(Q57049896)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30232263%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

title

Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy (English)

1 reference

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23 April 2020

1 reference

Triggering receptor expressed on myeloid cells 2

1 reference

GOA release 2020-03-11

1 reference

1

1 reference

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23 April 2020

Maria A Telpoukhovskaia

2

1 reference

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23 April 2020

Axel Hauduc

7

1 reference

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23 April 2020

14

Katerina Akassoglou

1 reference

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23 April 2020

author name string

Lay Kodama

3

1 reference

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23 April 2020

Yaqiao Li

4

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23 April 2020

Yungui Zhou

5

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23 April 2020

David Le

6

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23 April 2020

Connor Ludwig

8

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23 April 2020

Fuying Gao

9

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23 April 2020

Claire Clelland

10

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23 April 2020

Lihong Zhan

11

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23 April 2020

Yonatan A Cooper

12

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23 April 2020

Dimitrios Davalos

13

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23 April 2020

Giovanni Coppola

15

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23 April 2020

Li Gan

16

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23 April 2020

language of work or name

English

0 references

publication date

19 September 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30232263%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

23 April 2020

published in

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23 April 2020

volume

115

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23 April 2020

issue

40

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23 April 2020

page(s)

10172-10177

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Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

23 April 2020

copyright license

start time

19 September 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau.

1 reference

12 December 2020

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

1 reference

12 December 2020

Mutations in two genes encoding different subunits of a receptor signaling complex result in an identical disease phenotype

1 reference

12 December 2020

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

1 reference

12 December 2020

ATP mediates rapid microglial response to local brain injury in vivo

1 reference

12 December 2020

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

1 reference

12 December 2020

Essential role of the microglial triggering receptor expressed on myeloid cells-2 (TREM2) for central nervous tissue immune homeostasis

1 reference

12 December 2020

Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

1 reference

12 December 2020

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

1 reference

12 December 2020

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

1 reference

12 December 2020

TREM2 Variants in Alzheimer's Disease

1 reference

12 December 2020

Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement

1 reference

12 December 2020

GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease

1 reference

12 December 2020

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

1 reference

12 December 2020

The microglial sensome revealed by direct RNA sequencing

1 reference

12 December 2020

Identification of a unique TGF-β-dependent molecular and functional signature in microglia

1 reference

12 December 2020

Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2.

1 reference

12 December 2020

An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.

1 reference

12 December 2020

The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia

1 reference

12 December 2020

TREM2 lipid sensing sustains the microglial response in an Alzheimer's disease model

1 reference

12 December 2020

TREM2 sustains microglial expansion during aging and response to demyelination

1 reference

12 December 2020

DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response

1 reference

12 December 2020

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

1 reference

12 December 2020

Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status

1 reference

12 December 2020

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

1 reference

12 December 2020

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

1 reference

12 December 2020

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

1 reference

12 December 2020

TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway

1 reference

12 December 2020

Soluble TREM2 induces inflammatory responses and enhances microglial survival.

1 reference

12 December 2020

Microglial NFκB-TNFα hyperactivation induces obsessive-compulsive behavior in mouse models of progranulin-deficient frontotemporal dementia.

1 reference

12 December 2020

TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.

1 reference

12 December 2020

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease

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12 December 2020

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

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12 December 2020

Humanized TREM2 mice reveal microglia-intrinsic and -extrinsic effects of R47H polymorphism.

1 reference

12 December 2020

The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1811411115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30232263%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30232263%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

PubMed publication ID

30232263

1 reference