(Q58043206)

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Age-Dependent Association of the Polymorphisms in the Mitochondria-Shaping Gene, OPA1, With Blood Pressure and Hypertension in Korean Population

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scholarly article

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Age-Dependent Association of the Polymorphisms in the Mitochondria-Shaping Gene, OPA1, With Blood Pressure and Hypertension in Korean Population (English)

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6

object named as

Maris Laan

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2

object named as

Siim Sõber

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4

object named as

Elin Org

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Hyun-Seok Jin

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author name string

Kyung-Won Hong

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Bo-Young Kim

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Bermseok Oh

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Seon-Yong Jeong

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publication date

1 October 2011

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Journal of Clinical Hypertension

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24

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10

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1127-1135

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Molecular mechanisms of human hypertension

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Genetic architecture of complex traits predisposing to nephropathy: hypertension

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A review of the genetics of essential hypertension

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Genome-wide association study of blood pressure and hypertension

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Genome-wide association study identifies eight loci associated with blood pressure

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The role of mitochondrial genome in essential hypertension in a Chinese Han population

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The putative role of mitochondrial dysfunction in hypertension

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Mitochondria: more than just a powerhouse

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Mitochondrial fusion and fission in mammals

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The machines that divide and fuse mitochondria

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Regulation of mitochondrial fusion and division

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Mitochondrial fusion and division: Regulation and role in cell viability

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Mitochondrial dynamics and Ca2+ signaling

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Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology

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Mitochondria, nitric oxide, and cardiovascular dysfunction.

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Mitochondrial dysfunction and mitochondrial-produced reactive oxygen species: new targets for neurogenic hypertension?

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Mitochondrial Ca2+ and the heart

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Mitochondrial morphology and cardiovascular disease

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Mitochondrial fission and fusion and their roles in the heart

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HSG/Mfn2 gene polymorphism and essential hypertension: a case-control association study in Chinese.

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A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits

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Genetic effect on blood pressure is modulated by age: the Hypertension Genetic Epidemiology Network Study.

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Clinical Advisory Statement. Importance of systolic blood pressure in older Americans

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Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations

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Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study

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Molecular mechanisms of angiotensin II-mediated mitochondrial dysfunction: linking mitochondrial oxidative damage and vascular endothelial dysfunction

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A cluster of metabolic defects caused by mutation in a mitochondrial tRNA.

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Functions and dysfunctions of mitochondrial dynamics

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Mitochondrial dysfunction and age.

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Oxidative damage and mutation to mitochondrial DNA and age-dependent decline of mitochondrial respiratory function

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Prevalence of Hypertension in the US Adult Population : Results From the Third National Health and Nutrition Examination Survey, 1988-1991

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Heterozygous mutation of Drosophila Opa1 causes the development of multiple organ abnormalities in an age-dependent and organ-specific manner

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Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production.

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OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

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The OPA1 gene polymorphism is associated with normal tension and high tension glaucoma.

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Blood pressure, perfusion pressure, and glaucoma.

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Mitochondrial OPA1, apoptosis, and heart failure

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The Foxa family of transcription factors in development and metabolism

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Mitochondrial fission in apoptosis

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Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

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The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity.

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Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2

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PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites

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10.1038/AJH.2011.131

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