(Q58164852)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684486%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

title

Silencing the MET oncogene leads to regression of experimental tumors and metastases (English)

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3 January 2020

1

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3 January 2020

Paolo M. Comoglio

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684486%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Silvia Giordano

6

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3 January 2020

author name string

Migliore C

2

1 reference

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3 January 2020

Ghiso E

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684486%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

De Rosa G

4

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3 January 2020

language of work or name

English

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publication date

6 August 2007

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3 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684486%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684486%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

page(s)

684-693

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3 January 2020

issue

5

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210697

3 January 2020

exact match

0 references

cites work

Concomitant activation of pathways downstream of Grb2 and PI 3-kinase is required for MET-mediated metastasis.

1 reference

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Met, metastasis, motility and more

21 January 2018

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The MET oncogene drives a genetic programme linking cancer to haemostasis

21 January 2018

1 reference

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Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

21 January 2018

1 reference

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Dissemination and growth of cancer cells in metastatic sites

21 January 2018

1 reference

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Essential role for oncogenic Ras in tumour maintenance

21 January 2018

1 reference

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Series Introduction: Invasive growth: from development to metastasis

21 January 2018

1 reference

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Latest developments and in vivo use of the Tet system: ex vivo and in vivo delivery of tetracycline-regulated genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Cancer therapy: can the challenge be MET?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

21 January 2018

1 reference

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Reversible tumorigenesis by MYC in hematopoietic lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

21 January 2018

1 reference

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Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

HGF/SF-Met signaling in tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

The semaphorin 4D receptor controls invasive growth by coupling with Met

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Hepatocyte growth factor induces cell scattering through MAPK/Egr-1-mediated upregulation of Snail

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Cancer metastasis: building a framework

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Reversibility of acute B-cell leukaemia induced by BCR-ABL1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

The Sema domain of Met is necessary for receptor dimerization and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

A novel germ line juxtamembrane Met mutation in human gastric cancer

21 January 2018

1 reference

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Genetic instabilities in human cancers

21 January 2018

1 reference

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Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition

21 January 2018

1 reference

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Targeting the tumor and its microenvironment by a dual-function decoy Met receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

The clonal evolution of tumor cell populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

MET overexpression turns human primary osteoblasts into osteosarcomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Ab-induced ectodomain shedding mediates hepatocyte growth factor receptor down-regulation and hampers biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

21 January 2018

1 reference

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Hypoxia signalling in cancer and approaches to enforce tumour regression

21 January 2018

1 reference

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C-terminal truncated forms of Met, the hepatocyte growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Karyotypic analysis of gastric carcinoma cell lines carrying an amplified c-met oncogene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation

21 January 2018

1 reference

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Making tubes: step by step

21 January 2018

1 reference

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Novel mutations of the MET proto-oncogene in papillary renal carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

The role of hepatocyte growth factor and its receptor c-met in interactions between lymphocytes and stromal cells in secondary human lymphoid organs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

21 January 2018

1 reference

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Validation of met as a therapeutic target in alveolar and embryonal rhabdomyosarcoma.

21 January 2018

1 reference

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Epithelial-mesenchymal transitions in development and pathologies

21 January 2018

1 reference

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Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Scatter-factor and semaphorin receptors: cell signalling for invasive growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

TGFalpha expression impairs Trastuzumab-induced HER2 downregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

HGF/SF-met signaling in the control of branching morphogenesis and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

Invasive growth: from development to metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

7 January 2021

Dysregulation of Met receptor tyrosine kinase activity in invasive tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

7 January 2021

Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

7 January 2021

Hepatocyte growth factor is a regulator of monocyte-macrophage function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

7 January 2021

RNAi technology and lentiviral delivery as a powerful tool to suppress Tpr-Met-mediated tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210697

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1210697

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17684486%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference