(Q64991024)

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Integration of Genomic Data with NMR Analysis Enables Assignment of the Full Stereostructure of Neaumycin B, a Potent Inhibitor of Glioblastoma from a Marine-Derived Micromonospora.

scientific article published on 20 August 2018

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16 April 2020

Integration of Genomic Data with NMR Analysis Enables Assignment of the Full Stereostructure of Neaumycin B, a Potent Inhibitor of Glioblastoma from a Marine-Derived Micromonospora (English)

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16 April 2020

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William H. Fenical

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16 April 2020

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Min Cheol Kim

1

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16 April 2020

Henrique Machado

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16 April 2020

Kyoung Hwa Jang

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16 April 2020

Lynnie Trzoss

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16 April 2020

Paul R Jensen

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16 April 2020

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Journal of the American Chemical Society

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20 August 2018

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16 April 2020

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19 March 2024

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Journal of the American Chemical Society

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16 April 2020

140

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16 April 2020

34

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16 April 2020

10775-10784

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16 April 2020

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Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation

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https://pubmed.ncbi.nlm.nih.gov/30085661

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Modular organization of genes required for complex polyketide biosynthesis

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FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics

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Cytovaricin, a novel antibiotic

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Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

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Structure of the spiroketal-macrolide ossamycin

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Stereochemical Determination of Acyclic Structures Based on Carbon-Proton Spin-Coupling Constants. A Method of Configuration Analysis for Natural Products

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Computational approach for prediction of domain organization and substrate specificity of modular polyketide synthases

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Antifungal agents: mechanisms of action

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Axinelloside A, an unprecedented highly sulfated lipopolysaccharide inhibiting telomerase, from the marine sponge, Axinella infundibula.

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Tacrolimus (FK506) versus cyclosporine microemulsion (neoral) as maintenance immunosuppression therapy in kidney transplant recipients

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Molecular Basis of Celmer's Rules: Stereochemistry of Catalysis by Isolated Ketoreductase Domains from Modular Polyketide Synthases

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12 December 2020

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Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

1 reference

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Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30085661

12 December 2020

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Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica

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Phase II Trial of Ixabepilone, an Epothilone B Analog, in Patients With Metastatic Breast Cancer Previously Untreated With Taxanes

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Marine macrolides, a promising source of antitumor compounds.

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The biochemical basis for stereochemical control in polyketide biosynthesis

1 reference

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Structure and absolute configuration of karlotoxin-2, an ichthyotoxin from the marine dinoflagellate Karlodinium veneficum.

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The medicinal potential of promising marine macrolides with anticancer activity

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Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

1 reference

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Neaumycin: a new macrolide from Streptomyces sp. NEAU-x211.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30085661

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Relative configuration of JBIR-129, a cytotoxic 34-membered glycosidic polyol macrolide from Streptomyces sp. RK74

1 reference

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1 reference

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10.1021/JACS.8B04848

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30085661%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30085661%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30085661%20AND%20SRC:MED&resulttype=core&format=json

16 April 2020

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