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Screening of antipsychotic drugs in animal models
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scholarly article
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title
Screening of antipsychotic drugs in animal models
(English)
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main subject
drug discovery
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author
Daphna Joel
series ordinal
6
object named as
Daphna Joel
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Ina Weiner
series ordinal
1
object named as
Ina Weiner
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author name string
Inna Gaisler
series ordinal
2
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Daniela Schiller
series ordinal
3
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Amit Green
series ordinal
4
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Lee Zuckerman
series ordinal
5
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publication date
2000
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number of pages
15
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inferred from page(s)
published in
Drug Development Research
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volume
50
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issue
3-4
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page(s)
235-249
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cites work
HPA axis and cytokines dysregulation in schizophrenia: potential implications for the antipsychotic treatment
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21 January 2018
The disorder of consciousness in schizophrenia.
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21 January 2018
Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of D-amphetamine
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21 January 2018
Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence
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21 January 2018
The effects of electrolytic median raphe lesions on two measures of latent inhibition.
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21 January 2018
Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine
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21 January 2018
Differential performance of acute and chronic schizophrenics in a latent inhibition task.
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21 January 2018
Akinesia: a syndrome common to parkinsonism, retarded depression, and negative symptoms of schizophrenia
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21 January 2018
Effect of repeated treatment with desipramine in the behavioral "despair" test in rats: antagonism by "atypical" but not "classical" neuroleptics or antiadrenergic drugs
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21 January 2018
The glycine/NMDA receptor antagonist, L-701,324 reverses isolation-induced deficits in prepulse inhibition in the rat
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21 January 2018
Effects of antidepressants and anticholinergics in a mouse “behavioral despair” test
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21 January 2018
New Insights into the Biology of Schizophrenia through the Mechanism of Action of Clozapine
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21 January 2018
The effects of ritanserin, RU 24969 and 8-OH-DPAT on latent inhibition in the rat.
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21 January 2018
5,7-Dihydroxytryptamine lesions in the fornix-fimbria attenuate latent inhibition.
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21 January 2018
Haloperidol enhancement of latent inhibition: Relation to therapeutic action?
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21 January 2018
Depression in schizophrenia: a comparison of three measures
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21 January 2018
Effects of atypical antipsychotic agents on social behavior in rodents
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21 January 2018
Antipsychotic agents antagonize non-competitive N-methyl-D-aspartate antagonist-induced behaviors
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21 January 2018
Entorhinal but not hippocampal or subicular lesions disrupt latent inhibition in rats.
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21 January 2018
Limbic/mesolimbic connections and the pathogenesis of schizophrenia
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21 January 2018
Amphetamine-produced attenuation of latent inhibition is modulated by stimulus preexposure duration: implications for schizophrenia.
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21 January 2018
Effects of smoking status and schizotypy on latent inhibition
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21 January 2018
Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants
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21 January 2018
Effects of antipsychotics on cognitive behaviour in rats using the delayed non-match to position paradigm.
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21 January 2018
Effects of antipsychotic drugs on latent inhibition: sensitivity and specificity of an animal behavioral model of clinical drug action.
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21 January 2018
Activity of “Seroquel” (ICI 204,636) in Animal Models for Atypical Properties of Antipsychotics: A Comparison with Clozapine
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21 January 2018
The effects of pre- and postweaning rearing conditions on latent inhibition and partial reinforcement extinction effect in male rats.
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21 January 2018
Latent inhibition is unaffected by direct dopamine agonists
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21 January 2018
The latent inhibition model of schizophrenic attention disorder. Haloperidol and sulpiride enhance rats' ability to ignore irrelevant stimuli.
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21 January 2018
From an animal model of an attentional deficit towards new insights into the pathophysiology of schizophrenia
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21 January 2018
Intermittent neuroleptic treatment induces long-lasting abnormal mouthing in the rat.
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21 January 2018
Effects of neuroleptics displaying antidepressant activity on behavior of rats in the forced swimming test
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21 January 2018
PD-135,158, a cholecystokinin(B) antagonist, enhances latent inhibition in the rat.
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21 January 2018
Abolition of latent inhibition by a single 5 mg dose of d-amphetamine in man.
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21 January 2018
Latent inhibition in drug naive schizophrenics: relationship to duration of illness and dopamine D2 binding using SPET.
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21 January 2018
The role of mesolimbic dopaminergic and retrohippocampal afferents to the nucleus accumbens in latent inhibition: implications for schizophrenia
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21 January 2018
Latent inhibition: the nucleus accumbens connection revisited
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21 January 2018
Disruption of latent inhibition in rats with postnatal hippocampal lesions
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21 January 2018
The effects of haloperidol and clozapine on the disruption of sensorimotor gating induced by the noncompetitive glutamate antagonist MK-801.
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21 January 2018
The atypical antipsychotic, remoxipride, blocks phencyclidine-induced disruption of prepulse inhibition in the rat.
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21 January 2018
The positive-negative distinction in drug-free schizophrenic patients. Stability, response to neuroleptics, and prognostic significance
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21 January 2018
Differential effects of intra-accumbens and systemic amphetamine on latent inhibition using an on-baseline, within-subject conditioned suppression paradigm.
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21 January 2018
Amphetamine-induced disruptions of latent inhibition are reinforcer mediated: implications for animal models of schizophrenic attentional dysfunction.
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21 January 2018
Effects of the neuroleptic alpha-flupenthixol on latent inhibition in aversively- and appetitively-motivated paradigms: evidence for dopamine-reinforcer interactions.
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21 January 2018
Drug treatment of the negative symptoms of schizophrenia
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21 January 2018
Mechanisms of action of atypical antipsychotic drugs: a critical analysis
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21 January 2018
Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors.
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21 January 2018
Forebrain monoamines and associative learning: I. Latent inhibition and conditioned inhibition.
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21 January 2018
Latent inhibition in humans: data, theory, and implications for schizophrenia
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21 January 2018
Disorders of attention and perception in early schizophrenia
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21 January 2018
Adult schizophrenia following prenatal exposure to an influenza epidemic
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21 January 2018
Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia
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21 January 2018
The dopamine hypothesis of schizophrenia: a review
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21 January 2018
Reversal of amphetamine-induced behaviours by MDL 100,907, a selective 5-HT2A antagonist.
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21 January 2018
Effects of antidepressants on phencyclidine-induced enhancement of immobility in a forced swimming test in mice.
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21 January 2018
Enhancement of immobility in a forced swimming test by subacute or repeated treatment with phencyclidine: a new model of schizophrenia
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21 January 2018
Information processing and attentional functioning in the developmental course of schizophrenic disorders.
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21 January 2018
Remoxipride, a new potential antipsychotic compound with selective antidopaminergic actions in the rat brain
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21 January 2018
The dopamine D2 antagonist remoxipride acts in vivo on a subpopulation of dopamine D2 receptors.
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21 January 2018
Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test
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21 January 2018
Depression: a new animal model sensitive to antidepressant treatments
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21 January 2018
Acute and long-term effectiveness of clozapine in treatment-resistant psychotic depression
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21 January 2018
Biochemical findings of negative symptoms in schizophrenia and their putative relevance to pharmacologic treatment. A review
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21 January 2018
Amphetamine-induced disruption and haloperidol-induced potentiation of latent inhibition depend on the nature of the stimulus.
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21 January 2018
Relationships among negative, positive, and depressive symptoms in schizophrenia and psychotic depression
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21 January 2018
Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding
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21 January 2018
Clozapine-induced potentiation of latent inhibition is due to its action in the conditioning stage: implications for the mechanism of action of antipsychotic drugs
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21 January 2018
Gender- and age-dependent differences in latent inhibition following pre-weaning non-handling: implications for a neurodevelopmental animal model of schizophrenia.
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21 January 2018
Differential effect of antipsychotics on place navigation of rats in the Morris water maze. A comparative study between novel and reference antipsychotics.
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21 January 2018
The dopamine hypothesis of schizophrenia: focus on the dopamine receptor
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21 January 2018
Disruption of latent inhibition following systemic administration of parachlorophenylalanine (PCPA)
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21 January 2018
Latent inhibition in conditioned emotional response: c-fos immunolabelling evidence for brain areas involved in the rat.
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21 January 2018
Clozapine and haloperidol in an animal model of sensorimotor gating deficits in schizophrenia.
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21 January 2018
Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients
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21 January 2018
Latent inhibition in schizophrenia
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21 January 2018
Both electrolytic and excitotoxic lesions of nucleus accumbens disrupt latent inhibition of learning in rats.
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21 January 2018
Neurobiological substrate of dimensions of schizophrenic illness
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21 January 2018
Mutability and relationship between positive and negative symptoms during neuroleptic treatment in schizophrenia
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21 January 2018
Effects of nicotine and amphetamine on latent inhibition in human subjects
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21 January 2018
A double-blind, controlled comparison of the novel antipsychotic olanzapine versus haloperidol or placebo on anxious and depressive symptoms accompanying schizophrenia.
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21 January 2018
A viral-anatomical explantation of schizophrenia
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21 January 2018
Enhancement of latent inhibition in the rat by the atypical antipsychotic agent remoxipride.
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21 January 2018
Enhancement of latent inhibition in the rat at a high dose of clozapine.
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21 January 2018
Latent inhibition and autonomic responses: a psychophysiological approach
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21 January 2018
Examination of drug-induced and isolation-induced disruptions of prepulse inhibition as models to screen antipsychotic drugs.
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21 January 2018
Antagonism of amphetamine-induced disruption of latent inhibition in rats by haloperidol and ondansetron: implications for a possible antipsychotic action of ondansetron.
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21 January 2018
Implications of normal brain development for the pathogenesis of schizophrenia
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21 January 2018
Cortical maldevelopment, anti-psychotic drugs, and schizophrenia: a search for common ground
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21 January 2018
Neural substrates of latent inhibition: the switching model
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21 January 2018
The switching model of latent inhibition: an update of neural substrates
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21 January 2018
Abolition of the expression but not the acquisition of latent inhibition by chronic amphetamine in rats.
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21 January 2018
The effects of early handling on latent inhibition in male and female rats.
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21 January 2018
Facilitation of the expression but not the acquisition of latent inhibition by haloperidol in rats.
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21 January 2018
Early handling and latent inhibition in the conditioned suppression paradigm.
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21 January 2018
Latent inhibition is not affected by acute or chronic administration of 6 mg/kg dl-amphetamine.
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21 January 2018
Disruption of latent inhibition by acute administration of low doses of amphetamine.
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21 January 2018
A neuroleptic-like effect of ceronapril on latent inhibition
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21 January 2018
The effects of the new antipsychotic, sertindole, on latent inhibition in rats.
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21 January 2018
Differential involvement of the shell and core subterritories of the nucleus accumbens in latent inhibition and amphetamine-induced activity.
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21 January 2018
The latent inhibition model of schizophrenia: further validation using the atypical neuroleptic, clozapine.
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21 January 2018
Haloperidol- and clozapine-induced enhancement of latent inhibition with extended conditioning: implications for the mechanism of action of neuroleptic drugs.
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21 January 2018
Amphetamine-induced disruption of latent inhibition is not reinforcer-mediated.
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21 January 2018
Disrupted and undisruptable latent inhibition following shell and core lesions
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21 January 2018
Effects of four antipsychotics on punished responding in rats
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21 January 2018
Antipsychotic drug effects in a model of schizophrenic attentional disorder: a randomized controlled trial of the effects of haloperidol on latent inhibition in healthy people.
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21 January 2018
Haloperidol enhances latent inhibition in visual tasks in healthy people
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21 January 2018
Reduced latent inhibition in people with schizophrenia: an effect of psychosis or of its treatment.
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21 January 2018
Latent inhibition of conditioned dopamine release in rat nucleus accumbens.
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retrieved
21 January 2018
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DOI
10.1002/1098-2299(200007/08)50:3/4<235::AID-DDR7>3.0.CO;2-R
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