January 2018

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Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2.

21 January 2018

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

21 January 2018

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Constitutively active Rheb induces oncogenic transformation

21 January 2018

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ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

21 January 2018

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mTOR regulation of autophagy

21 January 2018

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mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

21 January 2018

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The molecular machinery of autophagy: unanswered questions

21 January 2018

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mTOR signaling at a glance

21 January 2018

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Autophagy in the Pathogenesis of Disease

21 January 2018

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Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency

21 January 2018

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Regulation of intracellular pH in eukaryotic cells

21 January 2018

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Prevention of mitochondrial injury by manganese superoxide dismutase reveals a primary mechanism for alkaline-induced cell death

21 January 2018

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Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis

21 January 2018

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Ammonium in nervous tissue: transport across cell membranes, fluxes from neurons to glial cells, and role in signalling

21 January 2018

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Autophagy fights disease through cellular self-digestion

21 January 2018

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mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

21 January 2018

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Regulation of macroautophagy by mTOR and Beclin 1 complexes

21 January 2018

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Microtubule assembly and disassembly at alkaline pH

21 January 2018

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Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH.

21 January 2018

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Potential therapeutic applications of autophagy

21 January 2018

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

21 January 2018

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Growing roles for the mTOR pathway

21 January 2018

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Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies

21 January 2018

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Akt/protein kinase B promotes organ growth in transgenic mice

21 January 2018

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Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR.

21 January 2018

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Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

21 January 2018

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TOR signaling in growth and metabolism

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCB.23181

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1 June 2018

release_o76vwimtwrfedmnltxtfn3qcr4

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/o76vwimtwrfedmnltxtfn3qcr4

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

21590709

1 reference

1 June 2018