(Q57799627)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

title

The Plasma NAD+ Metabolome Is Dysregulated in "Normal" Aging (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

Perminder Sachdev

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

Nady Braidy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

author name string

James Clement

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

Anne Poljak

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

language of work or name

English

0 references

publication date

23 October 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

published in

Rejuvenation Research

1 reference

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18 April 2020

volume

22

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18 April 2020

issue

2

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18 April 2020

page(s)

121-130

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

18 April 2020

RStudio

1 reference

18 June 2022

https://europepmc.org/article/PMC/6482912

inferred from PubMed Central ID database lookup

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Manipulation of a nuclear NAD+ salvage pathway delays aging without altering steady-state NAD+ levels

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Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity

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Oxidative stress evokes a metabolic adaptation that favors increased NADPH synthesis and decreased NADH production in Pseudomonas fluorescens

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CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus

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CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions

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Interferon-gamma elevates nicotinamide N-methyltransferase activity and nicotinamide level in human glioma cells

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Comparative Approach of the de novo Fatty Acid Synthesis (Lipogenesis) between Ruminant and Non Ruminant Mammalian Species: From Biochemical Level to the Main Regulatory Lipogenic Genes

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NAD(+)/NADH and skeletal muscle mitochondrial adaptations to exercise

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Extracellular NAD(+): a danger signal hindering regulatory T cells.

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Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

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Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome

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Aldehyde dehydrogenases in cellular responses to oxidative/electrophilic stress

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12 December 2020

Connexin 30 expression and frequency of connexin heterogeneity in astrocyte gap junction plaques increase with age in the rat retina

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12 December 2020

Metabolic evolution of Corynebacterium glutamicum for increased production of L-ornithine

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12 December 2020

Serum nicotinamide adenine dinucleotide levels through disease course in multiple sclerosis

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12 December 2020

Mapping NAD(+) metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence.

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12 December 2020

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.

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12 December 2020

Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism

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12 December 2020

Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

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12 December 2020

Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors

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12 December 2020

The human NAD metabolome: Functions, metabolism and compartmentalization

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12 December 2020

Differential expression of sirtuins in the aging rat brain

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12 December 2020

Serum N(1)-Methylnicotinamide Is Associated With Obesity and Diabetes in Chinese

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12 December 2020

NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

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12 December 2020

Determination of the Cytosolic NADPH/NADP Ratio in Saccharomyces cerevisiae using Shikimate Dehydrogenase as Sensor Reaction.

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12 December 2020

Niacin alleviates TRAIL-mediated colon cancer cell death via autophagy flux activation

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12 December 2020

Urinary N-methylnicotinamide and β-aminoisobutyric acid predict catch-up growth in undernourished Brazilian children

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12 December 2020

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

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12 December 2020

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.

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12 December 2020

NAD+ metabolism: Bioenergetics, signaling and manipulation for therapy.

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12 December 2020

Emerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disorders

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12 December 2020

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

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12 December 2020

N-methyl-2-pyridone-5-carboxamide (2PY)-Major Metabolite of Nicotinamide: An Update on an Old Uremic Toxin

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12 December 2020

Niacin intake and risk of skin cancer in US women and men.

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12 December 2020

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12 December 2020

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12 December 2020

Efficacy and safety of nicotinamide in haemodialysis patients: the NICOREN study

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12 December 2020

An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers.

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12 December 2020

Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule.

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12 December 2020

NAD+ supplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency.

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12 December 2020

Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes

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12 December 2020

Quantifying the cellular NAD+ metabolome using a tandem liquid chromatography mass spectrometry approach.

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12 December 2020

Identifiers

DOI

10.1089/REJ.2018.2077

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30124109%20AND%20SRC:MED&resulttype=core&format=json

18 April 2020

PubMed publication ID

30124109

1 reference