(Q57457467)

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Helicobacter pylori VacA, a distinct toxin exerts diverse functionalities in numerous cells: An overview

scholarly article by Nidhi Chauhan et al published 16 October 2018 in Helicobacter

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Helicobacter pylori VacA, a distinct toxin exerts diverse functionalities in numerous cells: An overview (English)

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Barry J Marshall

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Barry Marshall

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Barry J. Marshall

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3

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Nidhi Chauhan

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Alfred Chin Yen Tay

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Utkarsh Jain

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English

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16 October 2018

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Helicobacter

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e12544

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cites work

Essential domain of receptor tyrosine phosphatase beta (RPTPbeta) for interaction with Helicobacter pylori vacuolating cytotoxin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Activation of Helicobacter pylori VacA toxin by alkaline or acid conditions increases its binding to a 250-kDa receptor protein-tyrosine phosphatase beta.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Vacuolating cytotoxin of Helicobacter pylori plays a role during colonization in a mouse model of infection

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori targets mitochondrial import and components of mitochondrial DNA replication machinery through an alternative VacA-dependent and a VacA-independent mechanisms

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Involvement of syntaxin 7 in human gastric epithelial cell vacuolation induced by the Helicobacter pylori-produced cytotoxin VacA

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Expanding allelic diversity of Helicobacter pylori vacA.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Targeting Rab GTPases to distinct membrane compartments

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori vacuolating cytotoxin inhibits T lymphocyte activation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Sphingomyelin functions as a novel receptor for Helicobacter pylori VacA.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

The Immunomodulator VacA Promotes Immune Tolerance and Persistent Helicobacter pylori Infection through Its Activities on T-Cells and Antigen-Presenting Cells

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Interaction analysis of prenylated Rab GTPase with Rab escort protein and GDP dissociation inhibitor explains the need for both regulators

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

A 12-amino-acid segment, present in type s2 but not type s1 Helicobacter pylori VacA proteins, abolishes cytotoxin activity and alters membrane channel formation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Identification of Helicobacter pylori VacA in human lung and its effects on lung cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori vacuolating cytotoxin induces apoptosis via activation of endoplasmic reticulum stress in dendritic cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

A Nonoligomerizing Mutant Form of Helicobacter pylori VacA Allows Structural Analysis of the p33 Domain.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

The relationship between Helicobacter pylori infection, the virulence genotypes of the infecting strain and gastric cancer in the African setting

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Crystal structure of the Helicobacter pylori vacuolating toxin p55 domain

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

the versatility of the Helicobacter pylori vacuolating cytotoxin vacA in signal transduction and molecular crosstalk

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Induction of apoptosis and expression of apoptosis related genes in human epithelial carcinoma cells by Helicobacter pylori VacA toxin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

The concerted action of the Helicobacter pylori cytotoxin VacA and of the v-ATPase proton pump induces swelling of isolated endosomes.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Targeting of Rab GTPases to cellular membranes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Functional properties of the p33 and p55 domains of the Helicobacter pylori vacuolating cytotoxin.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori toxin VacA is transferred to host cells via a novel contact-dependent mechanism.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Low-density lipoprotein receptor-related protein-1 (LRP1) mediates autophagy and apoptosis caused by Helicobacter pylori VacA

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Amino terminus and the first four membrane-spanning segments of the Arabidopsis K+ channel KAT1 confer inward-rectification property of plant-animal chimeric channels

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Virulent strains of Helicobacter pylori demonstrate delayed phagocytosis and stimulate homotypic phagosome fusion in macrophages

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Cytotoxicity and recognition of receptor-like protein tyrosine phosphatases, RPTPalpha and RPTPbeta, by Helicobacter pylori m2VacA.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori vacuolating cytotoxin inhibits activation-induced proliferation of human T and B lymphocyte subsets

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Genetic analysis of the Helicobacter pylori vacuolating cytotoxin: structural similarities with the IgA protease type of exported protein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori VacA induces apoptosis by accumulation of connexin 43 in autophagic vesicles via a Rac1/ERK-dependent pathway

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

PKC-dependent endocytosis of the Helicobacter pylori vacuolating cytotoxin in primary T lymphocytes.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori VacA suppresses Lactobacillus acidophilus-induced interferon beta signaling in macrophages via alterations in the endocytic pathway

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Characterization of Helicobacter pylori VacA-containing vacuoles (VCVs), VacA intracellular trafficking and interference with calcium signalling in T lymphocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Two distinctive cell binding patterns by vacuolating toxin fused with glutathione S-transferase: one high-affinity m1-specific binding and the other lower-affinity binding for variant m forms

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Phosphacan immunoreactivity is associated with perineuronal nets around parvalbumin-expressing neurones

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Cell specificity of Helicobacter pylori cytotoxin is determined by a short region in the polymorphic midregion

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Protein-tyrosine phosphatase alpha, RPTP alpha, is a Helicobacter pylori VacA receptor

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Vacuoles induced by Helicobacter pylori toxin contain both late endosomal and lysosomal markers

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori Vacuolating Toxin and Gastric Cancer.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Cellular vacuolation and mitochondrial cytochrome c release are independent outcomes of Helicobacter pylori vacuolating cytotoxin activity that are each dependent on membrane channel formation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Gastric cell apoptosis and H. pylori: has the main function of VacA finally been identified?

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Interactions between p-33 and p-55 Domains of theHelicobacter pyloriVacuolating Cytotoxin (VacA)

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Relationship between VacA Toxin and Host Cell Autophagy in Helicobacter pylori Infection of the Human Stomach: A Few Answers, Many Questions

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori VacA, a paradigm for toxin multifunctionality

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

VacA, the vacuolating cytotoxin of Helicobacter pylori, binds to multimerin 1 on human platelets

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Intoxication strategy of Helicobacter pylori VacA toxin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

An Overview of Helicobacter pylori VacA Toxin Biology

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Essential role of a GXXXG motif for membrane channel formation by Helicobacter pylori vacuolating toxin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Full-length sequence analysis of the vacA gene from cytotoxic and noncytotoxic Helicobacter pylori

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori VacA induces autophagic cell death in gastric epithelial cells via the endoplasmic reticulum stress pathway.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Cytotoxic activity in broth-culture filtrates of Campylobacter pylori

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Integrin subunit CD18 Is the T-lymphocyte receptor for the Helicobacter pylori vacuolating cytotoxin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Diversity of VacA intermediate region among Helicobacter pylori strains from several regions of the world.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori vacuolating cytotoxin (VacA) disorganizes the cytoskeletal architecture of gastric epithelial cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Helicobacter pylori counteracts the apoptotic action of its VacA toxin by injecting the CagA protein into gastric epithelial cells

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Inhibition of primary human T cell proliferation by Helicobacter pylori vacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

Tight junction disruption: Helicobacter pylori and dysregulation of the gastric mucosal barrier

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/HEL.12544

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10.1111/HEL.12544

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PubMed publication ID

30324717

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(Q57457467)

Helicobacter pylori VacA, a distinct toxin exerts diverse functionalities in numerous cells: An overview

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