(Q56768080)

English

Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ⁹-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsiv

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Plasma and brain pharmacokinetic profile of cannabidiol (CBD), cannabidivarine (CBDV), Δ⁹-tetrahydrocannabivarin (THCV) and cannabigerol (CBG) in rats and mice following oral and intraperitoneal administration and CBD action on obsessive-compulsiv (English)

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pharmacokinetics

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author name string

Serena Deiana

1

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Akihito Watanabe

2

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Yuki Yamasaki

3

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Naoki Amada

4

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Marlene Arthur

5

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Shona Fleming

6

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Hilary Woodcock

7

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Patricia Dorward

8

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Barbara Pigliacampo

9

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Steve Close

10

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Bettina Platt

11

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Gernot Riedel

12

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language of work or name

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publication date

February 2012

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Psychopharmacology

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219

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3

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859-73

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Antibacterial cannabinoids from Cannabis sativa: a structure-activity study

1 reference

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Boron trifluoride etherate on silica-A modified Lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells

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Endocannabinoids in the treatment of mood disorders: evidence from animal models

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21 January 2018

Blood, adipose tissue and brain levels of the cannabinoid ligands WIN-55,212 and SR-141716A after their intraperitoneal injection in mice: compound-specific and area-specific distribution within the brain

1 reference

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21 January 2018

Rimonabant: just an antiobesity drug? Current evidence on its pleiotropic effects.

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Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide

1 reference

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21 January 2018

The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice

1 reference

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21 January 2018

Do animal models of anxiety predict anxiolytic-like effects of antidepressants?

1 reference

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21 January 2018

Major tranquillizers can be distinguished from minor tranquillizers on the basis of effects on marble burying and swim-induced grooming in mice

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Delta-9-Tetrahydrocannabinol in Cancer Chemotherapy: Research Problems and Issues

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21 January 2018

The good and the bad effects of (-) trans-delta-9-tetrahydrocannabinol (Delta 9-THC) on humans

1 reference

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Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors

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21 January 2018

Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist

1 reference

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21 January 2018

A comparison of the ocular and central effects of delta 9-tetrahydrocannabinol and cannabigerol

1 reference

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21 January 2018

Intraocular pressure, ocular toxicity and neurotoxicity after administration of cannabinol or cannabigerol

1 reference

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21 January 2018

Impact of excipients on the absorption of P-glycoprotein substrates in vitro and in vivo

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21 January 2018

Fasting increases tobramycin oral absorption in mice

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21 January 2018

Melancholic features related to rimonabant

1 reference

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21 January 2018

Pleiotropic effects of rimonabant: clinical implications

1 reference

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21 January 2018

Chemical constituents of marijuana: the complex mixture of natural cannabinoids

1 reference

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21 January 2018

Delivery of cisplatin from Pluronic co-polymer systems: liposome inclusion and alginate coupling.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Delta-9-tetrahydrocannabinol pharmacokinetics

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Cannabinoids and cell fate.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Δ⁹-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

A chemotaxonomic analysis of cannabinoid variation in Cannabis (Cannabaceae).

1 reference

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21 January 2018

Structure-activity relationships in man of cannabis constituents, and homologs and metabolites of delta9-tetrahydrocannabinol

1 reference

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21 January 2018

Cannabidiol: a promising drug for neurodegenerative disorders?

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

The effect of fasting on oral acute toxicity of drugs in rats and mice

1 reference

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21 January 2018

S39-02 Antipsychotic effects of cannabidiol

1 reference

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21 January 2018

Decreases in nestlet shredding of mice by serotonin uptake inhibitors: comparison with marble burying

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma

1 reference

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21 January 2018

Distribution studies of [14C]delta-9-tetrahydrocannabinol in mice: Effect of vehicle, route of administration, and duration of treatment

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

A combined marble burying-locomotor activity test in mice: a practical screening test with sensitivity to different classes of anxiolytics and antidepressants

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Evaluation of marble-burying behavior as a model of anxiety

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

GPR55: a new member of the cannabinoid receptor clan?

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Pharmacology of cannabinoid CB1 and CB2 receptors.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Synthetic and plant-derived cannabinoid receptor antagonists show hypophagic properties in fasted and non-fasted mice

1 reference

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21 January 2018

Cannabis-based medicines in multiple sclerosis--a review of clinical studies

1 reference

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21 January 2018

Agonistic properties of cannabidiol at 5-HT1a receptors

1 reference

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21 January 2018

The orphan receptor GPR55 is a novel cannabinoid receptor

1 reference

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21 January 2018

Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors

1 reference

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21 January 2018

Antianxiety effect of cannabis: involvement of central benzodiazepine receptors

1 reference

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21 January 2018

Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac

1 reference

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21 January 2018

Species differences in blood-brain barrier transport of three positron emission tomography radioligands with emphasis on P-glycoprotein transport

1 reference

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21 January 2018

Effect of YM992, a novel antidepressant with selective serotonin re-uptake inhibitory and 5-HT 2A receptor antagonistic activity, on a marble-burying behavior test as an obsessive-compulsive disorder model

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Evidence that the plant cannabinoid Delta9-tetrahydrocannabivarin is a cannabinoid CB1 and CB2 receptor antagonist

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Examining the roles of cannabinoids in pain and other therapeutic indications: a review

1 reference

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21 January 2018

Transdermal delivery of the synthetic cannabinoid WIN 55,212-2: in vitro/in vivo correlation

1 reference

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21 January 2018

Medicinal applications of delta-9-tetrahydrocannabinol and marijuana

1 reference

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21 January 2018

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Interactions of Solutol HS 15 and Cremophor EL with plasma lipoproteins

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

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1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Preliminary Experiments on the Chemistry and Pharmacology of Cannabis

1 reference

https://api.crossref.org/works/10.1007%2FS00213-011-2415-0

21 January 2018

Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of blood disappearance and tissue distribution of [3H]cannabidiol

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Marihuana: importance of the route of administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of Solutol HS 15 on the pharmacokinetic behaviour of colchicine upon intravenous administration to male Wistar rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential transport of rat and human interleukin-1alpha across the blood-brain barrier and blood-testis barrier in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and metabolism of delta 1-tetrahydrocannabinol and other cannabinoids with emphasis on man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of cannabidiol in plasma by electron-capture gas chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of cannabidiol in dogs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-insertion into Lipid NanoCapsules (LNCs): From experimental aspects to mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single dose pharmacokinetics and bioavailability of butyryl glucosamine in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3H-Δ9-tetrahydrocannabinol, 3H-cannabinol and 3H-cannabidiol: Penetration and regional distribution in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative topical anti-inflammatory activity of cannabinoids and cannabivarins

1 reference

https://pubmed.ncbi.nlm.nih.gov/21796370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1007/S00213-011-2415-0

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