(Q59446927)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29720723%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

2 references

1 December 2020

6 December 2020

Pro-tumorigenic roles of fibroblast activation protein in cancer: back to the basics (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29720723%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

0 references

1 reference

3 April 2019

1 reference

28 September 2019

1 reference

12 October 2019

1 reference

15 December 2019

1 reference

1 December 2020

1 reference

6 December 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29720723%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

author name string

Ellen Puré

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29720723%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

language of work or name

English

0 references

publication date

3 May 2018

1 reference

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25 March 2020

1 August 2018

2 references

1 December 2020

6 December 2020

9 references

3 April 2019

30 June 2019

28 September 2019

12 October 2019

15 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29720723%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

18 September 2020

1 December 2020

6 December 2020

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29720723%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

issue

32

1 reference

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25 March 2020

page(s)

4343-4357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29720723%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/s41388-018-0275-3

25 March 2020

exact match

0 references

cites work

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Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes

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7 January 2021

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Characterization of dedifferentiating human mature adipocytes from the visceral and subcutaneous fat compartments: fibroblast-activation protein alpha and dipeptidyl peptidase 4 as major components of matrix remodeling

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Downregulation of FAP suppresses cell proliferation and metastasis through PTEN/PI3K/AKT and Ras-ERK signaling in oral squamous cell carcinoma

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7 January 2021

Stromal Expression of Fibroblast Activation Protein Alpha (FAP) Predicts Platinum Resistance and Shorter Recurrence in patients with Epithelial Ovarian Cancer

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7 January 2021

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7 January 2021

The prognostic significance of cancer-associated fibroblasts in esophageal squamous cell carcinoma

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7 January 2021

Evaluation of a 5-Marker Blood Test for Colorectal Cancer Early Detection in a Colorectal Cancer Screening Setting.

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7 January 2021

Scaffold-Free Coculture Spheroids of Human Colonic Adenocarcinoma Cells and Normal Colonic Fibroblasts Promote Tumorigenicity in Nude Mice.

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7 January 2021

Fibroblast activation protein protects bortezomib-induced apoptosis in multiple myeloma cells through β-catenin signaling pathway

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7 January 2021

MM-BMSCs induce naïve CD4+ T lymphocytes dysfunction through fibroblast activation protein α

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7 January 2021

Reversal of liver cancer-associated stellate cell-induced stem-like characteristics in SMMC-7721 cells by 8-bromo-7-methoxychrysin via inhibiting STAT3 activation

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7 January 2021

Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation

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7 January 2021

Activation of the A2B adenosine receptor in B16 melanomas induces CXCL12 expression in FAP-positive tumor stromal cells, enhancing tumor progression

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7 January 2021

Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer

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7 January 2021

Estrogen-mediated activation of fibroblasts and its effects on the fibroid cell proliferation

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7 January 2021

GPR30 Promotes Prostate Stromal Cell Activation via Suppression of ERα Expression and Its Downstream Signaling Pathway.

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7 January 2021

Malignant ascites-derived exosomes promote proliferation and induce carcinoma-associated fibroblasts transition in peritoneal mesothelial cells

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7 January 2021

Human telomerase reverse transcriptase (hTERT) promotes cancer invasion by modulating cathepsin D via early growth response (EGR)-1.

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7 January 2021

Transcriptional regulation of seprase in invasive melanoma cells by transforming growth factor-β signaling

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7 January 2021

Ultrasensitive Fluorescent Probes Reveal an Adverse Action of Dipeptide Peptidase IV and Fibroblast Activation Protein during Proliferation of Cancer Cells.

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7 January 2021

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta

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7 January 2021

Estrogen biology: new insights into GPER function and clinical opportunities

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7 January 2021

Low expression of miR-30a-5p induced the proliferation and invasion of oral cancer via promoting the expression of FAP.

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7 January 2021

Rapid fibroblast activation in mammalian cells induced by silicon nanowire arrays

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7 January 2021

Cell adhesion and spreading behavior on vertically aligned silicon nanowire arrays

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7 January 2021

Regulation of the fate of human mesenchymal stem cells by mechanical and stereo-topographical cues provided by silicon nanowires.

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7 January 2021

Extracellular matrix directs phenotypic heterogeneity of activated fibroblasts

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7 January 2021

A specific, transmembrane interface regulates fibroblast activation protein (FAP) homodimerization, trafficking and exopeptidase activity.

1 reference

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7 January 2021

A rare variant in human fibroblast activation protein associated with ER stress, loss of enzymatic function and loss of cell surface localisation

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7 January 2021

A novel protease-docking function of integrin at invadopodia

1 reference

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7 January 2021

The stromal cell-surface protease fibroblast activation protein-α localizes to lipid rafts and is recruited to invadopodia.

1 reference

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7 January 2021

Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α

1 reference

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7 January 2021

Neuropeptide Y is a physiological substrate of fibroblast activation protein: Enzyme kinetics in blood plasma and expression of Y2R and Y5R in human liver cirrhosis and hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Matrilysin/matrix metalloproteinase-7(MMP7) cleavage of perlecan/HSPG2 creates a molecular switch to alter prostate cancer cell behavior

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Cleavage of Type I Collagen by Fibroblast Activation Protein-α Enhances Class A Scavenger Receptor Mediated Macrophage Adhesion

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Fibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Rush to the fire: FGF21 extinguishes metabolic stress, metaflammation and tissue damage

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Human FGF-21 Is a Substrate of Fibroblast Activation Protein

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Fibroblast Activation Protein Cleaves and Inactivates Fibroblast Growth Factor 21

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Circulating FGF21 proteolytic processing mediated by fibroblast activation protein

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Fibroblast activation protein increases metastatic potential of fibrosarcoma line HT1080 through upregulation of integrin-mediated signaling pathways.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Dataset on FAP-induced emergence of spontaneous metastases and on the preparation of activatable FAP-targeting immunoliposomes to detect the metastases

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Integral membrane protease fibroblast activation protein sensitizes fibrosarcoma to chemotherapy and alters cell death mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Impact of fibroblast activation protein on osteosarcoma cell lines in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

FAP-α (Fibroblast activation protein-α) is involved in the control of human breast cancer cell line growth and motility via the FAK pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Specific inhibition of fibroblast activation protein (FAP)-alpha prevents tumor progression in vitro.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Tumor immunotherapy targeting fibroblast activation protein, a product expressed in tumor-associated fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Effective immunoconjugate therapy in cancer models targeting a serine protease of tumor fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Anti-tumor effects of DNA vaccine targeting human fibroblast activation protein α by producing specific immune responses and altering tumor microenvironment in the 4T1 murine breast cancer model

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Enhancement of fibroblast activation protein α-based vaccines and adenovirus boost immunity by cyclophosphamide through inhibiting IL-10 expression in 4T1 tumor bearing mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Improvement of anti-tumor immunity of fibroblast activation protein α based vaccines by combination with cyclophosphamide in a murine model of breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Cyclophosphamide enhances anti-tumor effects of a fibroblast activation protein α-based DNA vaccine in tumor-bearing mice with murine breast carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Depletion of FAP+ cells reduces immunosuppressive cells and improves metabolism and functions CD8+T cells within tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Curcumin combined with FAPαc vaccine elicits effective antitumor response by targeting indolamine-2,3-dioxygenase and inhibiting EMT induced by TNF-α in melanoma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Immunization of stromal cell targeting fibroblast activation protein providing immunotherapy to breast cancer mouse model.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

A whole-cell tumor vaccine modified to express fibroblast activation protein induces antitumor immunity against both tumor cells and cancer-associated fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Protein Nanocage Mediated Fibroblast-Activation Protein Targeted Photoimmunotherapy To Enhance Cytotoxic T Cell Infiltration and Tumor Control.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

A potent immunotoxin targeting fibroblast activation protein for treatment of breast cancer in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

A multi-antigen vaccine in combination with an immunotoxin targeting tumor-associated fibroblast for treating murine melanoma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Expression of anti-VEGF antibody together with anti-EGFR or anti-FAP enhances tumor regression as a result of vaccinia virotherapy

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

RG7386, a Novel Tetravalent FAP-DR5 Antibody, Effectively Triggers FAP-Dependent, Avidity-Driven DR5 Hyperclustering and Tumor Cell Apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

In vivo near-infrared fluorescence imaging of FAP-expressing tumors with activatable FAP-targeted, single-chain Fv-immunoliposomes

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Bispecific single-chain diabody-immunoliposomes targeting endoglin (CD105) and fibroblast activation protein (FAP) simultaneously

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Potential of activatable FAP-targeting immunoliposomes in intraoperative imaging of spontaneous metastases

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Activatable bispecific liposomes bearing fibroblast activation protein directed single chain fragment/Trastuzumab deliver encapsulated cargo into the nuclei of tumor cells and the tumor microenvironment simultaneously

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Antitumor effects of chimeric receptor engineered human T cells directed to tumor stroma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Tumor-Promoting Desmoplasia Is Disrupted by Depleting FAP-Expressing Stromal Cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Stromal antigen targeting by a humanised monoclonal antibody: an early phase II trial of sibrotuzumab in patients with metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Fibroblast Activation Protein α Activated Tripeptide Bufadienolide Antitumor Prodrug with Reduced Cardiotoxicity

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Pharmacokinetics and toxicology of a fibroblast activation protein (FAP)-activated prodrug in murine xenograft models of human cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Iterative design of emetine-based prodrug targeting fibroblast activation protein (FAP) and dipeptidyl peptidase IV DPPIV using a tandem enzymatic activation strategy.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

A tumor-targeted activatable phthalocyanine-tetrapeptide-doxorubicin conjugate for synergistic chemo-photodynamic therapy.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Transformable Peptide Nanocarriers for Expeditious Drug Release and Effective Cancer Therapy via Cancer-Associated Fibroblast Activation.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Selective Activation of Anticancer Chemotherapy by Cancer-Associated Fibroblasts in the Tumor Microenvironment.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

A synthetic urinary probe-coated nanoparticles sensitive to fibroblast activation protein α for solid tumor diagnosis

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Selective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP).

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Phase II trial of single agent Val-boroPro (Talabostat) inhibiting Fibroblast Activation Protein in patients with metastatic colorectal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Phase II trial of talabostat and docetaxel in advanced non-small cell lung cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Phase II assessment of talabostat and cisplatin in second-line stage IV melanoma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Targeting of cancer‑associated fibroblasts enhances the efficacy of cancer chemotherapy by regulating the tumor microenvironment

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Suppression of tumor growth in mice by rationally designed pseudopeptide inhibitors of fibroblast activation protein and prolyl oligopeptidase

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Inhibitor-Decorated Polymer Conjugates Targeting Fibroblast Activation Protein.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0275-3

7 January 2021

Differential expression of cell surface antigens and glial fibrillary acidic protein in human astrocytoma subsets

1 reference

12 December 2020

A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells

1 reference

12 December 2020

Regulation and heteromeric structure of the fibroblast activation protein in normal and transformed cells of mesenchymal and neuroectodermal origin

1 reference

12 December 2020

Expression of the fibroblast activation protein during mouse embryo development

1 reference

12 December 2020

Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice

1 reference

12 December 2020

Mixed nanomicelles as potential carriers for systemic delivery of Z-GP-Dox, an FAPα-based doxorubicin prodrug: formulation and pharmacokinetic evaluation

1 reference

12 December 2020

Lipopolysaccharide activated TLR4/NF-κB signaling pathway of fibroblasts from uterine fibroids

1 reference

12 December 2020

Promotion of Cellular Growth and Motility Is Independent of Enzymatic Activity of Fibroblast Activation Protein-α.

1 reference

12 December 2020

Condition medium of HepG-2 cells induces the transdifferentiation of human umbilical cord mesenchymal stem cells into cancerous mesenchymal stem cells

1 reference

12 December 2020

10.1038/S41388-018-0275-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29720723%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29720723%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference