(Q57987207)

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Molecular Basis of Ligand Recognition by Integrin α5β1

scientific article published in Journal of Biological Chemistry

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scholarly article

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5 November 2019

Molecular basis of ligand recognition by integrin alpha5beta 1. II. Specificity of arg-gly-Asp binding is determined by Trp157 OF THE alpha subunit (English)

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5 November 2019

Yoshikazu Takada

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5 November 2019

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5 November 2019

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J D Humphries

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5 November 2019

J A Askari

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5 November 2019

X P Zhang

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5 November 2019

M J Humphries

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5 November 2019

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1 July 2000

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5 November 2019

Journal of Biological Chemistry

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5 November 2019

275

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5 November 2019

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5 November 2019

20337-20345

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5 November 2019

Integrins: versatility, modulation, and signaling in cell adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Definition of an unexpected ligand recognition motif for alphav beta6 integrin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Isolation of a highly specific ligand for the alpha 5 beta 1 integrin from a phage display library.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Phage libraries displaying cyclic peptides with different ring sizes: ligand specificities of the RGD-directed integrins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Homology modelling of integrin EF-hands. Evidence for widespread use of a conserved cation-binding site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

The structure of cell-adhesion molecules.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Structural basis of integrin-mediated signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Multiple loop structures critical for ligand binding of the integrin alpha4 subunit in the upper face of the beta-propeller mode 1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Differential effects of integrin alpha chain mutations on invasin and natural ligand interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Identification of Amino Acid Residues That Form Part of the Ligand-binding Pocket of Integrin α5β1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Ligand binding to integrin alphaIIbbeta3 is dependent on a MIDAS-like domain in the beta3 subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

A structure prediction for the ligand-binding region of the integrin beta subunit: evidence for the presence of a von Willebrand factor A domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Critical residues for ligand binding in an I domain-like structure of the integrin beta1 subunit.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Evidence that the integrin beta3 and beta5 subunits contain a metal ion-dependent adhesion site-like motif but lack an I domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Disulfide bond formation in peptides by dimethyl sulfoxide. Scope and applications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

The Inhibitory Anti-β1 Integrin Monoclonal Antibody 13 Recognizes an Epitope That Is Attenuated by Ligand Occupancy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Requirement for the synergy site for cell adhesion to fibronectin depends on the activation state of integrin alpha 5 beta 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Regulation of integrin alpha 5 beta 1-fibronectin interactions by divalent cations. Evidence for distinct classes of binding sites for Mn2+, Mg2+, and Ca2+.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Fine mapping of inhibitory anti-alpha5 monoclonal antibody epitopes that differentially affect integrin-ligand binding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Isolation and characterization of Chinese hamster ovary cell variants deficient in the expression of fibronectin receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Freezing adhesion molecules in a state of high-avidity binding blocks eosinophil migration.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

A hot spot of binding energy in a hormone-receptor interface

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

pi-Stacking interactions. Alive and well in proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Anatomy of hot spots in protein interfaces

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

RGD and other recognition sequences for integrins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Localization of an Arg-Gly-Asp recognition site within an integrin adhesion receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Mapping the integrin alpha V beta 3-ligand interface by photoaffinity cross-linking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Cell adhesion in vascular biology. New insights into integrin-ligand interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Molecular Basis of Ligand Recognition by Integrin α5β1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Alpha 3 beta 1 adhesion to laminin-5 and invasin: critical and differential role of integrin residues clustered at the boundary between alpha 3 N-terminal repeats 2 and 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

A two-amino acid insertion in the Cys146- Cys167 loop of the alphaIIb subunit is associated with a variant of Glanzmann thrombasthenia. Critical role of Asp163 in ligand binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Changing Ligand Specificities of αvβ1 and αvβ3 Integrins by Swapping a Short Diverse Sequence of the β Subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Identification of a region in the integrin beta3 subunit that confers ligand binding specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Integrin antagonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Regulation of the extracellular ligand binding activity of integrins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Identifying the putative metal ion-dependent adhesion site in the beta2 (CD18) subunit required for alphaLbeta2 and alphaMbeta2 ligand interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Peptide ligands can bind to distinct sites in integrin alphaIIbbeta3 and elicit different functional responses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M000568200

21 January 2018

Identifiers

10.1074/JBC.M000568200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764747%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764747%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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