(Q55070749)

English

Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes.

scientific article published on 10 October 2014

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Autoreactive T cells induce necrosis and not BCL-2-regulated or death receptor-mediated apoptosis or RIPK3-dependent necroptosis of transplanted islets in a mouse model of type 1 diabetes (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

type-1 diabetes

0 references

1 reference

based on heuristic

inferred from title

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Andreas Strasser

7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Nicholas A Scott

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

W. Wei-Lynn Wong

5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

8

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

author name string

Yuxing Zhao

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Stacey Fynch

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Lorraine Elkerbout

4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Thomas W H Kay

9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Helen E Thomas

10

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

publication date

10 October 2014

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

58

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

140-148

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25301392%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

https://scigraph.springernature.com/pub.10.1007/s00125-014-3407-5

0 references

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Pathogenic mechanisms in type 1 diabetes: the islet is both target and driver of disease

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Programmed cell death in animal development and disease

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

XIAP discriminates between type I and type II FAS-induced apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

The proapoptotic BH3-only proteins Bim and Puma are downstream of endoplasmic reticulum and mitochondrial oxidative stress in pancreatic islets in response to glucotoxicity

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Molecular mechanisms of necroptosis: an ordered cellular explosion

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Beta cell apoptosis in T cell-mediated autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Transmembrane TNF and IFNgamma induce caspase-independent death of primary mouse pancreatic beta cells

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Proapoptotic BH3-only protein Bid is essential for death receptor-induced apoptosis of pancreatic beta-cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Interleukin-1 stimulates beta-cell necrosis and release of the immunological adjuvant HMGB1

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor alpha.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Transgenic expression of dominant-negative Fas-associated death domain protein in beta cells protects against Fas ligand-induced apoptosis and reduces spontaneous diabetes in nonobese diabetic mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

The pro-apoptotic BH3-only protein Bid is dispensable for development of insulitis and diabetes in the non-obese diabetic mouse

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Mechanisms of beta cell death in diabetes: a minor role for CD95.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Bioluminescence imaging in mouse models quantifies beta cell mass in the pancreas and after islet transplantation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Cutting edge: innate immunity conferred by B cells is regulated by caspase-8.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Restoration of p53 function leads to tumour regression in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Regulation of diabetes development by regulatory T cells in pancreatic islet antigen-specific TCR transgenic nonobese diabetic mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Beta cell MHC class I is a late requirement for diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

In CD4+ T-cell-induced diabetes, macrophages are the final effector cells that mediate islet beta-cell killing: studies from an acute model.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

In vivo effects of cytokines on pancreatic beta-cells in models of type I diabetes dependent on CD4(+) T lymphocytes.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Multi-parameter single-cell kinetic analysis reveals multiple modes of cell death in primary pancreatic β-cells.

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Cytotoxic T-Cells From T-Cell Receptor Transgenic NOD8.3 Mice Destroy β-Cells via the Perforin and Fas Pathways

1 reference

https://api.crossref.org/works/10.1007%2FS00125-014-3407-5

21 January 2018

Characterization of pancreatic T lymphocytes associated with beta cell destruction in the non-obese diabetic (NOD) mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the expression of heat-shock proteins and antioxidant enzymes between human and rodent pancreatic islets: implications for the pathogenesis of insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic overexpression of human Bcl-2 in islet β cells inhibits apoptosis but does not prevent autoimmune destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative determination of apoptosis of pancreatic β-cells in a murine model of type 1 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD8 T cells are not required for islet destruction induced by a CD4+ islet-specific T-cell clone

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Following a diabetogenic T cell from genesis through pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell apoptosis in an accelerated model of autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A cautionary note on the use of the TUNEL stain to determine apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25301392

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q55070749&oldid=1425112507"