(Q61216219)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

review article

1 reference

title

Putting the 'HAT' back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions (English)

1 reference

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26 January 2020

1

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26 January 2020

author name string

Manuela Basso

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Lata Mahishi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Alan P Kozikowski

4

1 reference

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26 January 2020

Mary E Donohoe

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Brett Langley

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Rajiv R Ratan

7

1 reference

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26 January 2020

language of work or name

English

0 references

publication date

1 May 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Investigational Drugs

26 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

18

1 reference

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26 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

page(s)

573-584

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

26 January 2020

cites work

1 reference

12 December 2020

Neuroprotective effects of gelsolin during murine stroke

1 reference

12 December 2020

CREB-Binding protein acetylates hematopoietic transcription factor GATA-1 at functionally important sites

1 reference

12 December 2020

Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells.

1 reference

12 December 2020

Benefit of valproic acid in suppressing disease progression of ALS model mice

1 reference

12 December 2020

Neuroprotective effects of phenylbutyrate against MPTP neurotoxicity.

1 reference

12 December 2020

Neuroprotection by pharmacologic blockade of the GAPDH death cascade

1 reference

12 December 2020

Maternal care effects on the hippocampal transcriptome and anxiety-mediated behaviors in the offspring that are reversible in adulthood

1 reference

12 December 2020

HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis.

1 reference

12 December 2020

Additive neuroprotective effects of a histone deacetylase inhibitor and a catalytic antioxidant in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

1 reference

12 December 2020

In vitro and ex vivo evaluation of second-generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy

1 reference

12 December 2020

The benzamide M344, a novel histone deacetylase inhibitor, significantly increases SMN2 RNA/protein levels in spinal muscular atrophy cells

1 reference

12 December 2020

Inhibition of histone deacetylation protects wild-type but not gelsolin-deficient neurons from oxygen/glucose deprivation.

1 reference

12 December 2020

Rubinstein-Taybi syndrome: molecular findings and therapeutic approaches to improve cognitive dysfunction

1 reference

12 December 2020

Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia.

1 reference

12 December 2020

Alpha-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity

1 reference

12 December 2020

Pharmacological inhibition of histone deacetylases by suberoylanilide hydroxamic acid specifically alters gene expression and reduces ischemic injury in the mouse brain.

1 reference

12 December 2020

Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes.

1 reference

12 December 2020

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor: effects on gene expression and growth of glioma cells in vitro and in vivo

1 reference

12 December 2020

Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation

1 reference

12 December 2020

CD81, a cell cycle regulator, is a novel target for histone deacetylase inhibition in glioma cells

1 reference

12 December 2020

Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse model

1 reference

12 December 2020

Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation

1 reference

12 December 2020

Repeat-induced epigenetic changes in intron 1 of the frataxin gene and its consequences in Friedreich ataxia

1 reference

12 December 2020

Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells

1 reference

12 December 2020

Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity

1 reference

12 December 2020

Histone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: analysis of the National Brain Databank microarray collection

1 reference

12 December 2020

Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/cip1) in cell cycle-independent neuroprotection

1 reference

12 December 2020

Histone deacetylase inhibitors: possible implications for neurodegenerative disorders

1 reference

12 December 2020

BM88/Cend1 is involved in histone deacetylase inhibition-mediated growth arrest and differentiation of neuroblastoma cells

1 reference

12 December 2020

Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents.

1 reference

12 December 2020

The role of histone acetylation in SMN gene expression.

1 reference

12 December 2020

Sodium phenylbutyrate prolongs survival and regulates expression of anti-apoptotic genes in transgenic amyotrophic lateral sclerosis mice

1 reference

12 December 2020

The power of the dark side: Huntington's disease protein and p53 form a deadly alliance

1 reference

12 December 2020

Chromosomal organization and localization of the novel class IV human histone deacetylase 11 gene

1 reference

12 December 2020

The histone deacetylase inhibitor sodium butyrate protects against cisplatin-induced hearing loss in guinea pigs

1 reference

12 December 2020

Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition

1 reference

12 December 2020

Histone deacetylase inhibition modulates kynurenine pathway activation in yeast, microglia, and mice expressing a mutant huntingtin fragment.

1 reference

12 December 2020

SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome

1 reference

12 December 2020

Brain chromatin remodeling: a novel mechanism of alcoholism.

1 reference

12 December 2020

Histone deacetylase inhibitors: mechanisms and clinical significance in cancer: HDAC inhibitor-induced apoptosis

1 reference

12 December 2020

DNA damage and repair: relevance to mechanisms of neurodegeneration

1 reference

12 December 2020

HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model

1 reference

12 December 2020

Histone deacetylase inhibitors: therapeutic agents and research tools for deciphering motor neuron diseases

1 reference

12 December 2020

A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy

1 reference

12 December 2020

Reduced baseline acetylated histone 3 levels, and a blunted response to HDAC inhibition in lymphocyte cultures from schizophrenia subjects

1 reference

12 December 2020

A preliminary report on spinal muscular atrophy lymphoblastoid cell lines: are they an appropriate tool for drug screening?

1 reference

12 December 2020

Histone deacetylase inhibitors in cancer therapy: new compounds and clinical update of benzamide-type agents

1 reference

12 December 2020

Histone deacetylase inhibitors: mechanisms of cell death and promise in combination cancer therapy

1 reference

12 December 2020

Histone deacetylase inhibitors decrease cocaine but not sucrose self-administration in rats

1 reference

12 December 2020

S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons

1 reference

12 December 2020

Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice

1 reference

12 December 2020

Therapeutic application of histone deacetylase inhibitors for central nervous system disorders

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12 December 2020

The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice

1 reference

12 December 2020

Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons

1 reference

12 December 2020

Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease.

1 reference

12 December 2020

Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity

1 reference

12 December 2020

Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition

1 reference

12 December 2020

Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity.

1 reference

12 December 2020

Synergistic effect of histone hyperacetylation and DNA demethylation in the reactivation of the FMR1 gene.

1 reference

12 December 2020

Regulation of E2F1 activity by acetylation

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12 December 2020

E2F Family Members Are Differentially Regulated by Reversible Acetylation

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12 December 2020

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

1 reference

12 December 2020

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

1 reference

12 December 2020

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

1 reference

12 December 2020

Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics

1 reference

12 December 2020

Selective E2F-dependent gene transcription is controlled by histone deacetylase activity during neuronal apoptosis

1 reference

12 December 2020

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

1 reference

12 December 2020

HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo

1 reference

12 December 2020

Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway

1 reference

12 December 2020

Acetylation of cAMP-responsive element-binding protein (CREB) by CREB-binding protein enhances CREB-dependent transcription

1 reference

12 December 2020

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.

1 reference

12 December 2020

Sp1 and Sp3 Are Oxidative Stress-Inducible, Antideath Transcription Factors in Cortical Neurons

1 reference

12 December 2020

Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101.

1 reference

12 December 2020

Role of Class I and Class II histone deacetylases in carcinoma cells using siRNA

1 reference

12 December 2020

Histone Deacetylase Inhibitors: The Abbott Experience

1 reference

12 December 2020

Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice

1 reference

12 December 2020

Neuronal gelsolin prevents apoptosis by enhancing actin depolymerization

1 reference

12 December 2020

Valproic acid: an old drug newly discovered as inhibitor of histone deacetylases

1 reference

12 December 2020

Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

1 reference

12 December 2020

Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction

1 reference

12 December 2020

Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration.

1 reference

12 December 2020

Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases

1 reference

12 December 2020

Histone deacetylase inhibitors open new doors in cancer therapy

1 reference

12 December 2020

Targeting CREB-binding protein (CBP) loss of function as a therapeutic strategy in neurological disorders

1 reference

12 December 2020

Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons

1 reference

12 December 2020

Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor

1 reference

12 December 2020

Simultaneous and continuous measurement of free concentration of valproate in blood and extracellular space of rat cerebral cortex

1 reference

12 December 2020

Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

1 reference

12 December 2020

The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.

1 reference

12 December 2020

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

1 reference

12 December 2020

The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons.

1 reference

12 December 2020

Neuronal apoptosis induced by histone deacetylase inhibitors.

1 reference

12 December 2020

Regulation of activity of the transcription factor GATA-1 by acetylation

1 reference

12 December 2020

10.1517/13543780902810345

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19388875%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference