(Q55053379)

English

Alzheimer's disease: Selectively tuning gamma-secretase.

scientific article

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scholarly article

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

Alzheimer's disease: Selectively tuning gamma-secretase. (English)

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

Alzheimer's disease

1 reference

based on heuristic

inferred from title

Peter Henry St George-Hyslop

1

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

Gerold Schmitt-Ulms

2

object named as

Gerold Schmitt-Ulms

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

language of work or name

0 references

publication date

1 September 2010

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

467

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

7311

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

36-37

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

https://scigraph.springernature.com/pub.10.1038/467036a

0 references

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TMP21 transmembrane domain regulates gamma-secretase cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orphan G protein-coupled receptor 3 modulates amyloid-beta peptide generation in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate-targeting gamma-secretase modulators

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gleevec inhibits β-amyloid production but not Notch cleavage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicastrin binds to membrane-tethered Notch

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20811445

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/467036A

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/MED/20811445

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