(Q74603366)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

title

A melanoma-predisposing germline CDKN2A mutation with functional significance for both p16 and p14ARF (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Klas Wiman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

author name string

Jamileh Hashemi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Charlotte Asker

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Anton Platz

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Johan Hansson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

language of work or name

English

0 references

publication date

1 June 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

volume

180

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

page(s)

211-221

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

12 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

1 reference

7 January 2021

p53-induced apoptosis as a safeguard against cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Functional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

1 reference

7 January 2021

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Contribution of two independent MDM2-binding domains in p14(ARF) to p53 stabilization

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

p16(MTS-1/CDKN2/INK4a) in cancer progression

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Molecular genetics of familial cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Hereditary cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

A melanoma-associated germline mutation in exon 1beta inactivates p14ARF.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Mutations in theINK4a/ARFMelanoma Susceptibility Locus Functionally Impair p14ARF

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Functional reassessment of P16 variants using a transfection-based assay

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0304-3835%2802%2900027-7

7 January 2021

10.1016/S0304-3835(02)00027-7

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12175554%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference