(Q73282252)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Evidence for a role of Smad3 and Smad2 in stabilization of the tumor-derived mutant Smad2.Q407R (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

8

1 reference

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2 November 2019

author name string

Emmanuelle Dumont

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

François Lallemand

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Céline Prunier

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Nathalie Ferrand

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

André Guillouzo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Bruno Clément

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Azeddine Atfi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

language of work or name

English

0 references

publication date

16 April 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

2 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

volume

278

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

issue

27

1 reference

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2 November 2019

page(s)

24881-24887

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

TGF-beta signal transduction

2 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Smads as transcriptional co-modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Transforming growth factor beta signaling mediators and modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

A transcriptional partner for MAD proteins in TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Smad4 and FAST-1 in the assembly of activin-responsive factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Smad6 inhibits signalling by the TGF-beta superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Smads: transcriptional activators of TGF-beta responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Ski/Sno and TGF-beta signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

TGF-beta-mediated hepatocellular apoptosis by rat and human hepatoma cells and primary rat hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Gene mutation of transforming growth factor beta1 type II receptor in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Microsatellite instability in European hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Transforming growth factor-beta 1 (TGF-beta 1) and TGF-beta 1 receptors in normal, cirrhotic, and neoplastic human livers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Smad2 and Smad4 gene mutations in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

TGF-beta signaling and cancer: structural and functional consequences of mutations in Smads.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Induction of apoptosis by DPC4, a transcriptional factor regulated by transforming growth factor-beta through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Evidence that Smad2 is a tumor suppressor implicated in the control of cellular invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Crystal Structure of a Phosphorylated Smad2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor beta signaling by targeting Smads to the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Loss of Smad4 function in pancreatic tumors: C-terminal truncation leads to decreased stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Ubiquitin-dependent degradation of TGF-beta-activated smad2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Mechanism for mutational inactivation of the tumor suppressor Smad2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

A single missense mutant of Smad3 inhibits activation of both Smad2 and Smad3, and has a dominant negative effect on TGF-beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

Smad3 mutant mice develop metastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212496200

21 January 2018

Identifiers

DOI

10.1074/JBC.M212496200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12700238%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

1 reference