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IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma
scientific article published on 01 July 2000
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scholarly article
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Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
title
IGF-I receptor activation and BCL-2 overexpression prevent early apoptotic events in human neuroblastoma
(English)
1 reference
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Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
main subject
neuroblastoma
1 reference
based on heuristic
inferred from title
apoptotic process
1 reference
based on heuristic
inferred from title
author
Eva Feldman
series ordinal
3
1 reference
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Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
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8 November 2019
author name string
van Golen CM
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
Castle VP
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
publication date
1 July 2000
1 reference
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Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
published in
Cell Death & Differentiation
1 reference
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Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
volume
7
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Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
issue
7
1 reference
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Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
page(s)
654-665
1 reference
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Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
cites work
Biology and treatment of neuroblastoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Biology and genetics of human neuroblastomas.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuroblastoma and insulin-like growth factor system. New insights and clinical perspectives.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
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Apoptosis in development and disease of the nervous system: II. Apoptosis in childhood neurologic disease.
1 reference
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Crossref
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7 January 2021
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Dissociation of mitogenesis and transforming activity by C-terminal truncation of the insulin-like growth factor-I receptor
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
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inferred from DOI database lookup
Effect of mutations at serines 1280-1283 on the mitogenic and transforming activities of the insulin-like growth factor I receptor
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
inferred from DOI database lookup
Different Effects on Mitogenesis and Transformation of a Mutation at Tyrosine 1251 of the Insulin-like Growth Factor I Receptor
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin receptor substrate 2 and Shc play different roles in insulin-like growth factor I signaling
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
inferred from DOI database lookup
Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of neuronal survival by the serine-threonine protein kinase Akt
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 and the regulation of programmed cell death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis. Breaking the ICE.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Channel formation by antiapoptotic protein Bcl-2.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-x(L) forms an ion channel in synthetic lipid membranes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Type I insulin-like growth factor receptor activation regulates apoptotic proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human ICE/CED-3 protease nomenclature
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases and caspase inhibitors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
inferred from DOI database lookup
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
inferred from DOI database lookup
CrmA-inhibitable cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein during Fas- and tumor necrosis factor-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
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7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like Growth Factor-II as a Paracrine Growth Factor in Human Neuroblastoma Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Double identity for proteins of the Bcl-2 family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mitochondrial death/life regulator in apoptosis and necrosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like growth factors and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like growth factor expression in human cancer cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like growth factor-I is an osmoprotectant in human neuroblastoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The insulin-like growth factor-I receptor signaling pathways are important for tumorigenesis and inhibition of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth regulation of human glioblastoma T98G cells by insulin-like growth factor-1 and its receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dominant negative inhibition of tumorigenesis in vivo by human insulin-like growth factor I receptor mutant
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of the human insulinlike growth factor I receptor promotes ligand-dependent neoplastic transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncogenes and the strategy of growth factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like growth factor-I promotes multidrug resistance in MCLM colon cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Role of CED-3-Related Cysteine Proteases in Apoptosis of Cerebellar Granule Cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serum deprivation-induced apoptosis in cultured hippocampi is prevented by kainate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct mode of apoptosis induced by genotoxic agent etoposide and serum withdrawal in neuroblastoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Soluble integrin ligands and growth factors independently rescue neuroblastoma cells from apoptosis under nonadherent conditions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin-like growth factor-I prevents apoptosis in neurons after nerve growth factor withdrawal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of CPP32-like protease activity following apoptotic challenge in SH-SY5Y neuroblastoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase activation accompanying cytochrome c release from mitochondria is possibly involved in nitric oxide-induced neuronal apoptosis in SH-SY5Y cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for activation of caspase-3-like protease in excitotoxin- and hypoxia/hypoglycemia-injured neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dysregulation of the type 1 IGF receptor as a paradigm in tumor progression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpressed IGF-I receptors reduce estrogen growth requirements, enhance survival, and promote E-cadherin-mediated cell-cell adhesion in human breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 gene family in the nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 expression in neural cells blocks activation of ICE/CED-3 family proteases during apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bax directly induces release of cytochrome c from isolated mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 regulates amplification of caspase activation by cytochrome c.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.CDD.4400693
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.CDD.4400693
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
PubMed publication ID
10889510
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10889510
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10889510%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 November 2019
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