(Q59798260)

English

Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes

scientific article published on 11 May 2018

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22 March 2020

Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes (English)

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22 March 2020

molecular biology

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1 reference

based on heuristic

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pharmacokinetics

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22 March 2020

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22 March 2020

Perminder Sachdev

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22 March 2020

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Jade Berg

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22 March 2020

James Clement

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22 March 2020

Fatemeh Khorshidi

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22 March 2020

Tharusha Jayasena

6

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Europe PubMed Central

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22 March 2020

Ross Grant

7

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Europe PubMed Central

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22 March 2020

language of work or name

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11 May 2018

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22 March 2020

Antioxidants & Redox Signaling

1 reference

Europe PubMed Central

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22 March 2020

30

1 reference

Europe PubMed Central

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22 March 2020

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29634344%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

251-294

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29634344%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

Kynureninase-type enzymes and the evolution of the aerobic tryptophan-to-nicotinamide adenine dinucleotide pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic cell radiosensitizers--chemical aspects and in vitro models

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of leucine at different levels of pyridoxine on hepatic quinolinate phosphoribosyl transferase (EC2.4.2.19) and leucine aminotransferase (EC2.6.1.6) in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Public Health Reports, June 26, 1914. The etiology of pellagra. The significance of certain epidemiological observations with respect thereto

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transition metal ions induce cell growth in NRK cells synchronized in G1 by picolinic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Action of picolinic acid and structurally related pyridine carboxylic acids on quinolinic acid-induced cortical cholinergic damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tryptophan Nutrition and Metabolism: An Overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of quinolinate phosphoribosyl transferase by pyridine analogs of quinolinic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical markers for assessment of niacin status in young men: urinary and blood levels of niacin metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical markers for assessment of niacin status in young men: levels of erythrocyte niacin coenzymes and plasma tryptophan

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzyme kinetic and spectroscopic studies of inhibitor and effector interactions with indoleamine 2,3-dioxygenase. 2. Evidence for the existence of another binding site in the enzyme for indole derivative effectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lesions in the skin, intestine, and central nervous system induced by an antimetabolite of niacin

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tryptophan deficiency and picolinic acid: effect on zinc metabolism and clinical manifestations of pellagra

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereochemistry of the kynureninase reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The isolation and identification of the anti-black tongue factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The management of nicotinamide and nicotinic acid in the mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of cyclic nucleotides on purine biosynthesis and the induction of PRPP synthetase during lymphocyte activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of quinolinate phosphoribosyl-transferase in animals, plants and microorganisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect on GABA metabolism in brain of isonicotinic acid hydrazide and pyridoxine as a fuction of time after administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tryptophan load test and pyridoxine treatment in epileptic children

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is the Tryptophan Load Test a Valid Index for a Chemically-Induced Vitamin B6 Deficiency?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic Effects of Nicotinamide Administration in Rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of vitamin B6 deficiency on cytotoxic immune responses of T cells, antibodies, and natural killer cells, and phagocytosis by macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide megadosing increases hepatic poly(ADP-ribose) levels in choline-deficient rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of NAD-poly(ADP-ribose) metabolism in p53 regulation and its consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large supplements of nicotinic acid and nicotinamide increase tissue NAD+ and poly(ADP-ribose) levels but do not affect diethylnitrosamine-induced altered hepatic foci in Fischer-344 rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced GABA synthesis in pyridoxine-dependent seizures.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Picolinic acid blocks the neurotoxic but not the neuroexcitant properties of quinolinic acid in the rat brain: evidence from turning behaviour and tyrosine hydroxylase immunohistochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary niacin deficiency lowers tissue poly(ADP-ribose) and NAD+ concentrations in Fischer-344 rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide adenine dinucleotide (NADH)--a new therapeutic approach to Parkinson's disease. Comparison of oral and parenteral application

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide pharmacokinetics in patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of vitamin B6 deficiency on the conversion ratio of tryptophan to niacin

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The sequencing expression, purification, and steady-state kinetic analysis of quinolinate phosphoribosyl transferase from Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human nicotinamide N-methyltransferase gene: molecular cloning, structural characterization and chromosomal localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide pharmacokinetics in humans: effect of gastric acid inhibition, comparison of rectal vs oral administration and the use of saliva for drug monitoring

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lung poly(ADP-ribose) and NAD+ concentrations during hyperoxia and niacin deficiency in the Fischer-344 rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HPLC analysis of cyclic adenosine diphosphate ribose and adenosine diphosphate ribose: determination of NAD+ metabolites in hippocampal membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenine hydroxylase and kynureninase inhibitors as tools to study the role of kynurenine metabolites in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of nicotinamide during a five- to seven-week course of radiotherapy: pharmacokinetics, tolerance, and compliance

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinolinic acid and neurodegeneration in AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of photoimmunosuppression and photocarcinogenesis by topical nicotinamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extrachromosomal rDNA circles--a cause of aging in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histological and behavioral protection by (-)-nicotine against quinolinic acid-induced neurodegeneration in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine glial cells regenerate NAD, after peroxide-induced depletion, using either nicotinic acid, nicotinamide, or quinolinic acid as substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymology of NAD+ synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for increased de novo synthesis of NAD in immune-activated RAW264.7 macrophages: a self-protective mechanism?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of niacin on lipoprotein metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Purine nucleoside phosphorylase deficiency]

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CSF glutamate/GABA concentrations in pyridoxine-dependent seizures: etiology of pyridoxine-dependent seizures and the mechanisms of pyridoxine action in seizure control

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiological relevance of mitochondria in NAD(+) metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of recombinant human nicotinamide mononucleotide adenylyl transferase (NMNAT), a nuclear enzyme essential for NAD synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of glutamate dehydrogenase by reversible ADP-ribosylation in mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinolinic acid accumulation during neuroinflammation. Does it imply excitotoxicity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular nicotinamide adenine dinucleotide induces t cell apoptosis in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of nicotinamide on the radiosensitivity of normal and goitrous thyroid in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin deficiency decreases bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A volumetric biochemical niacin flush-based index that noninvasively detects fatty acid deficiency in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple conformations of NAD and NADH when bound to human cytosolic and mitochondrial aldehyde dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The isolation and identification of the anti-black tongue factor. 1937

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implications of the kynurenine pathway and quinolinic acid in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PNP (purine nucleoside phosphorylase) deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety of stabilized, orally absorbable, reduced nicotinamide adenine dinucleotide (NADH): a 26-week oral tablet administration of ENADA/NADH for chronic toxicity study in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of picolinic and quinolinic acids following enzymatic oxidation of 3-hydroxyanthranilic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Diets of cereals & other vegetable proteins & cutaneous pellegra in our country.]

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HYDROXYKYNURENINURIA: A CASE OF ABNORMAL TRYPTOPHAN METABOLISM PROBABLY DUE TO A DEFICIENCY OF KYNURENINASE

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engineering and Characterization of a NADPH-Utilizing Cytochrome b5 Reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pellagra: dermatitis, dementia, and diarrhea

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymology of NAD+ homeostasis in man.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase-1-mediated cell death in astrocytes requires NAD+ depletion and mitochondrial permeability transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial of intervention before the onset of type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD38 is expressed on human mature monocyte-derived dendritic cells and is functionally involved in CD83 expression and IL-12 induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accumulation of quinolinic acid with neuroinflammation: does it mean excitotoxicity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is sensitization with nicotinamide and carbogen dependent on nicotinamide concentration at the time of irradiation?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide relaxes vascular smooth muscle by inhibiting myosin light chain kinase-dependent signaling pathways: implications for anticancer efficacy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autotoxicity, methylation and a road to the prevention of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of human SIRT1 activation by resveratrol

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide and mitochondrial biogenesis: a key to long-term regulation of cellular metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous determination of myristyl nicotinate, nicotinic acid, and nicotinamide in rabbit plasma by liquid chromatography-tandem mass spectrometry using methyl ethyl ketone as a deproteinization solvent

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The antioxidant function of the p53 tumor suppressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide increases thyroid radiosensitivity by stimulating nitric oxide synthase expression and the generation of organic peroxides

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The etiology of pellagra. 1914.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased cADPR and increased NAD+ in the Cd38-/- mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of metabolic fates of nicotinamide, NAD+ and NADH administered orally and intraperitoneally; characterization of oral NADH

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose): novel functions for an old molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamine-dependent NAD+Synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear ADP-ribosylation reactions in mammalian cells: where are we today and where are we going?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A contribution to the chemistry of proteids: Part I. A preliminary study of a hitherto undescribed product of tryptic digestion

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential susceptibility to striatal neurodegeneration induced by quinolinic acid and kainate in inbred, outbred and hybrid mouse strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acid receptor subtypes and their ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD38 is critical for social behaviour by regulating oxytocin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide 2-fluoroadenine dinucleotide unmasks the NAD+ glycohydrolase activity of Aplysia californica adenosine 5'-diphosphate ribosyl cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Water maze performance in young male Long-Evans rats is inversely affected by dietary intakes of niacin and may be linked to levels of the NAD+ metabolite cADPR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol stimulates AMP kinase activity in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt1 regulates aging and resistance to oxidative stress in the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical radiosensitizers for use in radiotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian Sir2-related protein (SIRT) 2-mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: a crucial role of tubulin deacetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of cellular NAD levels by nicotinic acid and involvement of nicotinic acid phosphoribosyltransferase in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin in cardiovascular prevention: mechanisms, efficacy, and safety.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide N-methyltransferase upregulation inversely correlates with lymph node metastasis in oral squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide riboside kinase structures reveal new pathways to NAD+

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 deacetylates and positively regulates the nuclear receptor LXR

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional localization of two poly(ADP-ribose)-degrading enzymes to the mitochondrial matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin restriction upregulates NADPH oxidase and reactive oxygen species (ROS) in human keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acid (niacin) receptor agonists: will they be useful therapeutic agents?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinolinic acid induced neurodegeneration in the striatum: a combined in vivo and in vitro analysis of receptor changes and microglia activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of niacin

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol directly targets COX-2 to inhibit carcinogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular NAD and ATP: Partners in immune cell modulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin deficiency causes oxidative stress in rat bone marrow cells but not through decreased NADPH or glutathione status

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin supplementation decreases the incidence of alkylation-induced nonlymphocytic leukemia in Long-Evans rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt1 protects against oxidative stress-induced renal tubular cell apoptosis by the bidirectional regulation of catalase expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological inhibition of nicotinamide phosphoribosyltransferase/visfatin enzymatic activity identifies a new inflammatory pathway linked to NAD

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promotion of cellular NAD(+) anabolism: therapeutic potential for oxidative stress in ageing and Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin inhibits vascular oxidative stress, redox-sensitive genes, and monocyte adhesion to human aortic endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide adenine dinucleotide phosphate oxidase and diabetes: vascular implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT2 is a negative regulator of anoxia-reoxygenation tolerance via regulation of 14-3-3 zeta and BAD in H9c2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin increases HDL by reducing hepatic expression and plasma levels of cholesteryl ester transfer protein in APOE*3Leiden.CETP mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An outbreak of pellegra syndrome in a rural area of Bengal

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD38 and CD157 ectoenzymes mark cell subsets in the human corneal limbus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of NAD in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NMN/NaMN adenylyltransferase (NMNAT) protein family.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of nicotinamide on experimental induced diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin status and treatment-related leukemogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

'When an old rat smells a cat': A decline in defense-related, but not accessory olfactory, Fos expression in aged rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dementia with features of Alzheimer's disease and HIV-associated dementia in an elderly man with AIDS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinic acid-mediated activation of both membrane and nuclear receptors towards therapeutic glucocorticoid mimetics for treating multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of hypoxia-inducible factor 2alpha signaling by the stress-responsive deacetylase sirtuin 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caloric restriction delays disease onset and mortality in rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The excitotoxin quinolinic acid induces tau phosphorylation in human neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytic poly(ADP-ribose) polymerase-1 activation leads to bioenergetic depletion and inhibition of glutamate uptake capacity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin status impacts chromatin structure.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide overload may play a role in the development of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The secret life of NAD+: an old metabolite controlling new metabolic signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Anti-aging studies on the senescence accelerated mouse (SAM) strains].

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase 1 at the crossroad of metabolic stress and inflammation in aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinolinate phosphoribosyl transferase, a key enzyme in de novo NAD(+) synthesis, suppresses spontaneous cell death by inhibiting overproduction of active-caspase-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Malnutrition and pellegra in South Africa

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt1 activation protects the mouse renal medulla from oxidative injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wallerian degeneration, wld(s), and nmnat

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC-1 alpha regulates expression of myocardial mitochondrial antioxidants and myocardial oxidative stress after chronic systolic overload

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating and local visfatin/Nampt/PBEF levels in spontaneously hypertensive rats, stroke-prone spontaneously hypertensive rats and Wistar-Kyoto rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of nicotinamide in DNA damage, mutagenesis, and DNA repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Minocycline protects cardiac myocytes against simulated ischemia–reperfusion injury by inhibiting poly(ADP-ribose) polymerase-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein cleavage-dependent and -independent axonal degeneration programs share a common nicotinamide mononucleotide adenylyltransferase 1-sensitive pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factors and the response to hypoxic stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deficiency or inhibition of CD73 protects in mild kidney ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT1 modulation as a novel approach to the treatment of diseases of aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT2 regulates NF-κB dependent gene expression through deacetylation of p65 Lys310

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resveratrol commonly displays hormesis: occurrence and biomedical significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of the expression of NMDA receptors in human astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy of controlled-release niacin in treatment of metabolic syndrome: Correlation to surrogate markers of atherosclerosis, vascular reactivity, and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide mononucleotide adenylyltransferase is a stress response protein regulated by the heat shock factor/hypoxia-inducible factor 1alpha pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMNAT expression and its relation to NAD metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD blocks high glucose induced mesangial hypertrophy via activation of the sirtuins-AMPK-mTOR pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of human nicotinate phosphoribosyltransferase: Kinetic studies, structure prediction and functional analysis by site-directed mutagenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determining the extremes of the cellular NAD(H) level by using an Escherichia coli NAD(+)-auxotrophic mutant

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Kynurenine Pathway Inhibition on NAD Metabolism and Cell Viability in Human Primary Astrocytes and Neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin status and genomic instability in bone marrow cells; mechanisms favoring the progression of leukemogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced coupling of oxidative phosphorylation in vivo precedes electron transport chain defects due to mild oxidative stress in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The PRPP synthetase spectrum: what does it demonstrate about nucleotide syndromes?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin requirements for genomic stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The historical evolution of thought regarding multiple micronutrient nutrition

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormesis does not make sense except in the light of TOR-driven aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Research progress on nicotinamide phosphoribosyl transferase involved in aging and age-related diseases]

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral nicotinamide reduces actinic keratoses in phase II double-blinded randomized controlled trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD+ metabolism and oxidative stress: the golden nucleotide on a crown of thorns.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical identification and crystal structure of kynurenine formamidase from Drosophila melanogaster

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of HIV-1 tat-induced transactivation and apoptosis by the divalent metal chelators, fusaric acid and picolinic acid-implications for HIV-1 dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide pretreatment protects cardiomyocytes against hypoxia-induced cell death by improving mitochondrial stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirtuin 1 and sirtuin 3: physiological modulators of metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-associated changes in oxidative stress and NAD+ metabolism in human tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of PARP by oxidative stress induced by β-amyloid: implications for Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in the redox state and endogenous fluorescence of in vivo human skin due to intrinsic and photo-aging, measured by multiphoton tomography with fluorescence lifetime imaging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLD(S)-mediated axon protection independent of axonal mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo multiphoton NADH fluorescence reveals depth-dependent keratinocyte metabolism in human skin

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide downregulates gene expression of interleukin-6, interleukin-10, monocyte chemoattractant protein-1, and tumour necrosis factor-α gene expression in HaCaT keratinocytes after ultraviolet B irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of quinolinic acid, an intermediate in the kynurenine pathway, for utilization in NAD+ biosynthesis in the yeast Saccharomyces cerevisiae.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Connexin 30 expression and frequency of connexin heterogeneity in astrocyte gap junction plaques increase with age in the rat retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of tryptophan 2,3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hallmarks of aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The discovery of the vitamins

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diversification of NAD biological role: the importance of location

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic disturbances and defects in insulin secretion in rats with streptozotocin-nicotinamide-induced diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial complex I deficiency increases protein acetylation and accelerates heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD38 controls the innate immune response against Listeria monocytogenes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The enzymology of cytosolic pyrimidine 5'-nucleotidases: functional analysis and physiopathological implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and ageing

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT4 prevents hypoxia-induced apoptosis in H9c2 cardiomyoblast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic characterization of a Sirt5 deficient mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Axonal protection by Nmnat3 overexpression with involvement of autophagy in optic nerve degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide treatment reduces the levels of oxidative stress, apoptosis, and PARP-1 activity in Aβ(1-42)-induced rat model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Network beyond IDO in psychiatric disorders: revisiting neurodegeneration hypothesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide pre-treatment ameliorates NAD(H) hyperoxidation and improves neuronal function after severe hypoxia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and mechanism of kynureninase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of oxidative stress as an anticancer strategy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide improves glucose metabolism and affects the hepatic NAD-sirtuin pathway in a rodent model of obesity and type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mapping NAD(+) metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical evidence of mitochondrial nicotinamide adenine dinucleotide as an effective alarm parameter under hypoxia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Sirt1 during the ageing process: relevance to protection of synapses in the brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytomegalovirus-specific responses of CD38⁺ memory T cells are skewed towards IFN-γ and dissociated from CD154 in HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pellagra and alcoholism: a biochemical perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling pathway cross talk in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted, LCMS-based Metabolomics for Quantitative Measurement of NAD(+) Metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The evolving role of the NAD+/nicotinamide metabolome in skin homeostasis, cellular bioenergetics, and aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of Caenorhabditis elegans FOXO/DAF-16 modulates lifespan.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD+ and SIRT3 control microtubule dynamics and reduce susceptibility to antimicrotubule agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of inhibition of the human sirtuin enzyme SIRT3 by nicotinamide: computational and experimental studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-B cell colony enhancing factor induces Nampt-dependent translocation of the insulin receptor out of lipid microdomains in A549 lung epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic regulation of histone post-translational modifications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The renoprotective effect of curcumin in cisplatin-induced nephrotoxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirtuin 3-dependent mitochondrial dynamic improvements protect against acute kidney injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large amounts of picolinic acid are lethal but small amounts increase the conversion of tryptophan-nicotinamide in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutritional energy stimulates NAD+ production to promote tankyrase-mediated PARsylation in insulinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PARP-1 involvement in neurodegeneration: A focus on Alzheimer's and Parkinson's diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Niacin metabolism and indoleamine 2,3-dioxygenase activation in malnourished patients with flaky paint dermatosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide Riboside Ameliorates Hepatic Metaflammation by Modulating NLRP3 Inflammasome in a Rodent Model of Type 2 Diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of formulation design on niacin therapeutics: mechanism of action, metabolism, and drug delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of sirtuins in the aging rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel protein-protein interactions of TPPII, p53, and SIRT7.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Green Tea Polyphenols Attenuate High-Fat Diet-Induced Renal Oxidative Stress through SIRT3-Dependent Deacetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NNMT: A Bad Actor in Fat Makes Good in Liver.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NADPH-generating systems in bacteria and archaea

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Novel Continuous Assay for the Deacylase Sirtuin 5 and Other Deacetylases

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Letter to the Editor: High Serum N(1)-Methylnicotinamide in Obesity and Diabetes: A Consequence of Excess Nicotinamide?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation, Release, and Uptake of the NAD Precursor Nicotinic Acid Riboside by Human Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the cardiac succinylome and its role in ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calorie restriction for optimal cardiovascular aging: the weight of evidence

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wernicke encephalopathy and pellagra in an alcoholic and malnourished patient

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAMPT as a Therapeutic Target against Stroke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NADP(+)-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

True Niacin Deficiency in Quinolinic Acid Phosphoribosyltransferase (QPRT) Knockout Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intakes of folate, vitamin B6 and B12 and risk of depression in community-dwelling older adults: the Quebec Longitudinal Study on Nutrition and Aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extensive regulation of nicotinate phosphoribosyltransferase (NAPRT) expression in human tissues and tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigallocatechin-3-gallate induces oxidative phosphorylation by activating cytochrome c oxidase in human cultured neurons and astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD⁺ in aging, metabolism, and neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenine pathway metabolites and enzymes involved in redox reactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety of two-year caloric restriction in non-obese healthy individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide) as an essential gene for colorectal cancer (CRCs) cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial protein hyperacetylation in the failing heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parp mutations protect against mitochondrial dysfunction and neurodegeneration in a PARKIN model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleolar PARP-1 Expression Is Decreased in Alzheimer's Disease: Consequences for Epigenetic Regulation of rDNA and Cognition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT4 accelerates Ang II-induced pathological cardiac hypertrophy by inhibiting manganese superoxide dismutase activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection effect of nicotinamide on cardiomyoblast hypoxia/re-oxygenation injury: study of cellular mitochondrial metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Action of nicotinic acid on the reversion of hypoxic-inflammatory link on 3T3-L1 adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SIRT2 mediates NADH-induced increases in Nrf2, GCL, and glutathione by modulating Akt phosphorylation in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenine Aminotransferase Isozyme Inhibitors: A Review

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NAD(+) precursor nicotinamide riboside decreases exercise performance in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD38 Deficiency Protects the Heart from Ischemia/Reperfusion Injury through Activating SIRT1/FOXOs-Mediated Antioxidative Stress Pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioenergetic Impairment in Animal and Cellular Models of Alzheimer's Disease: PARP-1 Inhibition Rescues Metabolic Dysfunctions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-Induced Genotype Switch in Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase Through the Up-Regulation of Cytidine Deaminase Regulates Postoperative Adhesion Development

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Circadian NAD+ Metabolism: Impact on Chromatin Remodeling and Aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caloric restriction improves health and survival of rhesus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of NAD+ and mitochondrial sirtuins in cardiac and renal diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of exogenous vitamins A, C, and E and NADH supplementation on proliferation, cytokines release, and cell redox status of lymphocytes from healthy aged subjects.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The NAD+ precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenine pathway metabolism and neuroinflammatory disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of concomitant administration of three different antidepressants with vitamin B6 on depression and obsessive compulsive disorder in mice models

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and functional characterization of quinolinic acid phosphoribosyl transferase (QPT) gene of Nicotiana tabacum.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide N-Methyltransferase: More Than a Vitamin B3 Clearance Enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD38 promotes angiotensin II-induced cardiac hypertrophy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide mononucleotide inhibits JNK activation to reverse Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hormesis: a fundamental concept in biology

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased quinolinic acid in peripheral mononuclear cells in Alzheimer's dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirtuins and DNA damage repair: SIRT7 comes to play

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicotinamide is an inhibitor of SIRT1 in vitro, but can be a stimulator in cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Nampt expression by transcriptional coactivator NCOA6 in pancreatic β-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NMNAT: It's an NAD+ synthase… It's a chaperone… It's a neuroprotector.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vasorelaxing Action of the Kynurenine Metabolite, Xanthurenic Acid: The Missing Link in Endotoxin-Induced Hypotension?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinolinic carboxylic acid derivatives as potential multi-target compounds for neurodegeneration: monoamine oxidase and cholinesterase inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New Challenges to Study Heterogeneity in Cancer Redox Metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD+ in Aging: Molecular Mechanisms and Translational Implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How does hormesis impact biology, toxicology, and medicine?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advanced glycation end products reduce the calcium transient in cardiomyocytes by increasing production of reactive oxygen species and nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29634344

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1089/ARS.2017.7269

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29634344%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29634344%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29634344%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

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