(Q58450503)

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Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22031092%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Growth-hormone-induced signal transducer and activator of transcription 5 signaling causes gigantism, inflammation, and premature death but protects mice from aggressive liver cancer (English)

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15 January 2020

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Jan-Wilhelm Kornfeld

5

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15 January 2020

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15 January 2020

Kenneth Snibson

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15 January 2020

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15 January 2020

Richard Moriggl

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15 January 2020

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Katrin Friedbichler

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15 January 2020

Madeleine Themanns

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15 January 2020

Michaela Schlederer

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15 January 2020

Susanne Haindl

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15 January 2020

Thomas Kolbe

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15 January 2020

Mathias Mueller

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15 January 2020

Kristina M Mueller

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15 January 2020

Luigi M Terracciano

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15 January 2020

Andrey V Kozlov

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15 January 2020

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13 January 2012

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15 January 2020

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15 January 2020

55

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15 January 2020

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15 January 2020

941-952

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15 January 2020

Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Recent advances in growth hormone signaling

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Genomic dissection of the cytokine-controlled STAT5 signaling network in liver

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Diagnosis and therapy of nonalcoholic steatohepatitis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Signal transducers and activators of transcription 5b activation enhances hepatocellular carcinoma aggressiveness through induction of epithelial-mesenchymal transition.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Hepatocellular carcinoma in cirrhosis: incidence and risk factors

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Consequences of growth hormone (GH) overexpression and GH resistance

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

New murine model for hepatocellular carcinoma: transgenic mice expressing metallothionein-ovine growth hormone fusion gene

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Comparison of intrahepatic lymphocytes from normal and growth hormone transgenic mice with chronic hepatitis and liver cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Risk of cancer in patients treated with human pituitary growth hormone in the UK, 1959-85: a cohort study

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Role of the growth hormone–IGF-1 axis in cancer

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

The IGF axis and hepatocarcinogenesis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Accelerated growth and visceral lesions in transgenic mice expressing foreign genes of the growth hormone family: an overview

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

IL-10 and TGF-beta redundantly protect against severe liver injury and mortality during acute schistosomiasis

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Growth allometry of the organs in giant transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Impairment of hepatic growth hormone and glucocorticoid receptor signaling causes steatosis and hepatocellular carcinoma in mice.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

GH-dependent STAT5 signaling plays an important role in hepatic lipid metabolism

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Signal integration by JNK and p38 MAPK pathways in cancer development

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

p38gamma MAPK cooperates with c-Jun in trans-activating matrix metalloproteinase 9.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Hepatocyte IKKbeta/NF-kappaB inhibits tumor promotion and progression by preventing oxidative stress-driven STAT3 activation

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B negatively regulate cell proliferation through the activation of cyclin-dependent kinase inhibitor 2b (Cdkn2b) and Cdkn1a expression

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Role of Stat3 in regulating p53 expression and function

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

21 January 2018

Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

7 January 2021

based on heuristic

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Loss of signal transducer and activator of transcription 5 leads to hepatosteatosis and impaired liver regeneration

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

7 January 2021

based on heuristic

inferred from DOI database lookup

Growth hormone-stimulated IGF-1 generation in cirrhosis reflects hepatocellular dysfunction

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

7 January 2021

based on heuristic

inferred from DOI database lookup

High, persistent hepatocellular proliferation and apoptosis precede hepatocarcinogenesis in growth hormone transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

7 January 2021

based on heuristic

inferred from DOI database lookup

Hepatic regeneration. The role of regeneration in pathogenesis of chronic liver diseases.

1 reference

https://api.crossref.org/works/10.1002%2FHEP.24765

7 January 2021

based on heuristic

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Identifiers

10.1002/HEP.24765

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22031092%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22031092%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

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