(Q55462856)

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The hypermethylation of the O6-methylguanine-DNA methyltransferase gene promoter in gliomas--correlation with array comparative genome hybridization results and IDH1 mutation.

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scholarly article

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Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

The hypermethylation of the O6-methylguanine-DNA methyltransferase gene promoter in gliomas--correlation with array comparative genome hybridization results and IDH1 mutation. (English)

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Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

hypermethylation

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author name string

Katja Tuononen

1

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Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Olli Tynninen

2

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Virinder Kaur Sarhadi

3

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Anne Tyybäkinoja

4

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Mikael Lindlöf

5

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Miia Antikainen

6

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Juha Näpänkangas

7

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Ari Hirvonen

8

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Hanna Mäenpää

9

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Anders Paetau

10

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Sakari Knuutila

11

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Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

publication date

15 September 2011

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Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Genes, Chromosomes and Cancer

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Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

51

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

1

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

20-29

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

Aberrant promoter methylation of multiple genes in oligodendrogliomas and ependymomas.

1 reference

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21 January 2018

Loss of chromosome 10 is an independent prognostic factor in high-grade gliomas

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Analysis of the IDH1 codon 132 mutation in brain tumors

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https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Progenetix.net: an online repository for molecular cytogenetic aberration data

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21 January 2018

Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Correlations between O6-methylguanine DNA methyltransferase promoter methylation status, 1p and 19q deletions, and response to temozolomide in anaplastic and recurrent oligodendroglioma: a prospective GICNO study.

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21 January 2018

Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas.

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21 January 2018

Monoclonal antibody specific for IDH1 R132H mutation

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21 January 2018

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

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21 January 2018

Concurrent hypermethylation of multiple genes is associated with grade of oligodendroglial tumors.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapy

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21 January 2018

Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

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21 January 2018

Methylation of O6-methylguanine DNA methyltransferase and loss of heterozygosity on 19q and/or 17p are overlapping features of secondary glioblastomas with prolonged survival

1 reference

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21 January 2018

MGMT methylation: a marker of response to temozolomide in low-grade gliomas.

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21 January 2018

Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients

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21 January 2018

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

MGMT gene silencing and benefit from temozolomide in glioblastoma

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21 January 2018

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers

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https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

The nature and timing of specific copy number changes in the course of molecular progression in diffuse gliomas: further elucidation of their genetic "life story".

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21 January 2018

O6-methylguanine DNA methyltransferase gene promoter methylation status in gliomas and its correlation with other molecular alterations: first Indian report with review of challenges for use in customized treatment

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https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methods

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https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Genetically distinct and clinically relevant subtypes of glioblastoma defined by array-based comparative genomic hybridization (array-CGH).

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

High-resolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalances

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Correlation among pathology, genetic and epigenetic profiles, and clinical outcome in oligodendroglial tumors.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

IDH1 and IDH2 mutations, immunohistochemistry and associations in a series of brain tumors.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Significance of necrosis in grading of oligodendroglial neoplasms: a clinicopathologic and genetic study of newly diagnosed high-grade gliomas.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Frequent promoter hypermethylation and low expression of the MGMT gene in oligodendroglial tumors.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Genetic pathways to glioblastoma: a population-based study

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21 January 2018

Population-based study on incidence, survival rates, and genetic alterations of low-grade diffuse astrocytomas and oligodendrogliomas

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https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Molecular diagnostics of gliomas: state of the art.

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https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

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Analysis of loss of heterozygosity on chromosome 10 in patients with malignant astrocytic tumors: correlation with patient age and survival.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Loss of heterozygosity for loci on chromosome arms 1p and 10q in oligodendroglial tumors: relationship to outcome and chemosensitivity

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https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

Identification of genomic aberrations associated with shorter overall survival in patients with oligodendroglial tumors.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951.

1 reference

https://api.crossref.org/works/10.1002%2FGCC.20927

21 January 2018

IDH1 and IDH2 mutations are prognostic but not predictive for outcome in anaplastic oligodendroglial tumors: a report of the European Organization for Research and Treatment of Cancer Brain Tumor Group

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21 January 2018

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

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The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations

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MGMT promoter methylation in malignant gliomas: ready for personalized medicine?

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21 January 2018

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

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IDH1 and IDH2 mutations in gliomas

1 reference

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21 January 2018

Methylation Status of the O6-Methylguanine-Deoxyribonucleic Acid Methyltransferase Gene Promoter in World Health Organization Grade III Gliomas

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21 January 2018

Array comparative genomic hybridization identifies a distinct DNA copy number profile in renal cell cancer associated with hereditary leiomyomatosis and renal cell cancer

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The fundamental role of epigenetic events in cancer

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inferred from DOI database lookup

Phenotype versus genotype correlation in oligodendrogliomas and low-grade diffuse astrocytomas

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inferred from DOI database lookup

Identifiers

10.1002/GCC.20927

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

12 July 2018

http://europepmc.org/abstract/MED/21922591

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