(Q58665602)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17091495%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Distinct roles of protein kinase R and toll-like receptor 3 in the activation of astrocytes by viral stimuli (English)

1 reference

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21 December 2019

0 references

0 references

2

1 reference

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21 December 2019

author name string

Pamela A Carpentier

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17091495%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Stephen D Miller

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17091495%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

publication date

1 February 2007

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21 December 2019

1 reference

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21 December 2019

volume

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17091495%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

239-252

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21 December 2019

issue

3

1 reference

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Innate and adaptive immune responses of the central nervous system

21 December 2019

cites work

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Broad expression of Toll-like receptors in the human central nervous system

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Infectious causes of multiple sclerosis

21 January 2018

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Epidemiologic evidence for multiple sclerosis as an infection

21 January 2018

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An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy

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Toll-like receptor 3: a link between toll-like receptor, interferon and viruses

21 January 2018

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Subcellular localization of Toll-like receptor 3 in human dendritic cells

21 January 2018

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Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

21 January 2018

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Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

21 January 2018

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

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7 January 2021

Role of protein kinase R in double-stranded RNA-induced expression of nitric oxide synthase in human astroglia

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7 January 2021

Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

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7 January 2021

CCR5(+) and CXCR3(+) T cells are increased in multiple sclerosis and their ligands MIP-1alpha and IP-10 are expressed in demyelinating brain lesions

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7 January 2021

In utero infection and adult schizophrenia

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7 January 2021

Differential activation of astrocytes by innate and adaptive immune stimuli

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7 January 2021

Immunohistochemical localization of phosphorylated protein kinase R and phosphorylated eukaryotic initiation factor-2 alpha in the central nervous system of SJL mice with experimental allergic encephalomyelitis.

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7 January 2021

Demyelinating lesions due to Theiler's virus are associated with ongoing central nervous system infection

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7 January 2021

Phosphorylation of eukaryotic initiation factor-2alpha (eIF2alpha) is associated with neuronal degeneration in Alzheimer's disease.

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7 January 2021

Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.

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7 January 2021

Epitope spreading and molecular mimicry as triggers of autoimmunity in the Theiler's virus-induced demyelinating disease model of multiple sclerosis

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7 January 2021

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

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7 January 2021

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

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7 January 2021

Preferential expression and function of Toll-like receptor 3 in human astrocytes

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7 January 2021

Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors

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7 January 2021

Immune responses to RNA-virus infections of the CNS.

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7 January 2021

Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus

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7 January 2021

Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus

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7 January 2021

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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7 January 2021

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways.

1 reference

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7 January 2021

2-Aminopurine inhibits the double-stranded RNA-dependent protein kinase both in vitro and in vivo

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7 January 2021

Interferon gene regulation: not all roads lead to Tolls

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7 January 2021

Characterization of double-stranded-RNA-activated kinase that phosphorylates alpha subunit of eukaryotic initiation factor 2 (eIF-2 alpha) in reticulocyte lysates

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7 January 2021

IL-6 detection in multiple sclerosis brain.

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7 January 2021

Activation of the mammalian immune system by siRNAs.

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7 January 2021

Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.

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7 January 2021

Herpes simplex virus selectively induces expression of the CC chemokine RANTES/CCL5 in macrophages through a mechanism dependent on PKR and ICP0

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7 January 2021

Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading

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7 January 2021

The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis

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7 January 2021

Low TRBP levels support an innate human immunodeficiency virus type 1 resistance in astrocytes by enhancing the PKR antiviral response

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7 January 2021

Induction of selected chemokines in glial cells infected with Theiler's virus

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7 January 2021

The scope and activation mechanisms of chemokine gene expression in primary astrocytes following infection with Theiler's virus

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7 January 2021

Infection with Theiler's murine encephalomyelitis virus directly induces proinflammatory cytokines in primary astrocytes via NF-kappaB activation: potential role for the initiation of demyelinating disease

1 reference

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7 January 2021

TLR3-mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: differential signaling mechanisms of TLR3-induced IP-10 and IL-8 gene expression.

1 reference

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7 January 2021

Activation of the cell stress kinase PKR in Alzheimer's disease and human amyloid precursor protein transgenic mice

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7 January 2021

Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue

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7 January 2021

Antiviral actions of interferons

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7 January 2021

Haptoglobin polymorphism, iron metabolism and mortality in HIV infection.

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7 January 2021

Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7

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7 January 2021

Distinct and essential roles of transcription factors IRF-3 and IRF-7 in response to viruses for IFN-alpha/beta gene induction

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7 January 2021

Involvement of the IRF family transcription factor IRF-3 in virus-induced activation of the IFN-beta gene

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7 January 2021

TLR3 in antiviral immunity: key player or bystander?

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7 January 2021

Double-stranded RNA signals antiviral and inflammatory programs and dysfunctional glutamate transport in TLR3-expressing astrocytes

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7 January 2021

Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions.

1 reference

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7 January 2021

Induction of chemokine and cytokine genes in astrocytes following infection with Theiler's murine encephalomyelitis virus is mediated by the Toll-like receptor 3.

1 reference

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7 January 2021

Activation of astrocytes in the spinal cord of mice chronically infected with a neurotropic coronavirus

1 reference

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7 January 2021

Enhanced detection of Theiler's virus RNA copy equivalents in the mouse central nervous system by real-time RT-PCR.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20450

7 January 2021

Epitope spreading in immune-mediated diseases: implications for immunotherapy

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20450

7 January 2021

Cytokines and chemokines as mediators of protection and injury in the central nervous system assessed in transgenic mice.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20450

7 January 2021

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20450

7 January 2021

Host and virus determinants of picornavirus pathogenesis and tropism

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20450

7 January 2021

PKR; a sentinel kinase for cellular stress

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20450

7 January 2021

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20450

7 January 2021

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20450

7 January 2021

NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20450

7 January 2021

Astrocytes, not microglia, are the main cells responsible for viral persistence in Theiler's murine encephalomyelitis virus infection leading to demyelination

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20450

7 January 2021

Identifiers

DOI

10.1002/GLIA.20450

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17091495%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference