(Q73235288)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Identification of a mutant amyloid peptide that predominantly forms neurotoxic protofibrillar aggregates (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference

Isam Qahwash

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Katherine L Weiland

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Yifeng Lu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Ronald W Sarver

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Rolf F Kletzien

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Riqiang Yan

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

English

0 references

publication date

8 April 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

2 November 2019

number of pages

9

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

page(s)

23187-23195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

2 November 2019

cites work

1 reference

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

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Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

21 January 2018

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Neurofibrillary tangles of Alzheimer disease share antigenic determinants with the axonal microtubule-associated protein tau (tau)

21 January 2018

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Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

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Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

21 January 2018

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

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Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

21 January 2018

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

21 January 2018

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Purification and cloning of amyloid precursor protein beta-secretase from human brain

21 January 2018

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gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

21 January 2018

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Amyloid diseases: abnormal protein aggregation in neurodegeneration

21 January 2018

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Structural and kinetic features of amyloid beta-protein fibrillogenesis.

21 January 2018

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An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

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Biochemical evidence for the long-tail form (A beta 1-42/43) of amyloid beta protein as a seed molecule in cerebral deposits of Alzheimer's disease.

21 January 2018

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In situ characterization of beta-amyloid in Alzheimer's diseased tissue by synchrotron Fourier transform infrared microspectroscopy

21 January 2018

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Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies.

21 January 2018

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Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

21 January 2018

1 reference

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Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

21 January 2018

1 reference

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Amyloid beta protein-induced neuronal cell death: neurotoxic properties of aggregated amyloid beta protein.

21 January 2018

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Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 January 2018

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

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Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates

21 January 2018

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Employing a superior BACE1 cleavage sequence to probe cellular APP processing

21 January 2018

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The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

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Information content in the circular dichroism of proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213298200

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

21 January 2018

1 reference

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New Class of Inhibitors of Amyloid-beta Fibril Formation. IMPLICATIONS FOR THE MECHANISM OF PATHOGENESIS IN ALZHEIMER'S DISEASE

21 January 2018

1 reference

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Arrest of beta-amyloid fibril formation by a pentapeptide ligand

21 January 2018

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Methionine 35 oxidation reduces fibril assembly of the amyloid abeta-(1-42) peptide of Alzheimer's disease

21 January 2018

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Human Bcl-2 protects against AMPA receptor-mediated apoptosis

21 January 2018

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Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis

21 January 2018

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Beta-amyloid-induced activation of caspase-3 in primary cultures of rat neurons

21 January 2018

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

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Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M213298200

Comparison of the aggregation properties, secondary structure and apoptotic effects of wild-type, Flemish and Dutch N-terminally truncated amyloid beta peptides

21 January 2018

1 reference

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Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy.

21 January 2018

1 reference

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Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

21 January 2018

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On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants

21 January 2018

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The alpha-helical to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation

21 January 2018

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Inhibition of Alzheimer's amyloidosis by peptides that prevent beta-sheet conformation

21 January 2018

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Inhibition of amyloid formation: a strategy to delay the onset of Alzheimer's disease.

21 January 2018

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Solution Structures of β Peptide and Its Constituent Fragments: Relation to Amyloid Deposition

21 January 2018

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The influence of the central region containing residues 19-25 on the aggregation properties and secondary structure of Alzheimer's beta-amyloid peptide.

21 January 2018

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In vitro studies of amyloid beta-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692-->Gly) Alzheimer's disease

21 January 2018

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The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation

21 January 2018

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Amino-terminal deletions enhance aggregation of beta-amyloid peptides in vitro

21 January 2018

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Toxicity of pyroglutaminated amyloid beta-peptides 3(pE)-40 and -42 is similar to that of A beta1-40 and -42.

21 January 2018

1 reference

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Growth of beta-amyloid(1-40) protofibrils by monomer elongation and lateral association. Characterization of distinct products by light scattering and atomic force microscopy.

21 January 2018

1 reference

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Mutant genes in familial Alzheimer's disease and transgenic models

21 January 2018

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Apoptosis in the nervous system

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M213298200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12684519%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference