(Q80800472)

English

Interaction between the UCP2-866G/A, mtDNA 10398G/A and PGC1alpha p.Thr394Thr and p.Gly482Ser polymorphisms in type 2 diabetes susceptibility in North Indian population

scientific article published on 14 August 2007

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17701054%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

Interaction between the UCP2-866G/A, mtDNA 10398G/A and PGC1alpha p.Thr394Thr and p.Gly482Ser polymorphisms in type 2 diabetes susceptibility in North Indian population (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17701054%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

type 2 diabetes

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17701054%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

E Rai

1

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Europe PubMed Central

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3 January 2020

A Koul

3

1 reference

Europe PubMed Central

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3 January 2020

A K Bhat

4

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3 January 2020

A J S Bhanwer

5

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3 January 2020

R N K Bamezai

6

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3 January 2020

publication date

14 August 2007

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17701054%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17701054%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

122

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3 January 2020

5

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3 January 2020

535-540

1 reference

Europe PubMed Central

PubMed publication ID

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3 January 2020

https://scigraph.springernature.com/pub.10.1007/s00439-007-0421-4

0 references

Superoxide activates mitochondrial uncoupling proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of peroxisome proliferator-activated receptor-gamma coactivator-1alpha in the transcriptional regulation of the human uncoupling protein 2 gene in INS-1E cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial uncoupling-protein homologues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA G10398A polymorphism imparts maternal Haplogroup N a risk for breast and esophageal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling protein 2 promoter polymorphism -866G/A affects its expression in beta-cells and modulates clinical profiles of Japanese type 2 diabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA polymorphism: its role in longevity of the Irish population

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Report of the expert committee on the diagnosis and classification of diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contributions of insulin-resistance and insulin-secretory defects to the pathogenesis of type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive oxygen species have a causal role in multiple forms of insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A functional polymorphism in the promoter of UCP2 enhances obesity risk but reduces type 2 diabetes risk in obese middle-aged humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classification of European mtDNAs from an analysis of three European populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uncoupling protein 2 and islet function

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type 2 diabetes-a matter of beta-cell life and death?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC-1alpha Thr394Thr and Gly482Ser variants are significantly associated with T2DM in two North Indian populations: a replicate case-control study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type 2 diabetes: principles of pathogenesis and therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The possible role of 10398A and 16189C mtDNA variants in providing susceptibility to T2DM in two North Indian populations: a replicative study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial dysfunction and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17701054

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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