(Q80568026)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

7

Rachael L Neve

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Daphna Laifenfeld

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Lucas J Patzek

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Donna L McPhie

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Yuzhi Chen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Yona Levites

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Anne M Cataldo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

publication date

1 July 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

issue

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

page(s)

7141-7153

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

1 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6794581/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Endocytosis and cancer.

1 reference

12 December 2020

Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

1 reference

12 December 2020

Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death.

1 reference

12 December 2020

ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics

1 reference

12 December 2020

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

1 reference

12 December 2020

EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake.

1 reference

12 December 2020

Interactions of rotavirus VP4 spike protein with the endosomal protein Rab5 and the prenylated Rab acceptor PRA1.

1 reference

12 December 2020

beta-Secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations

1 reference

12 December 2020

Evidence for decreased transport of tryptophan hydroxylase in Alzheimer's disease

1 reference

12 December 2020

Nerve growth factor signaling, neuroprotection, and neural repair

1 reference

12 December 2020

Continual expression of Rab5(Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity

1 reference

12 December 2020

APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment

1 reference

12 December 2020

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

12 December 2020

The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes

1 reference

12 December 2020

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis

1 reference

12 December 2020

NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals

1 reference

12 December 2020

Annexin I targets S100C to early endosomes

1 reference

12 December 2020

Rab5 is a signalling GTPase involved in actin remodelling by receptor tyrosine kinases

1 reference

12 December 2020

Deficits in synaptic transmission and learning in amyloid precursor protein (APP) transgenic mice require C-terminal cleavage of APP.

1 reference

12 December 2020

Presenilin-dependent gamma-secretase on plasma membrane and endosomes is functionally distinct.

1 reference

12 December 2020

APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein

1 reference

12 December 2020

Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice

1 reference

12 December 2020

Overexpression in neurons of human presenilin-1 or a presenilin-1 familial Alzheimer disease mutant does not enhance apoptosis.

1 reference

12 December 2020

APP processing is regulated by cytoplasmic phosphorylation

1 reference

12 December 2020

The amyloid precursor protein interacts with Go heterotrimeric protein within a cell compartment specialized in signal transduction

1 reference

12 December 2020

Receptor downregulation and multivesicular-body sorting

1 reference

12 December 2020

A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

1 reference

12 December 2020

APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy

1 reference

12 December 2020

Cell biology: mitosis and membranes

1 reference

12 December 2020

Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production

1 reference

12 December 2020

Endocytosis and signaling cascades: a close encounter

1 reference

12 December 2020

Analysis of transferrin recycling in mitotic and interphase HeLa cells by quantitative fluorescence microscopy.

1 reference

12 December 2020

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5

1 reference

12 December 2020

Role of rab5 in EGF receptor-mediated signal transduction

1 reference

12 December 2020

The amyloid precursor protein-binding protein APP-BP1 drives the cell cycle through the S-M checkpoint and causes apoptosis in neurons

1 reference

12 December 2020

Reversal of Alzheimer's-like pathology and behavior in human APP transgenic mice by mutation of Asp664.

1 reference

12 December 2020

In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease.

1 reference

12 December 2020

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

1 reference

12 December 2020

The role of apoptotic pathways in Alzheimer's disease neurodegeneration and cell death

1 reference

12 December 2020

APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

1 reference

12 December 2020

Hrs, a tyrosine kinase substrate with a conserved double zinc finger domain, is localized to the cytoplasmic surface of early endosomes

1 reference

12 December 2020

Early endosomal localization of hrs requires a sequence within the proline- and glutamine-rich region but not the FYVE finger

1 reference

12 December 2020

Inhibition of clathrin-coated pit assembly by an Eps15 mutant.

1 reference

12 December 2020

APP-BP1 mediates APP-induced apoptosis and DNA synthesis and is increased in Alzheimer's disease brain

1 reference

12 December 2020

The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice

1 reference

12 December 2020

Expression of beta-amyloid precursor protein-CD3gamma chimeras to demonstrate the selective generation of amyloid beta(1-40) and amyloid beta(1-42) peptides within secretory and endocytic compartments

1 reference

12 December 2020

Abortive apoptosis in Alzheimer's disease.

1 reference

12 December 2020

Neuronal expression of beta-amyloid precursor protein Alzheimer mutations causes intracellular accumulation of a C-terminal fragment containing both the amyloid beta and cytoplasmic domains.

1 reference

12 December 2020

Ras-activated endocytosis is mediated by the Rab5 guanine nucleotide exchange activity of RIN1.

1 reference

12 December 2020

Presenilin 1 regulates pharmacologically distinct gamma -secretase activities. Implications for the role of presenilin in gamma -secretase cleavage

1 reference

12 December 2020

Alzheimer amyloid protein precursor complexes with brain GTP-binding protein G(o)

1 reference

12 December 2020

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

1 reference

12 December 2020

DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3

1 reference

12 December 2020

Aberrant expressions of pathogenic phenotype in Alzheimer's diseased transgenic mice carrying NSE-controlled APPsw.

1 reference

12 December 2020

Dynamin and endocytosis

1 reference

12 December 2020

Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases

1 reference

12 December 2020

A short cytoplasmic domain of the amyloid precursor protein induces apoptosis in vitro and in vivo.

1 reference

12 December 2020

Recycling of transferrin receptors in A431 cells is inhibited during mitosis

1 reference

12 December 2020

Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein

1 reference

12 December 2020

Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders.

1 reference

12 December 2020

Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including Abeta42

1 reference

12 December 2020

10.1523/JNEUROSCI.4599-06.2007

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17611268%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

17611268

1 reference