(Q58166105)

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26 February 2020

title

Probing the conformational diversity of cancer-associated mutations in p53 with ion-mobility mass spectrometry (English)

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26 February 2020

2

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26 February 2020

David J Clarke

4

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26 February 2020

Mike Morris

6

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26 February 2020

Perdita Barran

8

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26 February 2020

author name string

Ewa Jurneczko

1

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26 February 2020

Massimiliano Porrini

3

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26 February 2020

Iain D G Campuzano

5

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26 February 2020

Penka V Nikolova

7

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26 February 2020

language of work or name

English

0 references

publication date

14 March 2013

1 reference

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Angewandte Chemie International Edition

26 February 2020

published in

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26 February 2020

volume

52

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26 February 2020

page(s)

4370-4374

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26 February 2020

issue

16

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Structural biology of the tumor suppressor p53.

26 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Structural biology of the tumor suppressor p53 and cancer-associated mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Thermodynamic stability of wild-type and mutant p53 core domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Mechanism of rescue of common p53 cancer mutations by second-site suppressor mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Effects of common cancer mutations on stability and DNA binding of full-length p53 compared with isolated core domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

In the quest for stable rescuing mutants of p53: computational mutagenesis of flexible loop L1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

p53-Induced DNA bending: the interplay between p53-DNA and p53-p53 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

How useful is ion mobility mass spectrometry for structural biology? The relationship between protein crystal structures and their collision cross sections in the gas phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Ion mobility mass spectrometry of proteins and protein assemblies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Biomolecule analysis by ion mobility spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Intrinsic disorder in proteins: a challenge for (un)structural biology met by ion mobility-mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Collision cross sections of proteins and their complexes: a calibration framework and database for gas-phase structural biology

21 January 2018

1 reference

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Development of an ion mobility quadrupole time of flight mass spectrometer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Structure of the human p53 core domain in the absence of DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Hot-spot mutants of p53 core domain evince characteristic local structural changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Structural basis of DNA recognition by p53 tetramers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

p53 tagged sites from human genomic DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Identification of p53 as a sequence-specific DNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

Four p53 DNA-binding domain peptides bind natural p53-response elements and bend the DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201210015

21 January 2018

Identifiers

DOI

10.1002/ANIE.201210015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23494921%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference