(Q73827681)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11332649%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Impact of age on hypermutation of immunoglobulin variable genes in humans (English)

1 reference

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7 November 2019

author name string

K Rosner

1

1 reference

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7 November 2019

D B Winter

2

1 reference

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7 November 2019

C Kasmer

3

1 reference

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7 November 2019

G L Skovgaard

4

1 reference

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7 November 2019

R E Tarone

5

1 reference

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7 November 2019

V A Bohr

6

1 reference

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7 November 2019

P J Gearhart

7

1 reference

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7 November 2019

publication date

1 March 2001

1 reference

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7 November 2019

number of pages

14

1 reference

Journal of Clinical Immunology

inferred from page(s)

published in

1 reference

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7 November 2019

volume

21

1 reference

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7 November 2019

page(s)

102-115

1 reference

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7 November 2019

issue

2

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https://scigraph.springernature.com/pub.10.1023/a:1011003821798

7 November 2019

exact match

0 references

cites work

Dual enigma of somatic hypermutation of immunoglobulin variable genes: targeting and mechanism.

1 reference

12 December 2020

High frequency of somatically mutated IgM molecules in the human adult blood B cell repertoire.

1 reference

12 December 2020

Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein

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12 December 2020

DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells

1 reference

12 December 2020

Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications

1 reference

12 December 2020

Molecular Biology of Aging

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12 December 2020

Bias in somatic hypermutation of human VH genes.

1 reference

12 December 2020

Mismatch repair deficiency interferes with the accumulation of mutations in chronically stimulated B cells and not with the hypermutation process

1 reference

12 December 2020

Structural repertoire of the human VH segments

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12 December 2020

Content and organization of the human Ig VH locus: definition of three new VH families and linkage to the Ig CH locus

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12 December 2020

Autoantibodies encoded by the most Jh-proximal human immunoglobulin heavy chain variable region gene

1 reference

12 December 2020

PMS2-deficiency diminishes hypermutation of a lambda1 transgene in young but not older mice

1 reference

12 December 2020

Transcriptional and posttranscriptional control of immunoglobulin mRNA production during B lymphocyte development

1 reference

12 December 2020

Codon bias targets mutation.

1 reference

12 December 2020

An anti-lipid A antibody obtained from the human fetal repertoire is encoded by VH6-V lambda 1 genes

1 reference

12 December 2020

poliota, a remarkably error-prone human DNA polymerase

1 reference

12 December 2020

On the origin of multiple mutations in human cancers

1 reference

12 December 2020

Quality control by DNA repair

1 reference

12 December 2020

Mismatch repair deficiency in phenotypically normal human cells

1 reference

12 December 2020

Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes

1 reference

12 December 2020

Ig VH hypermutation is absent in the germinal centers of aged mice

1 reference

12 December 2020

Mammalian DNA mismatch repair

1 reference

12 December 2020

The contribution of somatic hypermutation to the diversity of serum immunoglobulin: dramatic increase with age

1 reference

12 December 2020

Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting

1 reference

12 December 2020

Immunoglobulin VH gene expression in human aging

1 reference

12 December 2020

Low fidelity DNA synthesis by human DNA polymerase-eta.

1 reference

12 December 2020

Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2

1 reference

12 December 2020

1 reference

12 December 2020

Mismatch repair co-opted by hypermutation.

1 reference

12 December 2020

Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells

1 reference

12 December 2020

The effect of donor age on the processing of UV-damaged DNA by cultured human cells: reduced DNA repair capacity and increased DNA mutability

1 reference

12 December 2020

Immunoglobulin heavy chain junctional diversity in young and aged humans

1 reference

12 December 2020

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

12 December 2020

Spontaneous length variation in microsatellite DNA from human T-cell clones.

1 reference

12 December 2020

Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice

1 reference

12 December 2020

Cell-cycle-regulated DNA double-stranded breaks in somatic hypermutation of immunoglobulin genes

1 reference

12 December 2020

Expressed human immunoglobulin kappa genes and their hypermutation

1 reference

12 December 2020

Frequent occurrence of deletions and duplications during somatic hypermutation: implications for oncogene translocations and heavy chain disease

1 reference

12 December 2020

Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes

1 reference

12 December 2020

Mitochondrial DNA repair pathways

1 reference

12 December 2020

B cells are generated throughout life in humans

1 reference

12 December 2020

Molecular characterization of human antibodies to bacterial antigens: utilization of the less frequently expressed VH2 and VH6 heavy chain variable region gene families

1 reference

12 December 2020

The smaller human VH gene families display remarkably little polymorphism

1 reference

12 December 2020

Hypermutation, diversity and dissemination of human intestinal lamina propria plasma cells.

1 reference

12 December 2020

DNA Double-Strand Breaks in Immunoglobulin Genes Undergoing Somatic Hypermutation

1 reference

12 December 2020

Clusters of point mutations are found exclusively around rearranged antibody variable genes

1 reference

12 December 2020

Variable region gene analysis of B cell subsets derived from a 4-year-old child: somatically mutated memory B cells accumulate in the peripheral blood already at young age.

1 reference

12 December 2020

1 reference

12 December 2020

Evidence for a large compartment of IgM-expressing memory B cells in humans.

1 reference

12 December 2020

A human follicular lymphoma B cell line hypermutates its functional immunoglobulin genes in vitro

1 reference

12 December 2020

Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes

1 reference

12 December 2020

Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individuals

1 reference

12 December 2020

1 reference

12 December 2020

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice

1 reference

12 December 2020

Effect of age on humoral immunity, selection of the B-cell repertoire and B-cell development.

1 reference

12 December 2020

Predicting regional mutability in antibody V genes based solely on di- and trinucleotide sequence composition

1 reference

12 December 2020

Human IgM+IgD+ B cells, the major B cell subset in the peripheral blood, express V kappa genes with no or little somatic mutation throughout life.

1 reference

12 December 2020