(Q58111146)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

title

Many Cells Make Life Work-Multicellularity in Stem Cell-Based Cardiac Disease Modelling (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

Human Induced Pluripotent Stem Cells

1 May 2020

main subject

cardiomyocyte

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1 reference

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

author name string

Brian X Wang

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

Cesare M N Terracciano

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

language of work or name

English

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publication date

27 October 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Molecular Sciences

1 May 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

1 May 2020

page(s)

3361

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copyright license

start time

27 October 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure

1 reference

12 December 2020

Structural remodeling of cardiac myocytes in patients with ischemic cardiomyopathy

1 reference

12 December 2020

Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium

1 reference

12 December 2020

Creating animal models of genetic disease.

1 reference

12 December 2020

Cell cultures of adult cardiomyocytes as models of the myocardium

1 reference

12 December 2020

Animal models of human genetic diseases

1 reference

12 December 2020

Connexins in mammalian heart function

1 reference

12 December 2020

The organization of the human gene NCX1 encoding the sodium-calcium exchanger

1 reference

12 December 2020

Embryonic stem cell lines derived from human blastocysts

1 reference

12 December 2020

Concordance of the toxicity of pharmaceuticals in humans and in animals

1 reference

12 December 2020

Adult rabbit cardiomyocytes undergo hibernation-like dedifferentiation when co-cultured with cardiac fibroblasts

1 reference

12 December 2020

Metabolic gene expression in fetal and failing human heart

1 reference

12 December 2020

Regulation of Kv4.3 current by KChIP2 splice variants: a component of native cardiac I(to)?

1 reference

12 December 2020

Endothelial dysfunction

1 reference

12 December 2020

Endothelial-cardiomyocyte interactions in cardiac development and repair

1 reference

12 December 2020

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

12 December 2020

Dynamic changes in conduction velocity and gap junction properties during development of pacing-induced heart failure

1 reference

12 December 2020

Regional and tissue specific transcript signatures of ion channel genes in the non-diseased human heart

1 reference

12 December 2020

Generation of germline-competent induced pluripotent stem cells

1 reference

12 December 2020

Heart failure and nephropathy: catastrophic and interrelated complications of diabetes

1 reference

12 December 2020

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

12 December 2020

Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts

1 reference

12 December 2020

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

1 reference

12 December 2020

Evidence for cardiomyocyte renewal in humans

1 reference

12 December 2020

Influence of renal function on the effects of early revascularization in non-ST-elevation myocardial infarction: data from the Swedish Web-System for Enhancement and Development of Evidence-Based Care in Heart Disease Evaluated According to Recommen

1 reference

12 December 2020

Cardiomyocyte differentiation of human induced pluripotent stem cells

1 reference

12 December 2020

Origin of cardiac fibroblasts and the role of periostin

1 reference

12 December 2020

The first reported generation of human induced pluripotent stem cells (iPS cells) and iPS cell-derived cardiomyocytes in the Netherlands

1 reference

12 December 2020

Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome

1 reference

12 December 2020

Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening.

1 reference

12 December 2020

Patient-specific induced pluripotent stem-cell models for long-QT syndrome

1 reference

12 December 2020

Extracellular matrix roles during cardiac repair.

1 reference

12 December 2020

Dedifferentiation and proliferation of mammalian cardiomyocytes

1 reference

12 December 2020

A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects

1 reference

12 December 2020

Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome

1 reference

12 December 2020

An improved isolation procedure for adult mouse cardiomyocytes

1 reference

12 December 2020

Animal models of human genetic diseases: do they need to be faithful to be useful?

1 reference

12 December 2020

Growth of engineered human myocardium with mechanical loading and vascular coculture

1 reference

12 December 2020

Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimulation

1 reference

12 December 2020

Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture

1 reference

12 December 2020

In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells

1 reference

12 December 2020

Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility

1 reference

12 December 2020

Determinants of the decline in mortality from acute myocardial infarction in England between 2002 and 2010: linked national database study

1 reference

12 December 2020

Optical imaging of voltage and calcium in cardiac cells & tissues

1 reference

12 December 2020

Modification of a volume-overload heart failure model to track myocardial remodeling and device-related reverse remodeling

1 reference

12 December 2020

Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure

1 reference

12 December 2020

Derivation and cardiomyocyte differentiation of induced pluripotent stem cells from heart failure patients

1 reference

12 December 2020

Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling.

1 reference

12 December 2020

Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease

1 reference

12 December 2020

Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study

1 reference

12 December 2020

Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels

1 reference

12 December 2020

Modeling supravalvular aortic stenosis syndrome with human induced pluripotent stem cells.

1 reference

12 December 2020

Cardiac fibroblasts, fibrosis and extracellular matrix remodeling in heart disease

1 reference

12 December 2020

Derivation and maturation of synthetic and contractile vascular smooth muscle cells from human pluripotent stem cells

1 reference

12 December 2020

Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia.

1 reference

12 December 2020

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells

1 reference

12 December 2020

Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified by whole exome sequencing.

1 reference

12 December 2020

Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs

1 reference

12 December 2020

Regulatory T cells contribute to rosuvastatin-induced cardioprotection against ischemia-reperfusion injury

1 reference

12 December 2020

The pathogenesis of cardiac fibrosis.

1 reference

12 December 2020

Comparison of electrophysiological data from human-induced pluripotent stem cell-derived cardiomyocytes to functional preclinical safety assays

1 reference

12 December 2020

A brief history of animal modeling

1 reference

12 December 2020

Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

1 reference

12 December 2020

Stem cell therapy for electrophysiological disorders.

1 reference

12 December 2020

Functional vascular endothelium derived from human induced pluripotent stem cells.

1 reference

12 December 2020

Myosin light chain 2-based selection of human iPSC-derived early ventricular cardiac myocytes

1 reference

12 December 2020

Mechanistic basis of excitation-contraction coupling in human pluripotent stem cell-derived ventricular cardiomyocytes revealed by Ca2+ spark characteristics: direct evidence of functional Ca2+-induced Ca2+ release

1 reference

12 December 2020

Dynamic cell-cell and cell-ECM interactions in the heart

1 reference

12 December 2020

Remodeling of the mononuclear phagocyte network underlies chronic inflammation and disease progression in heart failure: critical importance of the cardiosplenic axis

1 reference

12 December 2020

Mechanisms of load dependency of myocardial ischemia reperfusion injury

1 reference

12 December 2020

The vascular endothelium and human diseases

1 reference

12 December 2020

Cardiomyocyte culture - an update on the in vitro cardiovascular model and future challenges.

1 reference

12 December 2020

Engineering adolescence: maturation of human pluripotent stem cell-derived cardiomyocytes

1 reference

12 December 2020

Dynamic changes in myocardial matrix and relevance to disease: translational perspectives

1 reference

12 December 2020

An induced pluripotent stem cell model of hypoplastic left heart syndrome (HLHS) reveals multiple expression and functional differences in HLHS-derived cardiac myocytes

1 reference

12 December 2020

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

1 reference

12 December 2020

Isolation and culture of adult mouse cardiomyocytes for cell signaling and in vitro cardiac hypertrophy

1 reference

12 December 2020

Chemically defined generation of human cardiomyocytes

1 reference

12 December 2020

A systemic evaluation of cardiac differentiation from mRNA reprogrammed human induced pluripotent stem cells.

1 reference

12 December 2020

Genomic editing tools to model human diseases with isogenic pluripotent stem cells

1 reference

12 December 2020

Peripheral neuropathy may be a potential risk of cardiovascular disease in diabetes mellitus

1 reference

12 December 2020

Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system

1 reference

12 December 2020

hERG 1b is critical for human cardiac repolarization

1 reference

12 December 2020

Human induced pluripotent stem cell-derived B lymphocytes express sIgM and can be generated via a hemogenic endothelium intermediate.

1 reference

12 December 2020

Induced pluripotent stem cell-derived vascular smooth muscle cells: methods and application

1 reference

12 December 2020

Functional crosstalk between cardiac fibroblasts and adult cardiomyocytes by soluble mediators.

1 reference

12 December 2020

Action potential morphology of human induced pluripotent stem cell-derived cardiomyocytes does not predict cardiac chamber specificity and is dependent on cell density

1 reference

12 December 2020

Role of lymphocytes in myocardial injury, healing, and remodeling after myocardial infarction

1 reference

12 December 2020

Functional and Electrical Integration of Induced Pluripotent Stem Cell-Derived Cardiomyocytes in a Myocardial Infarction Rat Heart.

1 reference

12 December 2020

Role of innate and adaptive immune mechanisms in cardiac injury and repair

1 reference

12 December 2020

Neuron-derived neurotrophic factor ameliorates adverse cardiac remodeling after experimental myocardial infarction

1 reference

12 December 2020

Differentiation of Human Neural Stem Cells into Motor Neurons Stimulates Mitochondrial Biogenesis and Decreases Glycolytic Flux

1 reference

12 December 2020

Functional Characterization and Comparison of Intercellular Communication in Stem Cell-Derived Cardiomyocytes.

1 reference

12 December 2020

Maturation-Based Model of Arrhythmogenic Right Ventricular Dysplasia Using Patient-Specific Induced Pluripotent Stem Cells

1 reference

12 December 2020

Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories.

1 reference

12 December 2020

Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes

1 reference

12 December 2020

Crosstalk of cardiomyocytes and fibroblasts in co-cultures.

1 reference

12 December 2020

Human induced pluripotent stem cell-derived cardiomyocytes: insights into molecular, cellular, and functional phenotypes

1 reference

12 December 2020

Generating induced pluripotent stem cell derived endothelial cells and induced endothelial cells for cardiovascular disease modelling and therapeutic angiogenesis

1 reference

12 December 2020

Ion Channels in the Heart

1 reference

12 December 2020

Transcriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells

1 reference

12 December 2020

Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells

1 reference

12 December 2020

Concise Review: Pluripotent Stem Cell-Derived Cardiac Cells, A Promising Cell Source for Therapy of Heart Failure: Where Do We Stand?

1 reference

12 December 2020

Robust generation and expansion of skeletal muscle progenitors and myocytes from human pluripotent stem cells.

1 reference

12 December 2020

Engineering large animal models of human disease

1 reference

12 December 2020

In vitro cardiac tissue models: Current status and future prospects.

1 reference

12 December 2020

Chemically Defined Culture and Cardiomyocyte Differentiation of Human Pluripotent Stem Cells

1 reference

12 December 2020

Cardiomyocyte and Vascular Smooth Muscle-Independent 11β-Hydroxysteroid Dehydrogenase 1 Amplifies Infarct Expansion, Hypertrophy, and the Development of Heart Failure After Myocardial Infarction in Male Mice

1 reference

12 December 2020

Excitation-contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes

1 reference

12 December 2020

Animal Experiments in Biomedical Research: A Historical Perspective

1 reference

12 December 2020

Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop.

1 reference

12 December 2020

Revisiting Cardiac Cellular Composition

1 reference

12 December 2020

Cardiac Remodeling: Concepts, Clinical Impact, Pathophysiological Mechanisms and Pharmacologic Treatment.

1 reference

12 December 2020

The electrophysiological development of cardiomyocytes

1 reference

12 December 2020

Post-marketing withdrawal of 462 medicinal products because of adverse drug reactions: a systematic review of the world literature

1 reference

12 December 2020

Recounting Cardiac Cellular Composition

1 reference

12 December 2020

Crosstalk between the heart and peripheral organs in heart failure

1 reference

12 December 2020

Extracellular Matrix and Dermal Fibroblast Function in the Healing Wound

1 reference

12 December 2020

Translational neurocardiology: preclinical models and cardioneural integrative aspects

1 reference

12 December 2020

Models of Heart Failure Based on the Cardiotoxicity of Anticancer Drugs.

1 reference

12 December 2020

Towards 3D in vitro models for the study of cardiovascular tissues and disease

1 reference

12 December 2020

Bioengineered living cardiac and venous valve replacements: current status and future prospects.

1 reference

12 December 2020

IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction

1 reference

12 December 2020

Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons

1 reference

12 December 2020

Biology of the cardiac myocyte in heart disease

1 reference

12 December 2020

hiPSC-derived cardiomyocytes from Brugada Syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalities

1 reference

12 December 2020

Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells.

1 reference

12 December 2020

The novel H2 S donor 4-carboxy-phenyl isothiocyanate inhibits mast cell degranulation and renin release by decreasing intracellular calcium.

1 reference

12 December 2020

A Precision Medicine Approach to the Rescue of Function on Malignant Calmodulinopathic Long-QT Syndrome.

1 reference

12 December 2020

An iPSC-derived vascular model of Marfan syndrome identifies key mediators of smooth muscle cell death

1 reference

12 December 2020

Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction

1 reference

12 December 2020

In vitro models of the cardiac microenvironment to study myocyte and non-myocyte crosstalk: bioinspired approaches beyond the polystyrene dish.

1 reference

12 December 2020

Elucidating arrhythmogenic mechanisms of long-QT syndrome CALM1-F142L mutation in patient-specific induced pluripotent stem cell-derived cardiomyocytes.

1 reference

12 December 2020

Activated T Lymphocytes are Essential Drivers of Pathological Remodeling in Ischemic Heart Failure

1 reference

12 December 2020

Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination.

1 reference

12 December 2020

Disease Modeling in Stem Cell-Derived 3D Organoid Systems.

1 reference

12 December 2020

Macrophages Facilitate Electrical Conduction in the Heart.

1 reference

12 December 2020

Role of Inflammation in Heart Failure

1 reference

12 December 2020

Cardiac fibroblasts: more than mechanical support

1 reference

12 December 2020

Species-Dependent Mechanisms of Cardiac Arrhythmia: A Cellular Focus

1 reference

12 December 2020

Correlation of Ventricular Arrhythmogenesis with Neuronal Remodeling of Cardiac Postganglionic Parasympathetic Neurons in the Late Stage of Heart Failure after Myocardial Infarction

1 reference

12 December 2020

Significance of Ischemic Heart Disease in Patients With Heart Failure and Preserved, Midrange, and Reduced Ejection Fraction: A Nationwide Cohort Study

1 reference

12 December 2020

Dedifferentiation, Proliferation, and Redifferentiation of Adult Mammalian Cardiomyocytes After Ischemic Injury.

1 reference

12 December 2020

Preexisting endothelial cells mediate cardiac neovascularization after injury

1 reference

12 December 2020

Adult Human Primary Cardiomyocyte-Based Model for the Simultaneous Prediction of Drug-Induced Inotropic and Pro-arrhythmia Risk

1 reference

12 December 2020

Probing the Electrophysiology of the Developing Heart.

1 reference

12 December 2020

Disease Modeling Using 3D Organoids Derived from Human Induced Pluripotent Stem Cells.

1 reference

12 December 2020

Advanced maturation of human cardiac tissue grown from pluripotent stem cells.

1 reference

12 December 2020

Induction of Pluripotent Stem Cell-Derived Cardiomyocyte Toxicity by Supernatant of Long Term-Stored Red Blood Cells in Vitro

1 reference

12 December 2020

Cardiac Remodeling: Endothelial Cells Have More to Say Than Just NO.

1 reference

12 December 2020

Electrophysiologic Characterization of Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Atrial Cardiomyocytes.

1 reference

12 December 2020

Human Cardiac Fibroblasts Engage the Sarcoplasmic Reticulum in Induced Pluripotent Stem Cell-Derived Cardiomyocyte Excitation-Contraction Coupling

1 reference

12 December 2020

Cardiomyocyte-Endothelial Cell Interactions in Cardiac Remodeling and Regeneration

1 reference

12 December 2020

The interstitium in cardiac repair: role of the immune-stromal cell interplay

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS19113361

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30373227%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

PubMed publication ID

30373227

1 reference