(Q61456272)

3

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author name string

Floris J van Dalen

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Marleen H M E van Stevendaal

2

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Martijn Verdoes

Creative Commons Attribution

4

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language of work or name

English

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publication date

20 December 2018

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3 April 2019

25 June 2019

12 October 2019

18 October 2019

8 September 2020

9 September 2020

8 February 2021

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3 April 2019

25 June 2019

12 October 2019

18 October 2019

8 September 2020

9 September 2020

8 February 2021

24

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page(s)

9

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issue

1

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copyright license

7 references

3 April 2019

25 June 2019

12 October 2019

18 October 2019

8 September 2020

9 September 2020

8 February 2021

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on focus list of Wikimedia project

ScienceSource

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cites work

A phase I clinical trial of imiquimod, an oral interferon inducer, administered daily.

1 reference

12 December 2020

Immunotherapeutic uses of CpG oligodeoxynucleotides

1 reference

12 December 2020

Cysteine cathepsins (proteases)--on the main stage of cancer?

1 reference

12 December 2020

Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice.

1 reference

12 December 2020

An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.

1 reference

12 December 2020

A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors

1 reference

12 December 2020

Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

1 reference

12 December 2020

Macrophages promote the invasion of breast carcinoma cells via a colony-stimulating factor-1/epidermal growth factor paracrine loop

1 reference

12 December 2020

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.

1 reference

12 December 2020

Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors.

1 reference

12 December 2020

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis

1 reference

12 December 2020

Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts

1 reference

12 December 2020

Macrophages regulate the angiogenic switch in a mouse model of breast cancer

1 reference

12 December 2020

IL-12 rapidly alters the functional profile of tumor-associated and tumor-infiltrating macrophages in vitro and in vivo

1 reference

12 December 2020

Lipid peroxidation dominates the chemistry of DNA adduct formation in a mouse model of inflammation

1 reference

12 December 2020

Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors

1 reference

12 December 2020

Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft

1 reference

12 December 2020

Oral resiquimod in chronic HCV infection: safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies

1 reference

12 December 2020

Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock

1 reference

12 December 2020

"Re-educating" tumor-associated macrophages by targeting NF-kappaB.

1 reference

12 December 2020

DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

1 reference

12 December 2020

Endocannabinoid 2-arachidonoylglycerol protects neurons by limiting COX-2 elevation

1 reference

12 December 2020

Colony-stimulating factors in inflammation and autoimmunity.

1 reference

12 December 2020

The role of myeloid cells in the promotion of tumour angiogenesis

1 reference

12 December 2020

Exploring the full spectrum of macrophage activation

1 reference

12 December 2020

Macrophages within NSCLC tumour islets are predominantly of a cytotoxic M1 phenotype associated with extended survival.

1 reference

12 December 2020

Extratumoral macrophages promote tumor and vascular growth in an orthotopic rat prostate tumor model

1 reference

12 December 2020

Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages

1 reference

12 December 2020

Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation

1 reference

12 December 2020

Microenvironmental regulation of metastasis

1 reference

12 December 2020

Trophic macrophages in development and disease

1 reference

12 December 2020

The metastatic niche: adapting the foreign soil

1 reference

12 December 2020

M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis

1 reference

12 December 2020

A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth

1 reference

12 December 2020

Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.

1 reference

12 December 2020

A novel copper chelate modulates tumor associated macrophages to promote anti-tumor response of T cells

1 reference

12 December 2020

Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway.

1 reference

12 December 2020

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

1 reference

12 December 2020

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

1 reference

12 December 2020

Macrophage diversity enhances tumor progression and metastasis

1 reference

12 December 2020

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

1 reference

12 December 2020

Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages

1 reference

12 December 2020

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

1 reference

12 December 2020

Antiproliferative and antimetastatic effects of emodin on human pancreatic cancer

1 reference

12 December 2020

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

1 reference

12 December 2020

COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps

1 reference

12 December 2020

Mononuclear phagocyte heterogeneity in cancer: different subsets and activation states reaching out at the tumor site

1 reference

12 December 2020

Tumor-associated macrophages promote angiogenesis and melanoma growth via adrenomedullin in a paracrine and autocrine manner

1 reference

12 December 2020

Reprogramming of TAM toward proimmunogenic type through regulation of MAP kinases using a redox-active copper chelate

1 reference

12 December 2020

Microglial stimulation of glioblastoma invasion involves epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling

1 reference

12 December 2020

Coordinated regulation of myeloid cells by tumours

1 reference

12 December 2020

Differential regulation of the Let-7 family of microRNAs in CD4+ T cells alters IL-10 expression.

1 reference

12 December 2020

Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy

1 reference

12 December 2020

Anti-tumor immune responses of tumor-associated macrophages via toll-like receptor 4 triggered by cationic polymers

1 reference

12 December 2020

Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer.

1 reference

12 December 2020

Sorafenib perpetuates cellular anticancer effector functions by modulating the crosstalk between macrophages and natural killer cells.

1 reference

12 December 2020

Cyclooxygenase-2 inhibition blocks M2 macrophage differentiation and suppresses metastasis in murine breast cancer model

1 reference

12 December 2020

Hydrazinocurcumin Encapsuled nanoparticles "re-educate" tumor-associated macrophages and exhibit anti-tumor effects on breast cancer following STAT3 suppression

1 reference

12 December 2020

Self-assembly of poly-adenine-tailed CpG oligonucleotide-gold nanoparticle nanoconjugates with immunostimulatory activity

1 reference

12 December 2020

Improved quenched fluorescent probe for imaging of cysteine cathepsin activity

1 reference

12 December 2020

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

1 reference

12 December 2020

Euodenine A: A Small-Molecule Agonist of Human TLR4

1 reference

12 December 2020

Phosphatidylserine-targeting antibody induces M1 macrophage polarization and promotes myeloid-derived suppressor cell differentiation

1 reference

12 December 2020

TREM-1 regulates macrophage polarization in ureteral obstruction.

1 reference

12 December 2020

DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclic dinucleotide STING agonist, 2'3'-cGAMP, induces M2 macrophage repolarization

1 reference

12 December 2020

Tumor-associated macrophages: from mechanisms to therapy

1 reference

12 December 2020

Interferon gamma induced by resveratrol analog, HS-1793, reverses the properties of tumor associated macrophages

1 reference

12 December 2020

CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models.

1 reference

12 December 2020

Targeted depletion of tumour-associated macrophages by an alendronate-glucomannan conjugate for cancer immunotherapy

1 reference

12 December 2020

Emodin suppresses pulmonary metastasis of breast cancer accompanied with decreased macrophage recruitment and M2 polarization in the lungs

1 reference

12 December 2020

Molecular mechanisms that influence the macrophage m1-m2 polarization balance

1 reference

12 December 2020

Consistent inhibition of cyclooxygenase drives macrophages towards the inflammatory phenotype

1 reference

12 December 2020

Dopamine induces growth inhibition and vascular normalization through reprogramming M2-polarized macrophages in rat C6 glioma

1 reference

12 December 2020

A phase I clinical trial of bavituximab and paclitaxel in patients with HER2 negative metastatic breast cancer

1 reference

12 December 2020

CD163+ tumor-associated macrophage is a prognostic biomarker and is associated with therapeutic effect on malignant pleural effusion of lung cancer patients

1 reference

12 December 2020

The combination of a novel immunomodulator with a regulatory T cell suppressing antibody (DTA-1) regress advanced stage B16F10 solid tumor by repolarizing tumor associated macrophages in situ

1 reference

12 December 2020

An interferon-γ-delivery system based on chitosan/poly(γ-glutamic acid) polyelectrolyte complexes modulates macrophage-derived stimulation of cancer cell invasion in vitro.

1 reference

12 December 2020

Much More than M1 and M2 Macrophages, There are also CD169(+) and TCR(+) Macrophages

1 reference

12 December 2020

Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides

1 reference

12 December 2020

Tumor necrosis factor-related apoptosis-inducing ligand induces the expression of proinflammatory cytokines in macrophages and re-educates tumor-associated macrophages to an antitumor phenotype

1 reference

12 December 2020

Synergistic antitumor responses by combined GITR activation and sunitinib in metastatic renal cell carcinoma.

1 reference

12 December 2020

High and low molecular weight hyaluronic acid differentially influence macrophage activation

1 reference

12 December 2020

Zoledronic acid prevents the tumor-promoting effects of mesenchymal stem cells via MCP-1 dependent recruitment of macrophages

1 reference

12 December 2020

Dectin-1 Activation by a Natural Product β-Glucan Converts Immunosuppressive Macrophages into an M1-like Phenotype

1 reference

12 December 2020

Autophagy-induced RelB/p52 activation mediates tumour-associated macrophage repolarisation and suppression of hepatocellular carcinoma by natural compound baicalin

1 reference

12 December 2020

Metformin prevents cancer metastasis by inhibiting M2-like polarization of tumor associated macrophages

1 reference

12 December 2020

CDDO-Me inhibits tumor growth and prevents recurrence of pancreatic ductal adenocarcinoma

1 reference

12 December 2020

Modulation of Innate Immune Responses via Covalently Linked TLR Agonists

1 reference

12 December 2020

Bioconjugated Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia

1 reference

12 December 2020

The MSHA strain of Pseudomonas aeruginosa (PA-MSHA) inhibits gastric carcinoma progression by inducing M1 macrophage polarization

1 reference

12 December 2020

Bruton Tyrosine Kinase-Dependent Immune Cell Cross-talk Drives Pancreas Cancer.

1 reference

12 December 2020

Antibody-Mediated Blockade of Phosphatidylserine Enhances the Antitumor Effect of Sorafenib in Hepatocellular Carcinomas Xenografts

1 reference

12 December 2020

Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer

1 reference

12 December 2020

CDDO-Me Redirects Activation of Breast Tumor Associated Macrophages

1 reference

12 December 2020

Targeted delivery of let-7b to reprogramme tumor-associated macrophages and tumor infiltrating dendritic cells for tumor rejection.

1 reference

12 December 2020

Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival

1 reference

12 December 2020

Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis

1 reference

12 December 2020

Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts

1 reference

12 December 2020

Manipulating the NF-κB pathway in macrophages using mannosylated, siRNA-delivering nanoparticles can induce immunostimulatory and tumor cytotoxic functions

1 reference

12 December 2020

PA-MSHA in combination with EGFR tyrosine kinase inhibitor: A new strategy to overcome the drug resistance of non-small cell lung cancer cells

1 reference

12 December 2020

Pancreatic Cancer Cell Exosome-Mediated Macrophage Reprogramming and the Role of MicroRNAs 155 and 125b2 Transfection using Nanoparticle Delivery Systems

1 reference

12 December 2020

Motolimod effectively drives immune activation in advanced cancer patients

1 reference

12 December 2020

Evaluation of the potential therapeutic benefits of macrophage reprogramming in multiple myeloma.

1 reference

12 December 2020

STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation

1 reference

12 December 2020

Polymeric nanoparticles promote macrophage reversal from M2 to M1 phenotypes in the tumor microenvironment.

1 reference

12 December 2020

Phase Ib Trial of the Toll-like Receptor 8 Agonist, Motolimod (VTX-2337), Combined with Cetuximab in Patients with Recurrent or Metastatic SCCHN.

1 reference

12 December 2020

Molecular Pathways: Deciphering Mechanisms of Resistance to Macrophage-Targeted Therapies

1 reference

12 December 2020

Chloroquine (CQ) exerts anti-breast cancer through modulating microenvironment and inducing apoptosis

1 reference

12 December 2020

A facile route to form self-carried redox-responsive vorinostat nanodrug for effective solid tumor therapy

1 reference

12 December 2020

Chlorogenic acid inhibits glioblastoma growth through repolarizating macrophage from M2 to M1 phenotype

1 reference

12 December 2020

Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling

1 reference

12 December 2020

Yeast-mediated mRNA delivery polarizes immuno-suppressive macrophages towards an immuno-stimulatory phenotype

1 reference

12 December 2020

A phase 2, randomized, double-blind, placebo- controlled study of chemo-immunotherapy combination using motolimod with pegylated liposomal doxorubicin in recurrent or persistent ovarian cancer: a Gynecologic Oncology Group partners study.

1 reference

12 December 2020

Discovery of Small Molecules as Multi-Toll-like Receptor Agonists with Proinflammatory and Anticancer Activities.

1 reference

12 December 2020

Colony-Stimulating Factor 1 Receptor Blockade Inhibits Tumor Growth by Altering the Polarization of Tumor-Associated Macrophages in Hepatocellular Carcinoma.

1 reference

12 December 2020

HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model.

1 reference

12 December 2020

Synthetic Toll-Like Receptor 4 (TLR4) and TLR7 Ligands Work Additively via MyD88 To Induce Protective Antiviral Immunity in Mice

1 reference

12 December 2020

Inhibition of colony stimulating factor-1 receptor abrogates microenvironment-mediated therapeutic resistance in gliomas.

1 reference

12 December 2020

Reprogramming of Tumor-Associated Macrophages with Anticancer Therapies: Radiotherapy versus Chemo- and Immunotherapies

1 reference

12 December 2020

PA-MSHA induces apoptosis and suppresses metastasis by tumor associated macrophages in bladder cancer cells

1 reference

12 December 2020

Regulation of Human Macrophage M1-M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1.

1 reference

12 December 2020

Reprogramming Tumor-Associated Macrophages To Reverse EGFRT790M Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat.

1 reference

12 December 2020

TLR Agonist Conjugation: A Chemical Perspective.

1 reference

12 December 2020

Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.

1 reference

12 December 2020

UC-1V150, a potent TLR7 agonist capable of activating macrophages and potentiating mAb-mediated target cell deletion.

1 reference

12 December 2020

Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b

1 reference

12 December 2020

Combined HDAC and Bromodomain Protein Inhibition Reprograms Tumor Cell Metabolism and Elicits Synthetic Lethality in Glioblastoma

1 reference

12 December 2020

Randomized phase III study of docetaxel plus bavituximab in previously treated advanced non-squamous non-small-cell lung cancer

1 reference

12 December 2020

Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory Infiltration

1 reference

12 December 2020

Efficacy of gefitinib‑celecoxib combination therapy in docetaxel‑resistant prostate cancer

1 reference

12 December 2020

TLR-3 Stimulation Skews M2 Macrophages to M1 Through IFN-αβ Signaling and Restricts Tumor Progression

1 reference

12 December 2020

Prior exposure of pancreatic tumors to [sorafenib + vorinostat] enhances the efficacy of an anti-PD-1 antibody

1 reference

12 December 2020

Tumor hypoxia directed multimodal nanotherapy for overcoming drug resistance in renal cell carcinoma and reprogramming macrophages

1 reference

12 December 2020

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

1 reference

12 December 2020

Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity

1 reference

12 December 2020