(Q61813975)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658474%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

title

Adhesion Deregulation in Acute Myeloid Leukaemia (English)

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19 April 2020

1 reference

1

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19 April 2020

Myriam Alcalay

series ordinal

4

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19 April 2020

author name string

Debora Valli

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658474%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Cecilia Restelli

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658474%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

language of work or name

English

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publication date

17 January 2019

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19 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658474%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

volume

8

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19 April 2020

issue

1

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Creative Commons Attribution 4.0 International

19 April 2020

page(s)

66

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copyright license

start time

17 January 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Adhesion molecules on CD34+ hematopoietic cells in normal human bone marrow and leukemia

1 reference

12 December 2020

Hematopoietic progenitor cell expression of the H-CAM (CD44) homing-associated adhesion molecule

1 reference

12 December 2020

Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans

1 reference

12 December 2020

Differential expression of adhesion molecules in acute leukemia

1 reference

12 December 2020

Expression of adhesion molecules on acute leukemic blast cells and sensitivity to normal LAK activity.

1 reference

12 December 2020

Adhesion molecules in haemopoiesis

1 reference

12 December 2020

Connexin43 gap junctions in normal, regenerating, and cultured mouse bone marrow and in human leukemias: their possible involvement in blood formation

1 reference

12 December 2020

The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1.

1 reference

12 December 2020

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1 reference

12 December 2020

Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells

1 reference

12 December 2020

VLA-5 is expressed by mouse and human long-term repopulating hematopoietic cells and mediates adhesion to extracellular matrix protein fibronectin

1 reference

12 December 2020

Inhibition of beta-catenin-mediated transactivation by cadherin derivatives

1 reference

12 December 2020

Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4

1 reference

12 December 2020

Expression of the cell adhesion molecule E-cadherin by the human bone marrow stromal cells and its probable role in CD34(+) stem cell adhesion

1 reference

12 December 2020

Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

1 reference

12 December 2020

Hypermethylation of E-cadherin in leukemia

1 reference

12 December 2020

The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.

1 reference

12 December 2020

A distinct glycoform of CD44 is an L-selectin ligand on human hematopoietic cells

1 reference

12 December 2020

Increased cellular hypoxia and reduced proliferation of both normal and leukaemic cells during progression of acute myeloid leukaemia in rats.

1 reference

12 December 2020

N-cadherin is developmentally regulated and functionally involved in early hematopoietic cell differentiation

1 reference

12 December 2020

Signal transduction by cell adhesion receptors and the cytoskeleton: functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members

1 reference

12 December 2020

Mechanisms associated with cell adhesion mediated drug resistance (CAM-DR) in hematopoietic malignancies

1 reference

12 December 2020

AlphaIIb integrin expression during development of the murine hemopoietic system

1 reference

12 December 2020

Integrins: bidirectional, allosteric signaling machines

1 reference

12 December 2020

Interaction between leukemic-cell VLA-4 and stromal fibronectin is a decisive factor for minimal residual disease of acute myelogenous leukemia

1 reference

12 December 2020

CXCR4 chemokine receptors (CD184) and alpha4beta1 integrins mediate spontaneous migration of human CD34+ progenitors and acute myeloid leukaemia cells beneath marrow stromal cells (pseudoemperipolesis).

1 reference

12 December 2020

Identification of the haematopoietic stem cell niche and control of the niche size

1 reference

12 December 2020

Membrane proteins with immunoglobulin-like domains--a master superfamily of interaction molecules

1 reference

12 December 2020

Relation between CXCR-4 expression, Flt3 mutations, and unfavorable prognosis of adult acute myeloid leukemia

1 reference

12 December 2020

Expression of focal adhesion kinase in acute myeloid leukemia is associated with enhanced blast migration, increased cellularity, and poor prognosis

1 reference

12 December 2020

Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates

1 reference

12 December 2020

Integrin-linked kinase: a cancer therapeutic target unique among its ILK.

1 reference

12 December 2020

In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment

1 reference

12 December 2020

CXCR4 is a prognostic marker in acute myelogenous leukemia.

1 reference

12 December 2020

Juvenile syndecan-1 null mice are protected from carcinogen-induced tumor development.

1 reference

12 December 2020

Functional CXCR4-expressing microparticles and SDF-1 correlate with circulating acute myelogenous leukemia cells

1 reference

12 December 2020

Expression of Integrin beta3 is correlated to the properties of quiescent hemopoietic stem cells possessing the side population phenotype

1 reference

12 December 2020

Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches

1 reference

12 December 2020

Overexpression of CXCR4 predicts adverse overall and event-free survival in patients with unmutated FLT3 acute myeloid leukemia with normal karyotype

1 reference

12 December 2020

Effects of AMD3100 on transmigration and survival of acute myelogenous leukemia cells

1 reference

12 December 2020

VEGFR-1 (FLT-1), beta1 integrin, and hERG K+ channel for a macromolecular signaling complex in acute myeloid leukemia: role in cell migration and clinical outcome

1 reference

12 December 2020

Protective role of connexin 32 in steady-state hematopoiesis, regeneration state, and leukemogenesis.

1 reference

12 December 2020

The Role of Platelet/Endothelial Cell Adhesion Molecule 1 (CD31) and CD38 Antigens in Marrow Microenvironmental Retention of Acute Myelogenous Leukemia Cells

1 reference

12 December 2020

Combination therapy of an anticancer drug with the FNIII14 peptide of fibronectin effectively overcomes cell adhesion-mediated drug resistance of acute myelogenous leukemia

1 reference

12 December 2020

Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development

1 reference

12 December 2020

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

1 reference

12 December 2020

The CXCR4 antagonist AMD3100 impairs survival of human AML cells and induces their differentiation

1 reference

12 December 2020

Very late antigen-4 function of myeloblasts correlates with improved overall survival for patients with acute myeloid leukemia

1 reference

12 December 2020

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML.

1 reference

12 December 2020

CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure

1 reference

12 December 2020

Prognostic value of CXCR4 and FAK expression in acute myelogenous leukemia.

1 reference

12 December 2020

Cadherin-bound beta-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between beta-catenin pools

1 reference

12 December 2020

Environment-mediated drug resistance: a major contributor to minimal residual disease

1 reference

12 December 2020

1 reference

12 December 2020

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

1 reference

12 December 2020

Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice.

1 reference

12 December 2020

Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.

1 reference

12 December 2020

High expression of the very late antigen-4 integrin independently predicts reduced risk of relapse and improved outcome in pediatric acute myeloid leukemia: a report from the children's oncology group

1 reference

12 December 2020

Low-expression of E-cadherin in leukaemia cells causes loss of homophilic adhesion and promotes cell growth

1 reference

12 December 2020

Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cells

1 reference

12 December 2020

The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization.

1 reference

12 December 2020

Identification and characterization of a novel integrin-linked kinase inhibitor

1 reference

12 December 2020

AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias

1 reference

12 December 2020

A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia

1 reference

12 December 2020

Dependence of acute myeloid leukemia on adhesion within the bone marrow microenvironment.

1 reference

12 December 2020

Risk of natalizumab-associated progressive multifocal leukoencephalopathy

1 reference

12 December 2020

Discordant immunophenotypic profiles of adhesion molecules and cytokines in acute myeloid leukemia involving bone marrow and skin

1 reference

12 December 2020

The origins of the molecular era of adhesion research

1 reference

12 December 2020

BMS-936564/MDX-1338: a fully human anti-CXCR4 antibody induces apoptosis in vitro and shows antitumor activity in vivo in hematologic malignancies

1 reference

12 December 2020

DNA released by leukemic cells contributes to the disruption of the bone marrow microenvironment

1 reference

12 December 2020

Role of CXCR4 in the pathogenesis of acute myeloid leukemia

1 reference

12 December 2020

β2 integrin-derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis

1 reference

12 December 2020

High syndecan-1 levels in acute myeloid leukemia are associated with bleeding, thrombocytopathy, endothelial cell damage, and leukocytosis

1 reference

12 December 2020

Hematopoietic stem and progenitor cell mobilization in mice and humans by a first-in-class mirror-image oligonucleotide inhibitor of CXCL12.

1 reference

12 December 2020

Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy

1 reference

12 December 2020

Dynamic chemotherapy-induced upregulation of CXCR4 expression: a mechanism of therapeutic resistance in pediatric AML.

1 reference

12 December 2020

In Vivo RNAi screening identifies a leukemia-specific dependence on integrin beta 3 signaling

1 reference

12 December 2020

CXCR4-SERINE339 regulates cellular adhesion, retention and mobilization, and is a marker for poor prognosis in acute myeloid leukemia.

1 reference

12 December 2020

Regulatory systems in bone marrow for hematopoietic stem/progenitor cells mobilization and homing.

1 reference

12 December 2020

Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche.

1 reference

12 December 2020

Activity of the hypoxia-activated prodrug, TH-302, in preclinical human acute myeloid leukemia models.

1 reference

12 December 2020

The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization

1 reference

12 December 2020

Leukaemogenesis induced by an activating β-catenin mutation in osteoblasts

1 reference

12 December 2020

Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance

1 reference

12 December 2020

Functional integration of acute myeloid leukemia into the vascular niche.

1 reference

12 December 2020

Posttranscriptional control of the chemokine receptor CXCR4 expression in cancer cells.

1 reference

12 December 2020

Redox modulation of adjacent thiols in VLA-4 by AS101 converts myeloid leukemia cells from a drug-resistant to drug-sensitive state

1 reference

12 December 2020

Expression of Eph A4, Eph B2 and Eph B4 receptors in AML.

1 reference

12 December 2020

The role of adhesion molecules in acute myeloid leukemia and (hemato)oncology: a systematic review.

1 reference

12 December 2020

Making sense of hematopoietic stem cell niches

1 reference

12 December 2020

Acute myeloid leukemia in the vascular niche.

1 reference

12 December 2020

Concise Review: CXCR4/CXCL12 Signaling in Immature Hematopoiesis--Lessons From Pharmacological and Genetic Models

1 reference

12 December 2020

Biology and Clinical Relevance of Acute Myeloid Leukemia Stem Cells.

1 reference

12 December 2020

VLA-4 and CXCR4 expression levels show contrasting prognostic impact (favorable and unfavorable, respectively) in acute myeloid leukemia

1 reference

12 December 2020

Prognostic value of the expression of phosphatase and tensin homolog and CD44 in elderly patients with refractory acute myeloid leukemia

1 reference

12 December 2020

Paradigms lost-an emerging role for over-expression of tight junction adhesion proteins in cancer pathogenesis

1 reference

12 December 2020

Cx25 contributes to leukemia cell communication and chemosensitivity.

1 reference

12 December 2020

An update of current treatments for adult acute myeloid leukemia

1 reference

12 December 2020

Targeting the leukemia-stroma interaction in acute myeloid leukemia: rationale and latest evidence

1 reference

12 December 2020

Phase I study of evofosfamide, an investigational hypoxia-activated prodrug, in patients with advanced leukemia

1 reference

12 December 2020

Integrin alphavbeta3 enhances β-catenin signaling in acute myeloid leukemia harboring Fms-like tyrosine kinase-3 internal tandem duplication mutations: implications for microenvironment influence on sorafenib sensitivity

1 reference

12 December 2020

Concise Review: Stem Cells and Epithelial-Mesenchymal Transition in Cancer: Biological Implications and Therapeutic Targets.

1 reference

12 December 2020

AMD3100 and G-CSF disrupt the cross-talk between leukemia cells and the endosteal niche and enhance their sensitivity to chemotherapeutic drugs in biomimetic polystyrene scaffolds.

1 reference

12 December 2020

CDH1 (E-cadherin) expression independently affects clinical outcome in acute myeloid leukemia with normal cytogenetics.

1 reference

12 December 2020

MLL-AF9 Expression in Hematopoietic Stem Cells Drives a Highly Invasive AML Expressing EMT-Related Genes Linked to Poor Outcome.

1 reference

12 December 2020

Activation of the complement cascade enhances motility of leukemic cells by downregulating expression of HO-1

1 reference

12 December 2020

Concise Review: The Malignant Hematopoietic Stem Cell Niche

1 reference

12 December 2020

The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling.

1 reference

12 December 2020

AML1/ETO accelerates cell migration and impairs cell-to-cell adhesion and homing of hematopoietic stem/progenitor cells.

1 reference

12 December 2020

The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia.

1 reference

12 December 2020

CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia

1 reference

12 December 2020

The CCL2/CCR2 Axis Affects Transmigration and Proliferation but Not Resistance to Chemotherapy of Acute Myeloid Leukemia Cells

1 reference

12 December 2020

Biology and relevance of human acute myeloid leukemia stem cells

1 reference

12 December 2020

Targeting the CXCL12/CXCR4 axis in acute myeloid leukemia: from bench to bedside

1 reference

12 December 2020

Treatment of Relapsed/Refractory Acute Myeloid Leukemia

1 reference

12 December 2020

Bone Marrow Homing and Engraftment Defects of Human Hematopoietic Stem and Progenitor Cells

1 reference

12 December 2020

Current Developments in Mobilization of Hematopoietic Stem and Progenitor Cells and Their Interaction with Niches in Bone Marrow

1 reference

12 December 2020

Osteopontin b and c isoforms: Molecular Candidates Associated with Leukemic Stem Cell Chemoresistance in Acute Myeloid Leukemia

1 reference

12 December 2020

Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion.

1 reference

12 December 2020

Chimeric antigen receptor T-cell therapies for multiple myeloma

1 reference

12 December 2020

The Possible Importance of β3 Integrins for Leukemogenesis and Chemoresistance in Acute Myeloid Leukemia.

1 reference

12 December 2020

Roles of the bone marrow niche in hematopoiesis, leukemogenesis, and chemotherapy resistance in acute myeloid leukemia

1 reference

12 December 2020

Upregulation of the EMT marker vimentin is associated with poor clinical outcome in acute myeloid leukemia.

1 reference

12 December 2020

Understanding the molecular basis of acute myeloid leukemias: where are we now?

1 reference

12 December 2020

Initial Report of a Phase I Study of LY2510924, Idarubicin, and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia

1 reference

12 December 2020

Identifiers

DOI

10.3390/CELLS8010066

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658474%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30658474%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

PubMed publication ID

30658474

1 reference