(Q74496847)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9566442%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

In vitro analysis of the activity of the major human hepatic CYP enzyme (CYP3A4) using [N-methyl-14C]-erythromycin (English)

1 reference

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11 November 2019

author name string

R J Riley

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9566442%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

D Howbrook

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9566442%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

publication date

1 December 1997

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9566442%20AND%20SRC:MED&resulttype=core&format=json

Journal of Pharmacological and Toxicological Methods

11 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9566442%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

38

1 reference

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11 November 2019

issue

4

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11 November 2019

page(s)

189-193

1 reference

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Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

11 November 2019

cites work

1 reference

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7 January 2021

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

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7 January 2021

The role of cytochrome P4502D6 in the metabolism of paroxetine by human liver microsomes

1 reference

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7 January 2021

Determination of P4501A2 activity in human liver microsomes using [3-14C-methyl]caffeine

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7 January 2021

Effect of age and gender on the activity of human hepatic CYP3A

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7 January 2021

Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

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7 January 2021

The erythromycin breath test selectively measures P450IIIA in patients with severe liver disease

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7 January 2021

The erythromycin breath test predicts the clearance of midazolam.

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7 January 2021

Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA.

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7 January 2021

In vitro interaction between cyclosporin A and macrolide antibiotics

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7 January 2021

The colorimetric estimation of formaldehyde by means of the Hantzsch reaction

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7 January 2021

P450 in the rat and man: methods of investigation, substrate specificities and relevance to cancer

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7 January 2021

Expression and inducibility of antigens in severe combined immunodeficient mice recognized by human anti-P450 antibodies

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7 January 2021

Use of in vitro human metabolism studies in drug development. An industrial perspective

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7 January 2021

Measurement of liver microsomal cytochrome p450 (CYP2D6) activity using [O-methyl-14C]dextromethorphan

1 reference

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7 January 2021

Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients

1 reference

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7 January 2021

In vitro methods for assessing human hepatic drug metabolism: their use in drug development

1 reference

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7 January 2021

Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine.

1 reference

https://api.crossref.org/works/10.1016%2FS1056-8719%2897%2900103-2

7 January 2021

Effects of roxithromycin, erythromycin and troleandomycin on their N-demethylation by rat and human cytochrome P450 enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS1056-8719%2897%2900103-2

7 January 2021

Induction, purification, and characterization of cytochrome P450IIE.

1 reference

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7 January 2021

Human liver microsomal cytochrome P450 3A isozymes mediated vindesine biotransformation. Metabolic drug interactions

1 reference

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7 January 2021

10.1016/S1056-8719(97)00103-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9566442%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference