(Q81042311)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557797%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

BRCA1 and BRCA2 in breast cancer predisposition and recombination control (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557797%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

author name string

Ralph Scully

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557797%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

Anyong Xie

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557797%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

publication date

1 July 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557797%20AND%20SRC:MED&resulttype=core&format=json

Journal of Mammary Gland Biology and Neoplasia

5 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557797%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557797%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557797%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

page(s)

237-246

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15557797%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1023/b:jomg.0000048771.93906.3e

5 January 2020

exact match

0 references

cites work

Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development

1 reference

12 December 2020

Nine novel conserved motifs in BRCA1 identified by the chicken orthologue.

1 reference

12 December 2020

H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis

1 reference

12 December 2020

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

1 reference

12 December 2020

The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage and tumor suppression

1 reference

12 December 2020

Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint

1 reference

12 December 2020

Mutation and cancer: statistical study of retinoblastoma

1 reference

12 December 2020

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

1 reference

12 December 2020

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

1 reference

12 December 2020

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

1 reference

12 December 2020

Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains.

1 reference

12 December 2020

ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones.

1 reference

12 December 2020

Cancer susceptibility and the functions of BRCA1 and BRCA2

1 reference

12 December 2020

The importance of repairing stalled replication forks

1 reference

12 December 2020

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

1 reference

12 December 2020

Genetic analysis of BRCA1 function in a defined tumor cell line

1 reference

12 December 2020

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

1 reference

12 December 2020

MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways

1 reference

12 December 2020

NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain

1 reference

12 December 2020

The Schizosaccharomyces pombe rad3 checkpoint gene

1 reference

12 December 2020

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

1 reference

12 December 2020

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

1 reference

12 December 2020

RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

1 reference

12 December 2020

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

1 reference

12 December 2020

Megabase chromatin domains involved in DNA double-strand breaks in vivo

1 reference

12 December 2020

Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions

1 reference

12 December 2020

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

1 reference

12 December 2020

Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining

1 reference

12 December 2020

BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis.

1 reference

12 December 2020

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

1 reference

12 December 2020

BRCA1 at a branch point

1 reference

12 December 2020

Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors

1 reference

12 December 2020

Fork reversal and ssDNA accumulation at stalled replication forks owing to checkpoint defects

1 reference

12 December 2020

ATR Regulates Fragile Site Stability

1 reference

12 December 2020

MDC1 is required for the intra-S-phase DNA damage checkpoint

1 reference

12 December 2020

Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair

1 reference

12 December 2020

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

1 reference

12 December 2020

Brca1 controls homology-directed DNA repair

1 reference

12 December 2020

Direct DNA binding by Brca1

1 reference

12 December 2020

BRCA2 associates with acetyltransferase activity when bound to P/CAF

1 reference

12 December 2020

BRCA1: the enigma of tissue-specific tumor development.

1 reference

12 December 2020

A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication

1 reference

12 December 2020

The Fanconi road to cancer

1 reference

12 December 2020

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair

1 reference

12 December 2020

Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae

1 reference

12 December 2020

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

1 reference

12 December 2020

Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation.

1 reference

12 December 2020

Links between replication, recombination and genome instability in eukaryotes

1 reference

12 December 2020

The BRCA1 suppressor hypothesis: An explanation for the tissue-specific tumor development in BRCA1 patients

1 reference

12 December 2020

Follow-up study of twenty-four families with Li-Fraumeni syndrome

1 reference

12 December 2020

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

1 reference

12 December 2020

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

1 reference

12 December 2020

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair

1 reference

12 December 2020

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

1 reference

12 December 2020

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

1 reference

12 December 2020

Involvement of Brca2 in DNA repair

1 reference

12 December 2020

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

12 December 2020

Phenotypic effects of heterozygosity for a BRCA2 mutation

1 reference

12 December 2020

In search of the tumour-suppressor functions of BRCA1 and BRCA2

1 reference

12 December 2020

A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage.

1 reference

12 December 2020

Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability

1 reference

12 December 2020

Targeted disruption of the Rad51 gene leads to lethality in embryonic mice

1 reference

12 December 2020

BRCA2-dependent and independent formation of RAD51 nuclear foci.

1 reference

12 December 2020

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

12 December 2020

DNA double strand break repair and chromosomal translocation: lessons from animal models

1 reference

12 December 2020

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

1 reference

12 December 2020

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

1 reference

12 December 2020

Identification of the breast cancer susceptibility gene BRCA2

1 reference

12 December 2020

Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage

1 reference

12 December 2020

Biallelic inactivation of BRCA2 in Fanconi anemia

1 reference

12 December 2020

The DNA replication checkpoint response stabilizes stalled replication forks

1 reference

12 December 2020

BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans

1 reference

12 December 2020

Histone H2A variants H2AX and H2AZ

1 reference

12 December 2020

Breast and ovarian cancer

1 reference

12 December 2020

Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

1 reference

12 December 2020

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

1 reference

12 December 2020

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

1 reference

12 December 2020

Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b

1 reference

12 December 2020

The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair

1 reference

12 December 2020

BRCA1 supports XIST RNA concentration on the inactive X chromosome

1 reference

12 December 2020

Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50

1 reference

12 December 2020

Role of BRCA gene dysfunction in breast and ovarian cancer predisposition

1 reference

12 December 2020

Rescue of arrested replication forks by homologous recombination

1 reference

12 December 2020

Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation

1 reference

12 December 2020

Structure of a BRCA1-BARD1 heterodimeric RING-RING complex

1 reference

12 December 2020

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

1 reference

12 December 2020

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

1 reference

12 December 2020

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

1 reference

12 December 2020

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

1 reference

12 December 2020

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

1 reference

12 December 2020

Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2

1 reference

12 December 2020

Mass spectrometric and mutational analyses reveal Lys-6-linked polyubiquitin chains catalyzed by BRCA1-BARD1 ubiquitin ligase

1 reference

12 December 2020

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

1 reference

12 December 2020

Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci

1 reference

12 December 2020

Genomic instability in mice lacking histone H2AX

1 reference

12 December 2020

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

1 reference

12 December 2020

Absence of Brca2 causes genome instability by chromosome breakage and loss associated with centrosome amplification

1 reference

12 December 2020

BRCA1: exploring the links to transcription

1 reference

12 December 2020

Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1

1 reference

12 December 2020

BRCA1 RING domain cancer-predisposing mutations. Structural consequences and effects on protein-protein interactions

1 reference

12 December 2020

Association of BRCA1 with Rad51 in mitotic and meiotic cells

1 reference

12 December 2020

The BRCA2-Interacting Protein DSS1 Is Vital for DNA Repair, Recombination, and Genome Stability in Ustilago maydis

1 reference

12 December 2020

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

12 December 2020

BRCA1-independent ubiquitination of FANCD2

1 reference

12 December 2020

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

1 reference

12 December 2020

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

1 reference

12 December 2020

The Fanconi anaemia/BRCA pathway

1 reference

12 December 2020

Molecular views of recombination proteins and their control

1 reference

12 December 2020

The BRCT Domain Is a Phospho-Protein Binding Domain

1 reference

12 December 2020

DNA polymerase stalling, sister chromatid recombination and the BRCA genes

1 reference

12 December 2020

Brca2 is required for embryonic cellular proliferation in the mouse

1 reference

12 December 2020

MDC1 is a mediator of the mammalian DNA damage checkpoint

1 reference

12 December 2020

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

1 reference

12 December 2020

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

1 reference

12 December 2020

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

12 December 2020

Stabilization of stalled DNA replication forks by the BRCA2 breast cancer susceptibility protein

1 reference

12 December 2020

Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals

1 reference

12 December 2020

Initiation of genetic recombination and recombination-dependent replication

1 reference

12 December 2020

Transcriptional activation functions in BRCA2

1 reference

12 December 2020

The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin

1 reference

12 December 2020

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

1 reference

12 December 2020