(Q77654045)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

title

Involvement of human cytochromes P450 (CYP) in the reductive metabolism of AQ4N, a hypoxia activated anthraquinone di-N-oxide prodrug (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

5

L H Patterson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

4

S R McKeown

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

author name string

S M Raleigh

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

E Wanogho

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

M D Burke

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

language of work or name

English

0 references

publication date

1 November 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Radiation Oncology Biology Physics

7 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

volume

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

page(s)

763-767

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

Tumour hypoxia: the picture has changed in the 1990s

7 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

The experimental development of bioreductive drugs and their role in cancer therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

DNA topoisomerase II-dependent cytotoxicity of alkylaminoanthraquinones and their N-oxides

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

AQ4N: an alkylaminoanthraquinone N-oxide showing bioreductive potential and positive interaction with radiation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Rationale for the use of aliphatic N-oxides of cytotoxic anthraquinones as prodrug DNA binding agents: a new class of bioreductive agent

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Tolbutamide hydroxylation by human liver microsomes. Kinetic characterisation and relationship to other cytochrome P-450 dependent xenobiotic oxidations

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Identification of the cytochrome P450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Bioactivation of the narcotic drug codeine in human liver is mediated by the polymorphic monooxygenase catalyzing debrisoquine 4-hydroxylation (cytochrome P-450 dbl/bufI)

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Xenobiotic metabolising enzyme expression in colonic neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Drug-metabolizing enzyme expression in human normal, peritumoral and tumoral colorectal tissue samples.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Cytochrome P450 expression is a common molecular event in soft tissue sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Expression of xenobiotic metabolizing enzymes in breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Immunohistochemical localization of cytochrome P450 3A in human pulmonary carcinomas and normal bronchial tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

Cytochrome P450 expression in oesophageal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

The immunohistochemical localization of drug-metabolizing enzymes in prostate cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0360-3016%2898%2900308-3

7 January 2021

10.1016/S0360-3016(98)00308-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9845092%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference