(Q58721729)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

title

ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

Zinc finger CCHC-type containing 3

19 April 2020

main subject

general chemistry

0 references

1 reference

GOA release 2020-03-11

detection of virus

1 reference

Zinc finger, CCHC domain containing 3

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Jin Wei

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Shu Hongbing

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

author name string

Huan Lian

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Ru Zang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Wen Ye

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Qing Yang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Xia-Nan Zhang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Yun-Da Chen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Yu-Zhi Fu

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Ming-Ming Hu

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Cao-Qi Lei

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Wei-Wei Luo

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Shu Li

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

language of work or name

English

0 references

publication date

22 August 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

page(s)

3349

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/s41467-018-05559-w

19 April 2020

exact match

0 references

cites work

SNX8 mediates IFNγ-triggered noncanonical signaling pathway and host defense against Listeria monocytogenes.

1 reference

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cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders

30 November 2018

1 reference

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Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Human Cytomegalovirus Tegument Protein UL82 Inhibits STING-Mediated Signaling to Evade Antiviral Immunity

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Cyclic GMP-AMP Synthase Is an Innate Immune DNA Sensor for Mycobacterium tuberculosis

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Mitochondrial DNA stress primes the antiviral innate immune response

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Improved vectors and genome-wide libraries for CRISPR screening

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Post-transcriptional regulation of gene expression in innate immunity.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Genome-scale CRISPR-Cas9 knockout screening in human cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

The capsids of HIV-1 and HIV-2 determine immune detection of the viral cDNA by the innate sensor cGAS in dendritic cells.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Adenovirus detection by the cGAS/STING/TBK1 DNA sensing cascade

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Structural mechanism of cytosolic DNA sensing by cGAS

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

30 November 2018

Immune sensing of DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

STING recognition of cytoplasmic DNA instigates cellular defense

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

The STING in the tail for cytosolic DNA-dependent activation of IRF3.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

STING-dependent signaling.

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

IFI16 is an innate immune sensor for intracellular DNA

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Recognition of microorganisms and activation of the immune response

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Convergence of the NF-kappaB and IRF pathways in the regulation of the innate antiviral response

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Pathogen recognition and innate immunity

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

VISA is an adapter protein required for virus-triggered IFN-beta signaling

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6105683

10.1038/S41467-018-05559-W

30 November 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30135424%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

1 reference