(Q78492717)

English

Interleukin-6 promotes the production of interleukin-4 and interleukin-5 by interleukin-2-dependent and -independent mechanisms in freshly isolated human T cells

scientific article published on 01 November 2002

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scholarly article

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Europe PubMed Central

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14 December 2019

Interleukin-6 promotes the production of interleukin-4 and interleukin-5 by interleukin-2-dependent and -independent mechanisms in freshly isolated human T cells (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12423307%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

4

object named as

Dirkje S Postma

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14 December 2019

author name string

Irene H Heijink

1

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14 December 2019

Edo Vellenga

2

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14 December 2019

Peter Borger

3

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14 December 2019

Jan G R de Monchy

5

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14 December 2019

Henk F Kauffman

6

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14 December 2019

publication date

1 November 2002

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14 December 2019

1 reference

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14 December 2019

107

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14 December 2019

3

1 reference

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14 December 2019

316-324

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14 December 2019

Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01501.X

21 January 2018

T cells are the principal source of interleukin-5 mRNA in allergen-induced rhinitis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01501.X

21 January 2018

Role of IL-6 in directing the initial immune response to schistosome eggs

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01501.X

21 January 2018

Signaling through CD5 activates a pathway involving phosphatidylinositol 3-kinase, Vav, and Rac1 in human mature T lymphocytes

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01501.X

21 January 2018

Reprogramming the signalling requirement for AP-1 (activator protein-1) activation during differentiation of precursor CD4+ T-cells into effector Th1 and Th2 cells.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01501.X

21 January 2018

Cooperative interaction of GATA-2 and AP1 regulates transcription of the endothelin-1 gene

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2567.2002.01501.X

21 January 2018

Modulatory effects of alveolar macrophages on CD4+ T-cell IL-5 responses correlate with IL-1beta, IL-6, and IL-12 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reprogramming transcription during the differentiation of precursor CD4+ T cells into effector Th1 and Th2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation of IL-5 gene by nontransformed human T cells through the proximal promoter element

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD28 co-stimulation restores T cell responsiveness in NOD mice by overcoming deficiencies in Rac-1/p38 mitogen-activated protein kinase signaling and IL-2 and IL-4 gene transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance of activated human Th2 cells to NO-induced apoptosis is mediated by gamma-glutamyltranspeptidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential activation of Rac-1, SEK-1/MKK-4, and protein kinase Cdelta is required for interleukin-6-induced STAT3 Ser-727 phosphorylation and transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominant TH2-like bronchoalveolar T-lymphocyte population in atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T lymphocytes and mast cells express messenger RNA for interleukin-4 in the nasal mucosa in allergen-induced rhinitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two pathways can activate the interleukin-5 gene and induce binding to the conserved lymphokine element 0.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased production of IFN gamma and increased production of IL-6 by cord blood mononuclear cells of newborns with a high risk of allergy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical role of IL-2 for the production and gene transcription of IL-5 in allergen-specific human T cell clones

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-5 production by bronchoalveolar lavage and peripheral blood mononuclear cells in asthma and atopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-7 upregulates the interleukin-2-gene expression in activated human T lymphocytes at the transcriptional level by enhancing the DNA binding activities of both nuclear factor of activated T cells and activator protein-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Ca2+/calmodulin-dependent kinase type IV is involved in the CD5-mediated signaling pathway in human T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-4, interferon-gamma and interleukin-5 in peripheral blood of children with moderate atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Augmentation of naive, Th1 and Th2 effector CD4 responses by IL-6, IL-1 and TNF

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Helper T cell differentiation is controlled by the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential responsiveness of the IL-5 and IL-4 genes to transcription factor GATA-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gene expression of the GATA-3 transcription factor is increased in atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the human interleukin-5 promoter by Ets transcription factors. Ets1 and Ets2, but not Elf-1, cooperate with GATA3 and HTLV-I Tax1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The absence of IL-6 does not affect Th2 cell development in vivo, but does lead to impaired proliferation, IL-2 receptor expression, and B cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional control of the IL-5 gene by human helper T cells: IL-5 synthesis is regulated independently from IL-2 or IL-4 synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral blood T lymphocytes from asthmatic patients are primed for enhanced expression of interleukin (IL)-4 and IL-5 mRNA: associations with lung function and serum IgE

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allergen challenge primes for IL-5 mRNA production and abrogates beta-adrenergic function in peripheral blood T lymphocytes from asthmatics

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 and leukemia inhibitory factor induction of JunB is regulated by distinct cell type-specific cis-acting elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/12423307

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2567.2002.01501.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12423307%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12423307%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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