(Q78120133)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10445400%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

title

Homology modelling of human cytochromes P450 involved in xenobiotic metabolism and rationalization of substrate selectivity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10445400%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

author name string

D F Lewis

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10445400%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

publication date

1 July 1999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10445400%20AND%20SRC:MED&resulttype=core&format=json

Experimental and Toxicologic Pathology

11 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10445400%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

volume

51

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10445400%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

issue

4-5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10445400%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

page(s)

369-374

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10445400%20AND%20SRC:MED&resulttype=core&format=json

Cytochrome P450 proteins and potential utilization in biodegradation

11 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Xenobiotic-metabolizing cytochrome P450 enzymes in the human feto-placental unit: role in intrauterine toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Cloning and expression of cytochrome P450 genes controlling flower colour

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Identification of residues 99, 220, and 221 of human cytochrome P450 2C19 as key determinants of omeprazole activity

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Competitive inhibition of coumarin 7-hydroxylation by pilocarpine and its interaction with mouse CYP 2A5 and human CYP 2A6

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Three-dimensional models of human and other mammalian microsomal P450s constructed from an alignment with P450102 (P450bm3)

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

The CYP2 family: models, mutants and interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Molecular modelling of CYP1A subfamily members based on an alignment with CYP102: rationalization of CYP1A substrate specificity in terms of active site amino acid residues

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Molecular modelling and quantitative structure-activity relationship studies on the interaction of omeprazole with cytochrome P450 isozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

The P450 catalytic cycle and oxygenation mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and rationalization of CYP2E substrate specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Molecular modelling of human CYP2C subfamily enzymes CYP2C9 and CYP2C19: rationalization of substrate specificity and site-directed mutagenesis experiments in the CYP2C subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Molecular modelling of CYP3A4 from an alignment with CYP102: identification of key interactions between putative active site residues and CYP3A-specific chemicals

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Evolution of the cytochrome P450 superfamily: sequence alignments and pharmacogenetics

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

The metabolism of tamoxifen by human cytochromes P450 is rationalized by molecular modelling of the enzyme-substrate interactions: potential importance to its proposed anti-carcinogenic/carcinogenic actions

1 reference

https://api.crossref.org/works/10.1016%2FS0940-2993%2899%2980024-4

7 January 2021

10.1016/S0940-2993(99)80024-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10445400%20AND%20SRC:MED&resulttype=core&format=json

11 December 2019

1 reference