(Q60370453)

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Somatic Hypermutation of Ig Genes is Affected Differently by Failures in Apoptosis Caused by Disruption of Fas (lpr Mutation) or by Overexpression of Bcl-2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16764695%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Somatic hypermutation of Ig genes is affected differently by failures in apoptosis caused by disruption of Fas (lpr mutation) or by overexpression of Bcl-2 (English)

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16764695%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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Africa González Fernández

4

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29 January 2020

author name string

Mastache EF

1

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29 January 2020

Lindroth K

2

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29 January 2020

Fernández C

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29 January 2020

publication date

1 June 2006

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29 January 2020

Scandinavian Journal of Immunology

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29 January 2020

63

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29 January 2020

6

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29 January 2020

420-429

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29 January 2020

Apoptosis in the development and maintenance of the immune system

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Maturation of the immune response in germinal centers

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Clonal selection and learning in the antibody system

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Life and death in germinal centers (redux).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Immunological tolerance in germinal centres

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

V(D)J Recombination in Mature B Cells: A Mechanism for Altering Antibody Responses

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Biochemical pathways of caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Apoptotic pathways: paper wraps stone blunts scissors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

CD95's deadly mission in the immune system

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Human germinal center B cells express the apoptosis-inducing genes Fas, c-myc, P53, and Bax but not the survival gene bcl-2

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

The role of clonal selection and somatic mutation in autoimmunity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Bcl-2 obstructs negative selection of autoreactive, hypermutated antibody V regions during memory B cell development.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Relaxed negative selection in germinal centers and impaired affinity maturation in bcl-xL transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Death-receptor contribution to the germinal-center reaction.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Bcl-2 increases memory B cell recruitment but does not perturb selection in germinal centers.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Overexpression of bcl-2 alters usage of mutational hot spots in germinal center B cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Rapid methods for the analysis of immunoglobulin gene hypermutation: application to transgenic and gene targeted mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Novartis Medal Lecture. Antibodies: a paradigm for the evolution of molecular recognition.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Both DNA strands of antibody genes are hypermutation targets

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Elements regulating somatic hypermutation of an immunoglobulin κ gene: Critical role for the intron enhancer/matrix attachment region

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Somatic hypermutation of immunoglobulin genes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Somatic mutation hotspots correlate with DNA polymerase eta error spectrum.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Bcl-2 rescues the germinal center response but does not alter the V gene somatic hypermutation spectrum in MSH2-deficient mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

What role for AID: mutator, or assembler of the immunoglobulin mutasome?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-3083.2006.001758.X

21 January 2018

Identifiers

10.1111/J.1365-3083.2006.001758.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16764695%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16764695%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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